Abstract
Penoxsulam is a new sulfonamide herbicide used on rice crops for annual grasses, broadleaf weeds, and sedges control, either grown through transplanting or direct dry or direct seeding methods of planting. In this study, Allium cepa ana-telophase and comet assay were used to examine the cyto-genotoxic effects of herbicide penoxsulam on A. cepa roots. A. cepa bulbs were exposed to ½xEC50 (12.5 µg/L), EC50 (25 µg/L) and 2xEC50 (50 µg/L) concentrations of penoxsulam for 24, 48, 72 and 96 h. Distilled water and 10 ppm of methyl methanesulfonate (MMS) were used as negative and positive control groups, respectively. Penoxsulam showed a cytotoxic effect by reducing root growth and mitotic index (MI), a genotoxic effect because it statistically increased chromosome aberrations (CAs, anaphase bridge, chromosomal laggards, polyploidy, disturbed ana-telophase and stickiness) and DNA damage as compared to control. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) was also used for quantitative analysis of penoxsulam in A. cepa root meristem cells. Further molecular toxicological evaluations associated in the cyto-genotoxicity of penoxsulam on plants are needed to confirm these results
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Claims 4
Claim · model-written summary
Penoxsulam reduced root growth relative to control.
- Taxon
- Allium cepa L.
Allium cepat0 - Organ / stage
- Root Meristem Cellst0
- Treatment
- Penoxsulame0
- Outcome
- root growthe0
- Direction
- reducinge0
- Comparator
- controle0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Penoxsulam showed a cytotoxic effect by reducing root growth and mitotic index (MI), a genotoxic effect because it statistically increased chromosome aberrations (CAs, anaphase bridge, chromosomal laggards, polyploidy, disturbed ana-telophase and stickiness) and DNA damage as compared to control.”
t0“Allium cepa L. Root Meristem Cells”
Claim · model-written summary
Penoxsulam reduced mitotic index relative to control.
- Taxon
- Allium cepa L.Allium cepat0
- Treatment
- Penoxsulame0
- Outcome
- mitotic index (MI)e0
- Direction
- reducinge0
- Comparator
- controle0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Penoxsulam showed a cytotoxic effect by reducing root growth and mitotic index (MI), a genotoxic effect because it statistically increased chromosome aberrations (CAs, anaphase bridge, chromosomal laggards, polyploidy, disturbed ana-telophase and stickiness) and DNA damage as compared to control.”
t0“Allium cepa L. Root Meristem Cells”
Claim · model-written summary
Penoxsulam increased chromosome aberrations relative to control.
- Taxon
- Allium cepa L.Allium cepat0
- Treatment
- Penoxsulame0
- Outcome
- chromosome aberrationse0
- Direction
- increasede0
- Comparator
- controle0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Penoxsulam showed a cytotoxic effect by reducing root growth and mitotic index (MI), a genotoxic effect because it statistically increased chromosome aberrations (CAs, anaphase bridge, chromosomal laggards, polyploidy, disturbed ana-telophase and stickiness) and DNA damage as compared to control.”
t0“Allium cepa L. Root Meristem Cells”
Claim · model-written summary
Penoxsulam increased DNA damage relative to control.
- Taxon
- Allium cepa L.Allium cepat0
- Treatment
- Penoxsulame0
- Outcome
- DNA damagee0
- Direction
- increasede0
- Comparator
- controle0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Penoxsulam showed a cytotoxic effect by reducing root growth and mitotic index (MI), a genotoxic effect because it statistically increased chromosome aberrations (CAs, anaphase bridge, chromosomal laggards, polyploidy, disturbed ana-telophase and stickiness) and DNA damage as compared to control.”
t0“Allium cepa L. Root Meristem Cells”
The same questions in other papers
Penoxsulam · growth · Allium cepa (onion)Results agree
1 paper in the same direction as this paper
- negative
Penoxsulam · cytology · Allium cepa (onion)Results agree
1 paper in the same direction as this paper
- negative
Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.