By interacting organism › Other organisms › Hexamitidae

Observationobservedoriginal resultmeasured

Claim · model-written summary

Papaucin showed moderate positive in vitro activity against Giardia lamblia with an IC50 of 67.62 μg/mL.

Taxon: Annona diversifoliaAnnona diversifoliat0
Interactor: Giardia lambliaGiardia duodenalise1other
Outcome: IC 50 valuese0
Value: 67.62 μg mL −1e0

Verbatim

t0
“Annona diversifolia”
✓ located verbatim in the source · title, characters 66–85

e0
“IC 50 values of 63.07 and 67.62 μg mL −1”
✓ located verbatim in the source · abstract, characters 586–626

e1
“Giardia lamblia”
✓ located verbatim in the source · abstract, characters 563–578

Title

Structural Elucidation of the Cyclopeptide Papaucin Isolated From Annona diversifolia Saff. Seeds by NMR, Antiprotozoal Activity and Molecular Docking Studies

Ulises Murrieta‐Dionicio; Fernando Calzada; Elizabeth Barbosa; et al. Magnetic Resonance in Chemistry 2025. doi:10.1002/mrc.70065

Other claims from this paper (5)

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

The assay simultaneously detected C. parvum and G. duodenalis on lettuce, among other protozoa.

Taxon: LettuceLactuca sativae1
Interactor: C. parvumCryptosporidium parvume4other
Second interactor: G. duodenalisGiardia duodenalise4other
Outcome: simultaneous detectione4
Qualifier: C. hominis, C. muris, G. duodenalis and T. gondiie4

Verbatim

e1
“Lettuce (25 g) was spiked with varying numbers of Cryptosporidium parvum oocysts”
✓ located verbatim in the source · abstract, characters 575–655

e4
“The assay proved useful for the simultaneous detection of C. parvum, C. hominis, C. muris, G. duodenalis and T. gondii”
✓ located verbatim in the source · abstract, characters 1812–1930

Title

Metagenomic detection of protozoan parasites on leafy greens aided by a rapid and efficient DNA extraction protocol

Sohail Naushad; Ruimin Gao; Marc-Olivier Duceppe; et al. Frontiers in Microbiology 2025. doi:10.3389/fmicb.2025.1566579

Other claims from this paper (4)

Method / resource The mNGS assay identified as few as 100 oocysts of C. parvum in 25 g of fresh lettuce.
Method / resource Ion S5 sequencing gave results similar to Nanopore sequencing for the mNGS assay on lettuce.
Method / resource Amplification gave 0.16–8.25 μg of DNA from lettuce washes, sufficient to perform mNGS.
Method / resource Lysis of oocysts and cysts was rapidly achieved within 3 min on lettuce, a prerequisite for sensitive detection.

Intervention effectobservedoriginal resultmeasured

Claim · model-written summary

Exposure of Arabidopsis leaves to Cryptosporidia or Giardia caused large changes in gene expression that overlapped between the two parasites.

Taxon: ArabidopsisArabidopsise1
Treatment: heat-inactivated Cryptosporidia or Giardiae1
Interactor: Cryptosporidiae1other
Second interactor: GiardiaGiardiae1other
Outcome: gene expressione2

Not reportedComparatorDirection

Verbatim

e1
“Detached Arabidopsis leaves were exposed for one hour to heat-inactivated Cryptosporidia or Giardia”
✓ located verbatim in the source · abstract, characters 551–650

e2
“The transcriptome profile showed large changes in gene expression with significant overlap between two parasites”
✓ located verbatim in the source · abstract, characters 652–764

Title

Transcriptome of Arabidopsis thaliana Plants Exposed to Human Parasites Cryptosporidium parvum and Giardia lamblia

Yaroslav Ilnytskyy; Andrey Golubov; Boseon Byeon; et al. International Journal of Plant Biology 2025. doi:10.3390/ijpb16010013

Other claims from this paper (4)

Observationobservedoriginal resultmeasured

Claim · model-written summary

Upregulated GO terms were found in Arabidopsis leaves exposed to the parasites, including defense and wounding responses.

Taxon: ArabidopsisArabidopsise1
Interactor: Cryptosporidiae1other
Second interactor: GiardiaGiardiae1other
Outcome: upregulated GO termse3
Direction: upregulatede3

Verbatim

e1
“Detached Arabidopsis leaves were exposed for one hour to heat-inactivated Cryptosporidia or Giardia”
✓ located verbatim in the source · abstract, characters 551–650

e3
“including upregulated GO terms”
✓ located verbatim in the source · abstract, characters 766–796

Title

Transcriptome of Arabidopsis thaliana Plants Exposed to Human Parasites Cryptosporidium parvum and Giardia lamblia

Yaroslav Ilnytskyy; Andrey Golubov; Boseon Byeon; et al. International Journal of Plant Biology 2025. doi:10.3390/ijpb16010013

Other claims from this paper (4)

Observationobservedoriginal resultmeasured

Claim · model-written summary

Downregulated GO terms were found in Arabidopsis leaves exposed to the parasites, including development and cell surface terms.

Taxon: ArabidopsisArabidopsise1
Interactor: Cryptosporidiae1other
Second interactor: GiardiaGiardiae1other
Outcome: downregulated GO termse4
Direction: downregulatede4

Verbatim

e1
“Detached Arabidopsis leaves were exposed for one hour to heat-inactivated Cryptosporidia or Giardia”
✓ located verbatim in the source · abstract, characters 551–650

e4
“and downregulated GO terms”
✓ located verbatim in the source · abstract, characters 979–1005

Title

Transcriptome of Arabidopsis thaliana Plants Exposed to Human Parasites Cryptosporidium parvum and Giardia lamblia

Yaroslav Ilnytskyy; Andrey Golubov; Boseon Byeon; et al. International Journal of Plant Biology 2025. doi:10.3390/ijpb16010013

Other claims from this paper (4)

Hexamitidae 5 claims

5 claims