Abstract
The herbicide glyphosate inhibits the shikimate pathway of the synthesis of amino acids such as phenylalanine, tyrosine, and tryptophan. However, much uncertainty remains concerning precisely how glyphosate kills plants or affects cellular redox homeostasis and related processes in glyphosate-sensitive and glyphosate-resistant crop plants. To address this issue, we performed an integrated study of photosynthesis, leaf proteomes, amino acid profiles, and redox profiles in the glyphosate-sensitive soybean (Glycine max) genotype PAN809 and glyphosate-resistant Roundup Ready Soybean (RRS). RRS leaves accumulated much more glyphosate than the sensitive line but showed relatively few changes in amino acid metabolism. Photosynthesis was unaffected by glyphosate in RRS leaves, but decreased abundance of photosynthesis/photorespiratory pathway proteins was observed together with oxidation of major redox pools. While treatment of a sensitive genotype with glyphosate rapidly inhibited photosynthesis and triggered the appearance of a nitrogen-rich amino acid profile, there was no evidence of oxidation of the redox pools. There was, however, an increase in starvation-associated and defense proteins. We conclude that glyphosate-dependent inhibition of soybean leaf metabolism leads to the induction of defense proteins without sustained oxidation. Conversely, the accumulation of high levels of glyphosate in RRS enhances cellular oxidation, possibly through mechanisms involving stimulation of the photorespiratory pathway.
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Claims 10
Claim · model-written summary
RRS leaves accumulated much more glyphosate than the sensitive line.
- Taxon
- soybean
Glycine maxe0 - Material
- RRSe1
- Outcome
- accumulated much more glyphosatee1
- Direction
- much moree1
- Comparator
- the sensitive linee1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“we performed an integrated study of photosynthesis, leaf proteomes, amino acid profiles, and redox profiles in the glyphosate-sensitive soybean (Glycine max) genotype PAN809 and glyphosate-resistant Roundup Ready Soybean (RRS)”
e1“RRS leaves accumulated much more glyphosate than the sensitive line but showed relatively few changes in amino acid metabolism”
Claim · model-written summary
RRS showed relatively few changes in amino acid metabolism.
- Taxon
- soybeanGlycine maxe0
- Material
- RRSe1
- Outcome
- changes in amino acid metabolisme1
- Qualifier
- relatively fewe1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“we performed an integrated study of photosynthesis, leaf proteomes, amino acid profiles, and redox profiles in the glyphosate-sensitive soybean (Glycine max) genotype PAN809 and glyphosate-resistant Roundup Ready Soybean (RRS)”
e1“RRS leaves accumulated much more glyphosate than the sensitive line but showed relatively few changes in amino acid metabolism”
Claim · model-written summary
Photosynthesis was unaffected by glyphosate in RRS leaves.
- Taxon
- soybeanGlycine maxe0
- Material
- RRSe2
- Treatment
- glyphosatee2
- Outcome
- Photosynthesise2
- Direction
- unaffectede2
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“we performed an integrated study of photosynthesis, leaf proteomes, amino acid profiles, and redox profiles in the glyphosate-sensitive soybean (Glycine max) genotype PAN809 and glyphosate-resistant Roundup Ready Soybean (RRS)”
e2“Photosynthesis was unaffected by glyphosate in RRS leaves, but decreased abundance of photosynthesis/photorespiratory pathway proteins was observed together with oxidation of major redox pools”
Claim · model-written summary
Abundance of photosynthesis and photorespiratory pathway proteins decreased in RRS leaves.
- Taxon
- soybeanGlycine maxe0
- Material
- RRSe2
- Outcome
- abundance of photosynthesis/photorespiratory pathway proteinse2
- Direction
- decreasede2
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“we performed an integrated study of photosynthesis, leaf proteomes, amino acid profiles, and redox profiles in the glyphosate-sensitive soybean (Glycine max) genotype PAN809 and glyphosate-resistant Roundup Ready Soybean (RRS)”
e2“Photosynthesis was unaffected by glyphosate in RRS leaves, but decreased abundance of photosynthesis/photorespiratory pathway proteins was observed together with oxidation of major redox pools”
Claim · model-written summary
Major redox pools were oxidized in RRS leaves.
