Intervention effectmodel-written summary

TF suppressed phosphorylated NF-κB p65 and IκBα expression in rats with chronic prostatitis.

A claim from Extraction optimization and constituent analysis of total flavonoid from Hosta plantaginea (Lam.) Aschers flowers and its ameliorative effect on chronic prostatitis via inhibition of multiple inflammatory pathways in rats · 2023

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

TF suppressed phosphorylated NF-κB p65 and IκBα expression in rats with chronic prostatitis.

Taxon
Hosta plantagineaHosta plantagineae0
Treatment
TF (25 and 100 mg/kg, p.o.)e3
Gene
nuclear factor kappa-B (NF-κB) p65e7
Outcome
phosphorylated protein expressionse7
Direction
suppressede7
Qualifier
inhibitor of NF-κB alpha (IκBα)e7

Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValue

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Hosta plantaginea
Hosta plantaginea · TaxonStan Shebs · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Hosta plantaginea (Lam.) Aschers flowers (HPF) are well-known for their high flavonoid content”

✓ located verbatim in the source · abstract, characters 31–125
e3

“Efficacy of TF (25 and 100 mg/kg, p.o.) on CP was evaluated in prostate antigen emulsion-induced autoimmune CP rat model”

✓ located verbatim in the source · abstract, characters 775–895
e7

“suppressed phosphorylated protein expressions of nuclear factor kappa-B (NF-κB) p65, inhibitor of NF-κB alpha (IκBα), c-Jun N-terminal kinase (JNK), p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase (Erk)”

✓ located verbatim in the source · abstract, characters 1771–2008

Title

Extraction optimization and constituent analysis of total flavonoid from Hosta plantaginea (Lam.) Aschers flowers and its ameliorative effect on chronic prostatitis via inhibition of multiple inflammatory pathways in rats

Li Yang; Fengxiang Zhang; Weiwei He; et al. Journal of Ethnopharmacology 2023. doi:10.1016/j.jep.2023.116922

Other claims from this paper (11)

Record rev-e26bc0f038a4f6616ec08b8553fcd7c966955fea9e1a059e53c4369e28f6d779 · schema claims-v0.9 · position 6 in the model’s answer