Intervention effectmodel-written summary

Transient FocRnt2 expression suppressed BAX-mediated cell death.

A claim from A ribonuclease T2 protein FocRnt2 contributes to the virulence of Fusarium oxysporum f. sp. cubense tropical race 4 · 2024

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Taxon: N. benthamianaNicotiana benthamianae0
Treatment: Transient expression of FocRnt2e0
Gene: FocRnt2e0
Outcome: BAX-mediated cell deathe0
Direction: suppressede0

Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

*Nicotiana benthamiana* · TaxonCharles Andres · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0
“Transient expression of FocRnt2 suppressed the expression of salicylic acid- and jasmonic acid-signalling marker genes, reactive oxygen species accumulation, and BAX-mediated cell death in N. benthamiana”
✓ located verbatim in the source · abstract, characters 875–1078

Title

A ribonuclease T2 protein FocRnt2 contributes to the virulence of Fusarium oxysporum f. sp. cubense tropical race 4

Yanqiu He; Pengfei Li; Xiaoshu Zhou; et al. Molecular Plant Pathology 2024. doi:10.1111/mpp.13502

Other claims from this paper (12)

Observation FocRnt2 expression was significant early in plant infection.
Observation FocRnt2 had a functional secretion signal peptide.
Observation FocRnt2 degraded banana total RNA in vitro.
Observation FocRnt2 localized in the nucleus and cytoplasm of Nicotiana benthamiana leaves.
Intervention effect Transient FocRnt2 expression suppressed salicylic acid and jasmonic acid signaling marker genes.
Intervention effect Transient FocRnt2 expression suppressed reactive oxygen species accumulation.
Intervention effect FocRnt2 deletion limited fungal penetration.
Intervention effect FocRnt2 deletion reduced fusaric acid biosynthesis in Foc TR4.
Intervention effect FocRnt2 deletion attenuated fungal virulence against banana.
Intervention effect FocRnt2 deletion had little effect on fungal growth and stress sensitivity.
Intervention effect Deletion mutants induced higher defense gene expression in banana.
Mechanism The authors interpret FocRnt2 as contributing to full Foc TR4 virulence.

Record rev-aedecec09e7cbb31f839787140c761c858ed6a54a8e6f9896fc5785ff22edceb · schema claims-v0.9 · position 7 in the model’s answer

transgenic · cytology · Nicotiana benthamianaPositive and negative results

42 papers: 14 positive, 28 negative or no effect

27 papers in the same direction as this claim · 14 in the opposite direction

negative
Transient Fg12 expression caused light-dependent cell death in Nicotiana benthamiana.
Fg12 ribonuclease secretion contributes to Fusarium graminearum virulence and induces plant cell death · 2020
Same directionCited by this paper
positive
Transient PR10 expression triggers cell death in Nicotiana benthamiana leaves.
Requirement of the Cytosolic Interaction between PATHOGENESIS-RELATED PROTEIN10 and LEUCINE-RICH REPEAT PROTEIN1 for Cell Death and Defense Signaling in Pepper · 2012
Opposite direction
positive
Modestly reducing Rep and RepA expression reduced leaf cell death.
Modifying the Replication of Geminiviral Vectors Reduces Cell Death and Enhances Expression of Biopharmaceutical Proteins in Nicotiana benthamiana Leaves · 2019
Opposite direction
positive
Transient Ha18764 expression suppressed several elicitor-related cell death responses in Nicotiana benthamiana.
A Novel G16B09-Like Effector From Heterodera avenae Suppresses Plant Defenses and Promotes Parasitism · 2019
Opposite direction
positive
Transient expression of fla Lso caused slow necrotic cell death and reactive oxygen species production in N. benthamiana leaves.
Induction of innate immune responses by flagellin from the intracellular bacterium, ‘CandidatusLiberibacter solanacearum’ · 2014
Opposite direction
positive
PstSIE1 expression suppressed VmE02- and PcNLP2-induced cell death in Nicotiana benthamiana.
A stripe rust fungal effector PstSIE1 targets TaSGT1 to facilitate pathogen infection · 2022
Opposite direction
positive
A silencing-resistant SlMai1 gene restored programmed cell death.
Mai1 Protein Acts Between Host Recognition of Pathogen Effectors and Mitogen-Activated Protein Kinase Signaling · 2019
Opposite direction
positive
CSEP0139 expression suppressed BAX- and Nt MEK2 DD-triggered cell death in N. benthamiana but not AVR a13 /MLA13-triggered death.
The barley powdery mildew effectors CSEP0139 and CSEP0182 suppress cell death and promote B. graminis fungal virulence in plants · 2021
Opposite direction

33 papers more in this group

See all 42 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.

Other papers on the same question

transgenic · cytology · Nicotiana benthamianaPositive and negative results