Claim · model-written summary
GmEF1A silencing inhibits SMV accumulation.
- Taxon
- soybean
Glycine maxe0 - Treatment
- Silencing GmEF1Ae0
- Interactor
- SMVe0pathogen
- Gene
- GmEF1Ae0
- Outcome
- accumulation of SMVe0
- Direction
- inhibitse0
Not reportedMaterialCompoundOrgan / stageSecond interactorSecond interactor roleComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Silencing GmEF1A inhibits accumulation of SMV and another ER-associated virus in soybean”
Title
Hexiang Luan; M.B. Shine; Xiaoyan Cui; et al. PLANT PHYSIOLOGY 2016. doi:10.1104/pp.16.00505
Other claims from this paper (9)
- Observation SMV P3 targets a translation elongation complex component in soybean.
- Mechanism eEF1A is essential for SMV virulence and the associated UPR.
- Intervention effect GmEF1A silencing also inhibits another ER-associated virus.
- Intervention effect ER stress chemicals promote SMV accumulation in wild-type plants.
- Intervention effect ER stress chemicals did not promote SMV accumulation in GmEF1A knockdown plants.
- Intervention effect eEF1B knockdown similarly affected UPR and SMV resistance.
- Association P3 and GmEF1A promote each other’s nuclear localization.
- Mechanism The authors infer that P3 targets host elongation factors to induce UPR and aid SMV replication.
- Mechanism eEF1A was placed upstream of BiP in the infection-associated ER stress response.