Abstract
A germinating seedling undergoes skotomorphogenesis to emerge from the soil and reach for light. During this phase, the cotyledons are closed, and the hypocotyl elongates. Upon exposure to light, the seedling rapidly switches to photomorphogenesis by opening its cotyledons and suppressing hypocotyl elongation. The E3 ubiquitin ligase CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1) is critical for maintaining skotomorphogenesis. Here, we report that jasmonate (JA) suppresses hypocotyl elongation and stimulates cotyledon opening in etiolated seedlings, partially phenocopying cop1 mutants in the dark. We also find that JA stabilizes several COP1-targeted transcription factors in a COP1-dependent manner. RNA-seq analysis further defines a JA-light co-modulated and cop1-dependent transcriptome, which is enriched for auxin-responsive genes and genes participating in cell wall modification. JA suppresses COP1 activity through at least two distinct mechanisms: decreasing COP1 protein accumulation in the nucleus; and reducing the physical interaction between COP1 and its activator, SUPPRESSOR OF PHYTOCHROME A-105 1 (SPA1). Our work reveals that JA suppresses COP1 activity to stabilize COP1 targets, thereby inhibiting hypocotyl elongation and stimulating cotyledon unfolding in etiolated Arabidopsis seedlings.
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Claims 8
Claim · model-written summary
Jasmonate suppressed hypocotyl elongation in etiolated seedlings.
- Taxon
- Arabidopsis
Arabidopsist0 - Organ / stage
- etiolated seedlingse0
- Treatment
- jasmonate (JA)e0
- Outcome
- hypocotyl elongatione0
- Direction
- suppressese0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“jasmonate (JA) suppresses hypocotyl elongation and stimulates cotyledon opening in etiolated seedlings”
t0“Arabidopsis”
Claim · model-written summary
Jasmonate stimulated cotyledon opening in etiolated seedlings.
- Taxon
- ArabidopsisArabidopsist0
- Organ / stage
- etiolated seedlingse0
- Treatment
- jasmonate (JA)e0
- Outcome
- cotyledon openinge0
- Direction
- stimulatese0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“jasmonate (JA) suppresses hypocotyl elongation and stimulates cotyledon opening in etiolated seedlings”
t0“Arabidopsis”
Claim · model-written summary
Jasmonate stabilized several COP1-targeted transcription factors in a COP1-dependent manner.
- Taxon
- ArabidopsisArabidopsist0
- Treatment
- JAe0
- Gene
- COP1e0
- Outcome
- COP1-targeted transcription factorse0
- Direction
- stabilizese0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“JA stabilizes several COP1-targeted transcription factors in a COP1-dependent manner”
t0“Arabidopsis”
Claim · model-written summary
RNA-seq defined a JA-light co-modulated and cop1-dependent transcriptome.
- Taxon
- ArabidopsisArabidopsist0
- Outcome
- JA-light co-modulated and cop1-dependent transcriptomee0
- Comparator
- JA-lighte0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“RNA-seq analysis further defines a JA-light co-modulated and cop1-dependent transcriptome”
t0“Arabidopsis”
Claim · model-written summary
That transcriptome was enriched for auxin response and cell wall modification genes.
- Taxon
- ArabidopsisArabidopsist0
- Outcome
- auxin-responsive genes and genes participating in cell wall modificatione0
- Direction
- enrichede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“which is enriched for auxin-responsive genes and genes participating in cell wall modification”
t0“Arabidopsis”
Claim · model-written summary
Jasmonate decreased COP1 protein accumulation in the nucleus.
- Taxon
- ArabidopsisArabidopsist0
- Treatment
- JAe0
- Gene
- COP1e0
- Outcome
- COP1 protein accumulation in the nucleuse0
- Direction
- decreasinge0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“JA suppresses COP1 activity through at least two distinct mechanisms: decreasing COP1 protein accumulation in the nucleus”
t0“Arabidopsis”
Claim · model-written summary
Jasmonate reduced the physical interaction between COP1 and SPA1.
- Taxon
- ArabidopsisArabidopsist0
- Treatment
- JAe0
- Gene
- COP1e0
- Outcome
- physical interaction between COP1 and its activator, SUPPRESSOR OF PHYTOCHROME A-105 1 (SPA1)e0
- Direction
- reducinge0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“JA suppresses COP1 activity through at least two distinct mechanisms: decreasing COP1 protein accumulation in the nucleus; and reducing the physical interaction between COP1 and its activator, SUPPRESSOR OF PHYTOCHROME A-105 1 (SPA1)”
t0“Arabidopsis”
Claim · model-written summary
The authors conclude that jasmonate suppresses COP1 activity to stabilize its targets and alter seedling morphogenesis.
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“JA suppresses COP1 activity to stabilize COP1 targets, thereby inhibiting hypocotyl elongation and stimulating cotyledon unfolding in etiolated Arabidopsis seedlings”
t0“Arabidopsis”
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