Abstract
Bioassay-guided sequential extraction of the seeds of Persicaria lapathifolia followed by chromatographic separations resulted in the identification of three chalcones; flavokawain B (1), pinostrobin chalcone (2) and pashanone (3). The structures of the isolated compounds were established based on NMR and MS spectroscopic data. Disk diffusion method was employed to evaluate the antibacterial and antifungal activities of the isolated compounds against two bacterial and four fungal strains. The chloroform extract and the compounds demonstrated significant antibacterial activities. Compound 2 showed the highest activity against Staphylococccus aureus bacterial strain and Trichoderma spp fungal strain. Its antifungal activity (22 mm) against Trichoderma spp is even greater than that of the reference drug, clotrimazole (20 mm).
Abstract from the paper’s OpenAlex record, shown for indexing and research. Copyright remains with the authors or the publisher. Read at the source ↗
The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.
Claims 4
Claim · model-written summary
Three chalcones (flavokawain B, pinostrobin chalcone and pashanone) were identified from Persicaria lapathifolia seeds.
- Taxon
- Persicaria lapathifolia
Persicaria lapathifoliae1 - Organ / stage
- seedse1
- Compound
- flavokawain Be2
- Outcome
- three chalconese2
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“Bioassay-guided sequential extraction of the seeds of Persicaria lapathifolia”
e2“resulted in the identification of three chalcones; flavokawain B (1), pinostrobin chalcone (2) and pashanone (3)”
Claim · model-written summary
The chloroform extract and the isolated compounds of Persicaria lapathifolia seeds showed significant antibacterial activity.
- Taxon
- Persicaria lapathifoliaPersicaria lapathifoliae1
- Material
- chloroform extracte3
- Outcome
- antibacterial activitiese3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“Bioassay-guided sequential extraction of the seeds of Persicaria lapathifolia”
e3“The chloroform extract and the compounds demonstrated significant antibacterial activities”
Claim · model-written summary
Pinostrobin chalcone (compound 2) showed the highest activity against Staphylococccus aureus among the tested compounds.
- Taxon
- Persicaria lapathifoliaPersicaria lapathifoliae1
- Interactor
- Staphylococccus aureuse4other
- Compound
- pinostrobin chalconee2
- Outcome
- highest activitye4
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“Bioassay-guided sequential extraction of the seeds of Persicaria lapathifolia”
e2“resulted in the identification of three chalcones; flavokawain B (1), pinostrobin chalcone (2) and pashanone (3)”
e4“Compound 2 showed the highest activity against Staphylococccus aureus bacterial strain and Trichoderma spp fungal strain”
Claim · model-written summary
Antifungal activity of compound 2 against Trichoderma spp (22 mm) was greater than that of clotrimazole (20 mm).
- Taxon
- Persicaria lapathifoliaPersicaria lapathifoliae1
- Treatment
- Compound 2e4
- Interactor
- Trichoderma spp
Trichodermae5other - Outcome
- antifungal activitye5
- Direction
- greatere5
- Value
- 22 mme5
- Comparator
- clotrimazolee5
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“Bioassay-guided sequential extraction of the seeds of Persicaria lapathifolia”
e4“Compound 2 showed the highest activity against Staphylococccus aureus bacterial strain and Trichoderma spp fungal strain”
e5“Its antifungal activity (22 mm) against Trichoderma spp is even greater than that of the reference drug, clotrimazole (20 mm)”