Claim · model-written summary
Two novel triterpene glycosides were isolated from Hedera rhombea leaves.
- Taxon
- Hedera rhombea
Hedera rhombeae0
- Organ / stage
- leavese0
- Outcome
- Two novel triterpene glycosides (1 and 2)e0
Verbatim
e0“Two novel triterpene glycosides (1 and 2), 17 known triterpene glycosides (3–19), two known flavonoid glycosides (20 and 21), and two known norsesquiterpene glucosides (22 and 23) were isolated from Hedera rhombea (Araliaceae) leaves.”
Title
Chemical Components in Hedera rhombea Leaves and Their Cytotoxicity
Akihito Yokosuka; Tatsuya Shimomura; Shohei Yokogawa; et al. Chemical and Pharmaceutical Bulletin 2022. doi:10.1248/cpb.c21-00907
Other claims from this paper (8)
- Observation Seventeen known triterpene glycosides were isolated from Hedera rhombea leaves.
- Observation Two known flavonoid glycosides were isolated from Hedera rhombea leaves.
- Observation Two known norsesquiterpene glucosides were isolated from Hedera rhombea leaves.
- Observation The structures of compounds 1 and 2 were determined.
- Observation Compound 9 was cytotoxic to HL-60 cells, with an IC50 of 7.2 µM.
- Observation Compound 10 was cytotoxic to HL-60 cells, with an IC50 of 21.9 µM.
- Observation Compound 11 was cytotoxic to HL-60 cells, with an IC50 of 32.8 µM.
- Observation Other isolated compounds were not cytotoxic at 50 μM.