Claim · model-written summary
Methanol extracts of both species showed noteworthy or moderate average MIC activity against E. coli, M. catarrhalis and S. agalactiae.
- Taxon
- Helichrysum odoratissimum and Helichrysum petiolare
Helichrysum odoratissimum
Helichrysum petiolaret0 - Treatment
- methanol extractse6
- Interactor
- E. coli
Escherichia colie6pathogen - Second interactor
- M. catarrhalis
Moraxella catarrhalise6pathogen - Outcome
- average MICs denoting noteworthy or moderate activitye6
- Qualifier
- S. agalactiaee6
Verbatim
e6“The methanol extracts yielded average MICs denoting noteworthy or moderate activity towards three pathogens (E. coli, M. catarrhalis and S. agalactiae)”
t0“Helichrysum odoratissimum and Helichrysum petiolare”
Title
Khotso Serabele; Weiyang Chen; Sidonie Tankeu; et al. South African Journal of Botany 2020. doi:10.1016/j.sajb.2020.09.023
Other claims from this paper (14)
- Observation Three isomeric compounds were present in both Helichrysum species.
- Observation Chemometric models showed a large degree of inter-population variation within H. odoratissimum, with samples loosely clustering into two main groups.
- Observation The chemistry of H. petiolare was highly conserved.
- Observation Discriminant analysis identified four distinguishing marker compounds for each species.
- Observation A common isomer isolated from H. odoratissimum was identified as 4,5-dicaffeoylquinic acid by NMR and is reported for the first time from the two species.
- Observation The concentration of the compound in H. odoratissimum ranged from 3.89 to 31.1 µg/g.
- Observation The concentration of the compound in H. petiolare ranged from 2.3 to 13.4 µg/g.
- Observation HPTLC fingerprints indicated a greater degree of chemical variation within H. odoratissimum than within H. petiolare.
- Method / resource Multivariate analysis of HPTLC densitograms confirmed the chemical variation pattern and mirrored the UPLC-MS results.
- Intervention effect Extracts of H. odoratissimum were more effective against a larger range of bacteria than extracts of H. petiolare.
- Observation Chloroform:methanol extracts showed noteworthy or moderate activity against the same three pathogens and also against E. faecalis.
- Observation UPLC-PDA profiles of smoke condensates of both species revealed five major compounds common to both species.
- Observation The smoke profiles of the two species were similar.
- Observation Solvent extracts of the two species showed little congruence in chemical profiles or antibacterial activities.
