Claim · model-written summary
PARP1 suppression increased expression of NbCAT2.
- Taxon
- N. benthamiana
Nicotiana benthamianae0 - Treatment
- RNA silencing of the PARP1 genee0
- Gene
- NbCAT2e1
- Outcome
- gene expressione1
- Direction
- increasede1
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the burst of reactive oxygen species (ROS), cell death, and loss of tissue viability invoked by MV in N. benthamiana leaves was significantly delayed by both the RNA silencing of the PARP1 gene and by applying the pharmacological inhibitor 3-aminobenzamide (3AB) to inhibit PARylation activity”
e1“This in turn reduced the accumulation of PARylated proteins and significantly increased the gene expression of major ROS scavenging enzymes including SOD (NbMnSOD; mitochondrial manganese SOD), CAT (NbCAT2), GR (NbGR), and APX (NbAPX5), and inhibited cell death”
Title
Natalia O. Kalinina; Nadezhda Spechenkova; Irina Ilina; et al. International Journal of Molecular Sciences 2024. doi:10.3390/ijms25179367
Other claims from this paper (10)
- Intervention effect RNA silencing of the PARP1 gene delayed burst of reactive oxygen species (ROS).
- Intervention effect RNA silencing of the PARP1 gene delayed cell death.
- Intervention effect RNA silencing of the PARP1 gene delayed loss of tissue viability.
- Intervention effect applying the pharmacological inhibitor 3-aminobenzamide (3AB) delayed burst of reactive oxygen species (ROS).
- Intervention effect applying the pharmacological inhibitor 3-aminobenzamide (3AB) delayed cell death.
- Intervention effect applying the pharmacological inhibitor 3-aminobenzamide (3AB) delayed loss of tissue viability.
- Intervention effect PARP1 suppression reduced PARylated protein accumulation.
- Intervention effect PARP1 suppression increased expression of NbMnSOD.
- Intervention effect PARP1 suppression increased expression of NbGR.
- Intervention effect PARP1 suppression increased expression of NbAPX5.