Intervention effectmodel-written summary

Disruption of pmeR reduced bacterial growth in Arabidopsis thaliana.

A claim from PmeR, a TetR-like transcriptional regulator, is involved in both auxin signaling and virulence in the plant pathogen Pseudomonas syringae strain Pto DC3000 · 2025

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Disruption of pmeR reduced bacterial growth in Arabidopsis thaliana.

Taxon
Arabidopsis thalianaArabidopsis thalianae0
Treatment
disruption of pmeRe0
Interactor
Pto DC3000e7pathogen
Gene
pmeRe0
Outcome
bacterial growthe0
Direction
reducede0

Not reportedMaterialCompoundOrgan / stageSecond interactorSecond interactor roleComparatorSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Arabidopsis thaliana
Arabidopsis thaliana · TaxonOriginal uploader was Brona at en.wikipedia . User:Roepers at nl.wikipedia · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“disruption of pmeR results in reduced bacterial growth in Arabidopsis thaliana”

✓ located verbatim in the source · abstract, characters 1025–1103
e7

“gene expression in Pto DC3000.”

✓ located verbatim in the source · abstract, characters 667–697

Title

PmeR, a TetR-like transcriptional regulator, is involved in both auxin signaling and virulence in the plant pathogen Pseudomonas syringae strain Pto DC3000

Chia-Yun Lee; Maya Irvine; Barbara Kunkel mBio 2025. doi:10.1128/mbio.01152-25

Other claims from this paper (6)

Record rev-3ce2af1323f61353e8f02de019d80f638269e62229fee2880c360e74918a6bda · schema claims-v0.9 · position 5 in the model’s answer

loss of function · disease · Arabidopsis thaliana (thale cress)Positive and negative results

82 papers: 31 positive, 51 negative or no effect

50 papers in the same direction as this claim · 31 in the opposite direction

  1. positive
    Disruption of aldA and aldB reduced virulence on A. thaliana.

    Indole-3-acetaldehyde dehydrogenase-dependent auxin synthesis contributes to virulence of Pseudomonas syringae strain DC3000 · 2018

    Opposite directionCited by this paper

  2. positive
    Mutations in toxA, plcS and gacA significantly reduced UCBPP-PA14 pathogenicity in both Arabidopsis and mouse hosts.

    Common Virulence Factors for Bacterial Pathogenicity in Plants and Animals · 1995

    Opposite direction

  3. positive
    hkt1 mutations abolished the growth inhibition of sos3-1 caused by K(+) deficiency in low-Ca(2+) medium.

    AtHKT1 is a salt tolerance determinant that controls Na + entry into plant roots · 2001

    Opposite direction

  4. positive
    PHF1 mutation increased arsenate resistance.

    PHOSPHATE TRANSPORTER TRAFFIC FACILITATOR1 Is a Plant-Specific SEC12-Related Protein That Enables the Endoplasmic Reticulum Exit of a High-Affinity Phosphate Transporter in Arabidopsis  [W] · 2005

    Opposite direction

  5. positive
    A CTR2 mutation increased yeast resistance to toxic copper.

    Molecular Characterization of a Putative Arabidopsis thaliana Copper Transporter and Its Yeast Homologue · 1995

    Opposite direction

  6. positive
    SAMDC1 loss of function reduced BSCTV susceptibility.

    BSCTV C2 Attenuates the Degradation of SAMDC1 to Suppress DNA Methylation-Mediated Gene Silencing in Arabidopsis    · 2011

    Opposite direction

  7. positive
    AtNIP7;1 loss of function increased Arabidopsis tolerance to AsIII.

    The Arabidopsis thaliana aquaglyceroporin AtNIP7;1 is a pathway for arsenite uptake · 2008

    Opposite direction

  8. positive
    Arabidopsis thaliana RNA interference-PARP lines were more resistant to abiotic stress.

    Silencing of poly(ADP-ribose) polymerase in plants alters abiotic stress signal transduction · 2007

    Opposite direction

73 papers more in this group

See all 82 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.

Functional evidence on pmeR

Claims that state a gain or loss of function of this gene and what it did to a trait, compared with wild type or a control.

pmeR

Arabidopsis thaliana (thale cress)1 paper · 1 traitTested in one paper only

Only one paper in the store tests this gene's function in Arabidopsis thaliana (thale cress).

Disease resistance1 paper

  1. Restrains
    Disruption of pmeR reduced bacterial growth in Arabidopsis thaliana.

    PmeR, a TetR-like transcriptional regulator, is involved in both auxin signaling and virulence in the plant pathogen Pseudomonas syringae strain Pto DC3000 · 2025

    loss of function → more of the traitThis claim

The program reads each claim's manipulation and the direction of the trait, and from them the gene's role (gain and more, or loss and less, means it promotes the trait). Roles are read by program from each claim's wording. Pairs of papers on the same host, gene and trait were checked claim by claim by two model readers; a pair is marked checked only when both accept it. Gene layer v0.8, 21 trait classes.