Paper · 1994 · Biological and Pharmaceutical Bulletin

Phytogrowth-Inhibitory Activities of 2-Thiophenecarboxylic Acid and Its Related Compounds.

Yoshihiko INAMORI; Chikaaki MURO; Yuichiro FUNAKOSHI; et al.

9
claims
11
verbatim quotes
1
citations
2
research areas
✓
Open access

Abstract

2-Thiophenecarboxylic acid (I) exhibited growth-inhibitory activity in five kinds of plants. In particular, I strongly inhibited the growth of the roots of Lactuca sativa L. var. longifolia LAM and Echinochloa utilis OHWI et YABUNO, even at the low concentration of 5.0 x 10(-3) M. Furthermore, all of the I-related compounds (II-V and VII-X) except for VI, showed more or less obvious inhibitory activity on the seeds of Sesamum indicum L. Compounds VII-X, in which the carboxyl group of I was replaced by acetic acid, propionic acid, butyric acid and acrylic acid, and exhibited more potent phytogrowth-inhibitory activity than I. Among these compounds, 2-thiophenebutyric acid (IX) showed the strongest activity. Esterification of the carboxyl group in I increased the inhibitory activity relative to that of I, while amidation and reduction of this group markedly decreased its inhibitory activity. The radicles of the plants treated with each of the compounds except for VI showed negative geotropism, even though germination occurred.

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Claims 9

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

2-Thiophenecarboxylic acid inhibited growth in five plant kinds.

Taxon
plantsViridiplantaee0
Treatment
2-Thiophenecarboxylic acide0
Outcome
growth-inhibitory activitye0
Direction
growth-inhibitorye0
Value
five kindse0

Not reportedComparator

Verbatim

e0

“2-Thiophenecarboxylic acid (I) exhibited growth-inhibitory activity in five kinds of plants.”

✓ located verbatim in the source · abstract, characters 0–92 · show in text ↑
Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

At 5.0 x 10(-3) M, the compound strongly inhibited Lactuca root growth.

Taxon
Lactuca sativa L. var. longifolia LAMLactuca sativa var. longifoliae0
Organ / stage
rootse0
Treatment
Ie0
Outcome
growth of the rootse0
Direction
inhibitede0
Qualifier
5.0 x 10(-3) Me0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Lactuca sativa var. longifolia
Lactuca sativa var. longifolia · TaxonPublic domain · Wikimedia Commons ↗

Verbatim

e0

“I strongly inhibited the growth of the roots of Lactuca sativa L. var. longifolia LAM and Echinochloa utilis OHWI et YABUNO, even at the low concentration of 5.0 x 10(-3) M.”

✓ located verbatim in the source · abstract, characters 108–281 · show in text ↑
Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

At 5.0 x 10(-3) M, the compound strongly inhibited Echinochloa root growth.

Taxon
Echinochloa utilis OHWI et YABUNOEchinochloa esculentae0
Organ / stage
rootse0
Treatment
Ie0
Outcome
growth of the rootse0
Direction
inhibitede0
Qualifier
5.0 x 10(-3) Me0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Echinochloa esculenta
Echinochloa esculenta · Taxon · picture from its Wikimedia Commons categoryStefan.lefnaer · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“I strongly inhibited the growth of the roots of Lactuca sativa L. var. longifolia LAM and Echinochloa utilis OHWI et YABUNO, even at the low concentration of 5.0 x 10(-3) M.”

✓ located verbatim in the source · abstract, characters 108–281 · show in text ↑
Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

All tested related compounds except VI inhibited Sesamum seeds.

Taxon
Sesamum indicum L.Sesamum indicume0
Organ / stage
seedse0
Treatment
I-related compounds (II-V and VII-X) except for VIe0
Outcome
inhibitory activity on the seedse0
Direction
inhibitorye0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Sesamum indicum
Sesamum indicum · TaxonFranz Xaver · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“all of the I-related compounds (II-V and VII-X) except for VI, showed more or less obvious inhibitory activity on the seeds of Sesamum indicum L.”

✓ located verbatim in the source · abstract, characters 295–440 · show in text ↑
Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Compounds VII-X inhibited plant growth more strongly than compound I.

Taxon
phytogrowthe0
Treatment
Compounds VII-Xe0
Outcome
phytogrowth-inhibitory activitye0
Direction
more potente0
Comparator
Ie0

Verbatim

e0

“Compounds VII-X, in which the carboxyl group of I was replaced by acetic acid, propionic acid, butyric acid and acrylic acid, and exhibited more potent phytogrowth-inhibitory activity than I.”

✓ located verbatim in the source · abstract, characters 441–632 · show in text ↑
Observationobservedoriginal resultnegativemeasured

Claim · model-written summary

2-thiophenebutyric acid showed the strongest growth inhibition among the compounds.

Taxon
PhytoPhytot0
Treatment
2-thiophenebutyric acide0
Outcome
strongest activitye0
Direction
strongeste0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Phyto
Phyto · TaxonMichael Knapp · CC BY 4.0 · iNaturalist ↗

Verbatim

e0

“Among these compounds, 2-thiophenebutyric acid (IX) showed the strongest activity.”

✓ located verbatim in the source · abstract, characters 633–715 · show in text ↑
t0

“Phytogrowth-Inhibitory Activities”

✓ located verbatim in the source · title, characters 0–33 · show in text ↑
Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Esterification increased inhibitory activity relative to compound I.

Treatment
Esterificatione0
Outcome
inhibitory activitye0
Direction
increasede0
Comparator
Ie0

Not reportedTaxon

Verbatim

e0

“Esterification of the carboxyl group in I increased the inhibitory activity relative to that of I”

✓ located verbatim in the source · abstract, characters 716–813 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Amidation and reduction decreased inhibitory activity relative to compound I.

Taxon
PhytoPhytot0
Treatment
amidation and reductione0
Outcome
inhibitory activitye0
Direction
decreasede0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Phyto
Phyto · TaxonMichael Knapp · CC BY 4.0 · iNaturalist ↗

Verbatim

e0

“amidation and reduction of this group markedly decreased its inhibitory activity.”

✓ located verbatim in the source · abstract, characters 821–902 · show in text ↑
t0

“Phytogrowth-Inhibitory Activities”

✓ located verbatim in the source · title, characters 0–33 · show in text ↑
Observationobservedoriginal resultnegativemeasured

Claim · model-written summary

Radicles treated with the compounds except VI showed negative geotropism despite germination.

Taxon
plantsViridiplantaee0
Organ / stage
radiclese0
Treatment
each of the compounds except for VIe0
Outcome
negative geotropisme0

Not reportedDirection

Verbatim

e0

“The radicles of the plants treated with each of the compounds except for VI showed negative geotropism, even though germination occurred.”

✓ located verbatim in the source · abstract, characters 903–1040 · show in text ↑