Claim · model-written summary
Bundling and subsequent breakdown of actin followed the YVADase activity during perforation formation.
- Taxon
- Aponogeton madagascariensis
Aponogeton madagascariensise2 - Outcome
- bundling and subsequent breakdown of actine1
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e2“Aponogeton madagascariensis produces perforations over its leaf surface via programmed cell death (PCD)”
e1“Results depicted that YVADase (caspase-1) activity is higher during the very early stages of perforation formation, followed by the bundling and subsequent breakdown of actin”
Title
Christina E. N. Lord; Adrian N. Dauphinee; Rebecca L. Watts; et al. PLoS ONE 2013. doi:10.1371/journal.pone.0057110
Other claims from this paper (7)
- Observation YVADase (caspase-1) activity was higher in the very early stages of perforation formation.
- Intervention effect Actin depolymerization with Lat B caused no change in YVADase activity.
- Intervention effect In vivo inhibition of YVADase activity prevented PCD and actin breakdown.
- Intervention effect The mitochondrial pore inhibitor CsA significantly decreased YVADase activity.
- Intervention effect The mitochondrial pore inhibitor CsA prevented PCD and actin breakdown.
- Mechanism Mitochondria may be a possible trigger for caspase-like proteases during PCD in the lace plant.
- Mechanism Actin is likely a substrate for caspase-like proteases (CLPs) during PCD.