Paper · 2019 · Frontiers in Plant Science

Omeprazole Treatment Enhances Nitrogen Use Efficiency Through Increased Nitrogen Uptake and Assimilation in Corn

Michael James Van Oosten; Emilia Dell’Aversana; Alessandra Ruggiero; et al.

8
claims
14
verbatim quotes
39
citations
1
research areas
✓
Open access · cc-by

Abstract

-ATPase of gastric parietal cells. Omeprazole has been recently shown to act as a plant growth regulator and enhancer of salt stress tolerance. Here, we report that omeprazole treatment in hydroponically grown maize improves nitrogen uptake and assimilation. The presence of micromolar concentrations of omeprazole in the nutrient solution alleviates the chlorosis and growth inhibition induced by low nitrogen availability. Nitrate uptake and assimilation is enhanced in omeprazole treated plants through changes in nitrate reductase activity, primary metabolism, and gene expression. Omeprazole enhances nitrate assimilation through an interaction with nitrate reductase, altering its activation state and affinity for nitrate as a substrate. Omeprazole and its targets represent a novel method for enhancing nitrogen use efficiency in plants.

Abstract from the paper’s OpenAlex record; open copy licensed cc-by. Read at the source ↗

The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.

Claims 8

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Omeprazole treatment improves nitrogen uptake in hydroponically grown maize.

Taxon
maizeZea mayse0
Treatment
omeprazole treatmente0
Outcome
nitrogen uptakee0
Direction
improvese0
Setting
hydroponically growne0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Zea mays
Zea mays · TaxonAkwugo · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“omeprazole treatment in hydroponically grown maize improves nitrogen uptake and assimilation.”

✓ located verbatim in the source · abstract, characters 165–258 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Omeprazole treatment improves nitrogen assimilation in hydroponically grown maize.

Taxon
maizeZea mayse0
Treatment
omeprazole treatmente0
Outcome
nitrogen uptake and assimilatione0
Direction
improvese0
Setting
hydroponically growne0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Zea mays
Zea mays · TaxonAkwugo · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“omeprazole treatment in hydroponically grown maize improves nitrogen uptake and assimilation.”

✓ located verbatim in the source · abstract, characters 165–258 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Micromolar omeprazole in nutrient solution alleviates chlorosis induced by low nitrogen availability.

Treatment
micromolar concentrations of omeprazole in the nutrient solutione0
Outcome
chlorosise0
Direction
alleviatese0
Qualifier
low nitrogen availabilitye0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Zea mays subsp. mays
Zea mays subsp. mays · TaxonDominicus Johannes Bergsma · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“The presence of micromolar concentrations of omeprazole in the nutrient solution alleviates the chlorosis and growth inhibition induced by low nitrogen availability.”

✓ located verbatim in the source · abstract, characters 259–424 · show in text ↑
t0

“Corn”

✓ located verbatim in the source · title, characters 108–112 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Micromolar omeprazole in nutrient solution alleviates growth inhibition induced by low nitrogen availability.

Treatment
micromolar concentrations of omeprazole in the nutrient solutione0
Outcome
growth inhibitione0
Direction
alleviatese0
Qualifier
low nitrogen availabilitye0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Zea mays subsp. mays
Zea mays subsp. mays · TaxonDominicus Johannes Bergsma · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“The presence of micromolar concentrations of omeprazole in the nutrient solution alleviates the chlorosis and growth inhibition induced by low nitrogen availability.”

✓ located verbatim in the source · abstract, characters 259–424 · show in text ↑
t0

“Corn”

✓ located verbatim in the source · title, characters 108–112 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Omeprazole enhances nitrate uptake in treated plants.

Treatment
omeprazolee0
Outcome
Nitrate uptakee0
Direction
enhancede0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Zea mays subsp. mays
Zea mays subsp. mays · TaxonDominicus Johannes Bergsma · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“Nitrate uptake and assimilation is enhanced in omeprazole treated plants through changes in nitrate reductase activity, primary metabolism, and gene expression.”

✓ located verbatim in the source · abstract, characters 425–585 · show in text ↑
t0

“Corn”

✓ located verbatim in the source · title, characters 108–112 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Omeprazole enhances nitrate assimilation in treated plants.

Treatment
omeprazolee0
Outcome
Nitrate uptake and assimilatione0
Direction
enhancede0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Zea mays subsp. mays
Zea mays subsp. mays · TaxonDominicus Johannes Bergsma · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“Nitrate uptake and assimilation is enhanced in omeprazole treated plants through changes in nitrate reductase activity, primary metabolism, and gene expression.”

✓ located verbatim in the source · abstract, characters 425–585 · show in text ↑
t0

“Corn”

✓ located verbatim in the source · title, characters 108–112 · show in text ↑
Mechanismauthor interpretationoriginal resultpositivemeasured

Claim · model-written summary

Omeprazole enhances nitrate assimilation through interaction with nitrate reductase and changes to its activation state and nitrate affinity.

Treatment
Omeprazolee0
Gene
nitrate reductasee0
Outcome
nitrate assimilatione0
Direction
enhancese0
Qualifier
altering its activation state and affinity for nitrate as a substratee0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Zea mays subsp. mays
Zea mays subsp. mays · TaxonDominicus Johannes Bergsma · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“Omeprazole enhances nitrate assimilation through an interaction with nitrate reductase, altering its activation state and affinity for nitrate as a substrate.”

✓ located verbatim in the source · abstract, characters 586–744 · show in text ↑
t0

“Corn”

✓ located verbatim in the source · title, characters 108–112 · show in text ↑
Recommendationauthor interpretationoriginal resultpositivebasis n/a

Claim · model-written summary

The authors propose omeprazole and its targets as a method for enhancing plant nitrogen use efficiency.

Treatment
Omeprazolee0
Outcome
enhancing nitrogen use efficiencye0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Zea mays subsp. mays
Zea mays subsp. mays · TaxonDominicus Johannes Bergsma · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“Omeprazole and its targets represent a novel method for enhancing nitrogen use efficiency in plants.”

✓ located verbatim in the source · abstract, characters 745–845 · show in text ↑
t0

“Corn”

✓ located verbatim in the source · title, characters 108–112 · show in text ↑

fertilization · disease · Zea mays (maize)Results differ

84 papers: 56 positive, 28 negative or no effect

55 papers in the same direction as this paper · 28 in the opposite direction

  1. negative
  2. negative
  3. negative
    Conventionally treated fields had more Diplodia stalk rot.

    Maize Yields and Soil Nutrient Levels With and Without Pesticides and Standard Commercial Fertilizers1 · 1980 · compared with no herbicides, insecticides, or standard commercial fertilizers

    Opposite direction

80 papers more in this group

See all 84 papers →

fertilization · physiology: pigments · Zea mays (maize)Positive and negative results

171 papers: 157 positive, 14 negative or no effect

156 papers in the same direction as this paper · 11 in the opposite direction · 3 reporting no difference from an alternative

  1. no effect
  2. no effect
  3. no effect

167 papers more in this group

See all 171 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.