- Taxon
- soybeanGlycine maxe0
- Material
- RRSe2
- Outcome
- oxidation of major redox poolse2
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“we performed an integrated study of photosynthesis, leaf proteomes, amino acid profiles, and redox profiles in the glyphosate-sensitive soybean (Glycine max) genotype PAN809 and glyphosate-resistant Roundup Ready Soybean (RRS)”
e2“Photosynthesis was unaffected by glyphosate in RRS leaves, but decreased abundance of photosynthesis/photorespiratory pathway proteins was observed together with oxidation of major redox pools”
Claim · model-written summary
Glyphosate treatment of the sensitive genotype rapidly inhibited photosynthesis.
- Taxon
- soybeanGlycine maxe0
- Material
- sensitive genotypee3
- Treatment
- glyphosatee3
- Outcome
- photosynthesise3
- Direction
- inhibitede3
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“we performed an integrated study of photosynthesis, leaf proteomes, amino acid profiles, and redox profiles in the glyphosate-sensitive soybean (Glycine max) genotype PAN809 and glyphosate-resistant Roundup Ready Soybean (RRS)”
e3“While treatment of a sensitive genotype with glyphosate rapidly inhibited photosynthesis and triggered the appearance of a nitrogen-rich amino acid profile, there was no evidence of oxidation of the redox pools”
Claim · model-written summary
Glyphosate treatment of the sensitive genotype triggered a nitrogen-rich amino acid profile.
- Taxon
- soybeanGlycine maxe0
- Material
- sensitive genotypee3
- Outcome
- nitrogen-rich amino acid profilee3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“we performed an integrated study of photosynthesis, leaf proteomes, amino acid profiles, and redox profiles in the glyphosate-sensitive soybean (Glycine max) genotype PAN809 and glyphosate-resistant Roundup Ready Soybean (RRS)”
e3“While treatment of a sensitive genotype with glyphosate rapidly inhibited photosynthesis and triggered the appearance of a nitrogen-rich amino acid profile, there was no evidence of oxidation of the redox pools”
Claim · model-written summary
The sensitive genotype showed no evidence of oxidation of the redox pools after glyphosate treatment.
- Taxon
- soybeanGlycine maxe0
- Material
- sensitive genotypee3
- Outcome
- oxidation of the redox poolse3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“we performed an integrated study of photosynthesis, leaf proteomes, amino acid profiles, and redox profiles in the glyphosate-sensitive soybean (Glycine max) genotype PAN809 and glyphosate-resistant Roundup Ready Soybean (RRS)”
e3“While treatment of a sensitive genotype with glyphosate rapidly inhibited photosynthesis and triggered the appearance of a nitrogen-rich amino acid profile, there was no evidence of oxidation of the redox pools”
Claim · model-written summary
Glyphosate increased starvation-associated and defense proteins in the sensitive genotype.
- Taxon
- soybeanGlycine maxe0
- Material
- sensitive genotypee3
- Treatment
- glyphosatee3
- Outcome
- starvation-associated and defense proteinse4
- Direction
- increasee4
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“we performed an integrated study of photosynthesis, leaf proteomes, amino acid profiles, and redox profiles in the glyphosate-sensitive soybean (Glycine max) genotype PAN809 and glyphosate-resistant Roundup Ready Soybean (RRS)”
e3“While treatment of a sensitive genotype with glyphosate rapidly inhibited photosynthesis and triggered the appearance of a nitrogen-rich amino acid profile, there was no evidence of oxidation of the redox pools”
e4“There was, however, an increase in starvation-associated and defense proteins”
Claim · model-written summary
High accumulation of glyphosate in RRS enhances cellular oxidation, possibly through stimulation of the photorespiratory pathway.
- Taxon
- soybeanGlycine maxe0
- Material
- RRSe5
- Treatment
- accumulation of high levels of glyphosatee5
- Outcome
- cellular oxidatione5
- Direction
- enhancese5
- Qualifier
- possibly through mechanisms involving stimulation of the photorespiratory pathwaye5
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“we performed an integrated study of photosynthesis, leaf proteomes, amino acid profiles, and redox profiles in the glyphosate-sensitive soybean (Glycine max) genotype PAN809 and glyphosate-resistant Roundup Ready Soybean (RRS)”
e5“Conversely, the accumulation of high levels of glyphosate in RRS enhances cellular oxidation, possibly through mechanisms involving stimulation of the photorespiratory pathway”
The same questions in other papers
glyphosate · disease · Glycine max (soybean)Positive and negative results
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See all 25 papers →glyphosate · physiology: photosynthesis · Glycine max (soybean)Results agree
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See all 9 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.