Intervention effectmodel-written summary

Lead increased methylglyoxal.

A claim from Exogenous glutathione attenuates lead-induced oxidative stress in wheat by improving antioxidant defense and physiological mechanisms · 2018

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Lead increased methylglyoxal.

Treatment
Pb stresse0
Outcome
methylglyoxale0
Direction
increasee0

Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Triticum aestivum
Triticum aestivum · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“The increase of methylglyoxal was evident under Pb stress”

✓ located verbatim in the source · abstract, characters 516–573
t0

“wheat”

✓ located verbatim in the source · title, characters 66–71

Title

Exogenous glutathione attenuates lead-induced oxidative stress in wheat by improving antioxidant defense and physiological mechanisms

Mirza Hasanuzzaman; Kamrun Nahar; Anisur Rahman; et al. Journal of Plant Interactions 2018. doi:10.1080/17429145.2018.1458913

Other claims from this paper (8)

Record rev-8d04a2b021fbbe4c70dada726ca58aeca43a057c10e4cf1ef8339bcb085cf941 · schema claims-v0.9 · position 5 in the model’s answer

lead atom · molecular: metabolites · Triticum aestivum (wheat)Results agree

6 papers: 0 positive, 6 negative or no effect

5 papers in the same direction as this claim

  1. negative
    Pb stress increased chlorophyll degradation and OAS-TL activity in wheat seedlings.

    Ascorbic acid improves the tolerance of wheat plants to lead toxicity · 2018 · compared with control

    Same direction

  2. negative
    Lead accumulation in wheat seeds was 119% higher than in control plants.

    Effect of industrial wastewater on wheat germination, growth, yield, nutrients and bioaccumulation of lead · 2020 · compared with control plants

    Same direction

  3. negative
    Lead stress increased glutathione content in wheat leaves.

    Bioaccumulation of Lead and the Effects of Lead on Catalase Activity, Glutathione Levels, and Chlorophyll Content in the Leaves of Wheat · 2010

    Same direction

  4. negative
    Increasing soil Pb concentration increased its concentration in wheat biomass.

    PHYTOTOXIC EFFECTS OF RISING DOSES OF CHOSEN ELEMENTS IN INITIAL PHASES OF WHEAT GROWTH · 2001

    Same direction

  5. negative
    High Pb concentration impeded N, P and K accumulation.

    The Impact of Lead Stress on Growth and Development of Two Varieties of Wheat · 2010

    Same direction

See all 6 papers →

heavy metal · molecular: metabolites · Triticum aestivum (wheat)Positive and negative results

34 papers: 6 positive, 28 negative or no effect

27 papers in the same direction as this claim · 6 in the opposite direction

  1. positive
    Ascorbate content increased significantly under heavy metal treatment.

    Heavy Metals Induce Lipid Peroxidation and Affect Antioxidants in Wheat Leaves · 2003

    Opposite direction

  2. positive
    Pretreatment with NaHS enhanced the contents of AsA, GSH and total ascorbate under copper stress.

    Hydrogen sulfide protects wheat seedlings against copper stress by regulating the ascorbate and glutathione metabolism in leaves · 2012 · compared with copper stress

    Opposite direction

  3. positive
    Aluminum stress increased cysteine, glycine, and glutamic amino acids.

    Impacts of Aluminum on Growth and Biochemical Process of Wheat Plants Under Boron Treatments · 2018

    Opposite direction

  4. positive
    Selenium plus cadmium stress bolstered AsA/dehydroascorbic acid and GSH/oxidized glutathione ratios compared with cadmium stress alone.

    Selenium improves wheat antioxidant capacity, photosynthetic capacity, and growth under cadmium stress · 2024 · compared with CS

    Opposite direction

  5. positive
    With copper stress, spermidine increased DHAR activity to 3.77 U/g FW.

    Spermidine mitigates wheat copper toxicity by modulating ascorbate and glutathione metabolism, copper accumulation and photosynthetic performance · 2025 · compared with Cu stress

    Opposite direction

  6. positive
    Compared with Cd alone, PGA plus Cd stress reinforced AsA and GSH metabolism in wheat leaves.

    Poly-glutamic acid reinforces wheat cadmium tolerance by modulating ascorbic acid and glutathione metabolism · 2024 · compared with Cd alone

    Opposite direction

  7. no effect
    Al exposure did not affect inositol trisphosphate dephosphorylation.

    Aluminum Inhibition of the Inositol 1,4,5-Trisphosphate Signal Transduction Pathway in Wheat Roots: A Role in Aluminum Toxicity? · 1995

    Same direction

  8. negative
    Copper stress also lowered pheophytin content of wheat, showing the same pattern as chlorophyll.

    Response of wheat seed germination and seedling growth under copper stress. · 2007

    Same direction

25 papers more in this group

See all 34 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.