Claim · model-written summary
Phenotypic and transcriptomic analyses of MdDAM1 and MdDAM4 overexpression or silencing lines confirmed both genes as essential for dormancy regulation.
- Taxon
- apple
Malus domesticat0 - Gene
- MdDAM1 and MdDAM4e1
- Outcome
- dormancy regulatione0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
t0“apple”
e0“Phenotypic and transcriptomic analyses confirmed that both genes are essential for dormancy regulation”
e1“apple trees were genetically modified to overexpress or silence MdDAM1 and MdDAM4”
Title
Functional characterization of Dormancy-Associated MADS-Box genes in apple
J. Lempe; S. Schröpfer; L. Baader; et al. Acta Horticulturae 2026. doi:10.17660/actahortic.2026.1454.33
Other claims from this paper (5)
- Observation Several DAM genes were identified on different chromosomes of the apple genome sequence.
- Observation Apple trees lacking functional MdDAM1 or MdDAM4 failed to enter dormancy.
- Observation Of 732 regenerated shoot lines from CRISPR/Cas editing of MdDAM1, 60 showed mutations.
- Observation None of the mutated lines had both alleles of MdDAM1 mutated.
- Observation A second regeneration step yielded 17 lines with uniform biallelic MdDAM1 mutations.