Intervention effectmodel-written summary

Silencing TaCYP72A caused more DON-induced discoloration of wheat spikelets than mock silencing.

A claim from A wheat cytochrome P450 enhances both resistance to deoxynivalenol and grain yield · 2018

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Silencing TaCYP72A caused more DON-induced discoloration of wheat spikelets than mock silencing.

Treatment
VIGSe0
Gene
TaCYP72Ae1
Outcome
DON-induced discoloration of spikeletse0
Direction
moree0
Comparator
mock VIGS treatmente0

Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

t0

“wheat”

✓ located verbatim in the source · title, characters 2–7
e1

“TaCYP72A also had a positive effect on grain number.”

✓ located verbatim in the source · abstract, characters 911–963
e0

“VIGS resulted in more DON-induced discoloration of spikelets, as compared to mock VIGS treatment.”

✓ located verbatim in the source · abstract, characters 761–858

Title

A wheat cytochrome P450 enhances both resistance to deoxynivalenol and grain yield

Lokanadha R. Gunupuru; Chanemougasoundharam Arunachalam; Keshav B. Malla; et al. PLoS ONE 2018. doi:10.1371/journal.pone.0204992

Other claims from this paper (5)

Record rev-7e44607fb45bfa597a899918489ba09d372dde491bf9e7c7d282721d0390dcfc · schema claims-v0.9 · position 4 in the model’s answer

loss of function · disease · Triticum aestivum (wheat)Positive and negative results

177 papers: 81 positive, 96 negative or no effect

95 papers in the same direction as this claim · 81 in the opposite direction

  1. negative
    Silencing two TaSnRK1α homoeolog groups increased DON-induced wheat spikelet damage.

    The wheat SnRK1α family and its contribution to Fusarium toxin tolerance · 2019

    Same directionCites this paper

  2. negative
    Silencing TaMPT increased susceptibility of CM82036 to head blight.

    Mitochondrial phosphate transporter and methyltransferase genes contribute to Fusarium head blight Type II disease resistance and grain development in wheat · 2021

    Same directionCites this paper

  3. positive
    Silencing TaEDR1 increased wheat resistance to powdery mildew.

    Simultaneous modification of three homoeologs of TaEDR1 by genome editing enhances powdery mildew resistance in wheat · 2017

    Opposite direction

  4. positive
    Silencing TaISP by virus-induced gene silencing in a susceptible wheat cultivar reduces fungal growth and uredinium development.

    An effector protein of the wheat stripe rust fungus targets chloroplasts and suppresses chloroplast function · 2019

    Opposite direction

  5. positive
    Only the specific two amino acid deletion in WTK3 kinase I gave resistance against Bgt.

    A rare gain of function mutation in a wheat tandem kinase confers resistance to powdery mildew · 2020 · compared with single or more amino acid deletions

    Opposite direction

  6. positive
    Silencing the Pst-milR1 precursor increased wheat resistance to CYR31.

    Puccinia striiformis f. sp. tritici mi croRNA ‐like RNA 1 ( Pst ‐milR1), an important pathogenicity factor of Pst , impairs wheat resistance to Pst by suppressing the wheat pathogenesis‐related 2 gene · 2017

    Opposite direction

  7. positive
    The same breeding strategy gave a marked concomitant increase in resistant starch content in wheat.

    A genetic strategy generating wheat with very high amylose content · 2015

    Opposite direction

  8. positive
    TaNAC30 silencing inhibited colonization by CYR31.

    A novel wheat NAC transcription factor, TaNAC30, negatively regulates resistance of wheat to stripe rust · 2017

    Opposite direction

168 papers more in this group

See all 177 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.

Functional evidence on TaCYP72A

Claims that state a gain or loss of function of this gene and what it did to a trait, compared with wild type or a control.

TaCYP72A

Triticum aestivum (wheat)1 paper · 1 traitTested in one paper only

Only one paper in the store tests this gene's function in Triticum aestivum (wheat).

Yield1 paper

  1. Restrains
    Silencing TaCYP72A caused more DON-induced discoloration of wheat spikelets than mock silencing.

    A wheat cytochrome P450 enhances both resistance to deoxynivalenol and grain yield · 2018

    loss of function → more of the traitThis claim

  2. Promotes
    Silencing TaCYP72A reduced wheat grain number by more than 59%.

    A wheat cytochrome P450 enhances both resistance to deoxynivalenol and grain yield · 2018

    loss of function → less of the trait

The program reads each claim's manipulation and the direction of the trait, and from them the gene's role (gain and more, or loss and less, means it promotes the trait). Roles are read by program from each claim's wording. Pairs of papers on the same host, gene and trait were checked claim by claim by two model readers; a pair is marked checked only when both accept it. Gene layer v0.8, 21 trait classes.