Abstract
Excessive accumulation of nickel (Ni) can be toxic to plants. In Arabidopsis thaliana, the Fe²⁺ transporter, iron (Fe)-regulated transporter1 (IRT1), mediates Fe uptake and also implicates in Ni²⁺ uptake at roots; however, the underlying mechanism of Ni²⁺ uptake and accumulation remains unelucidated. In the present study, we found that zinc (Zn) deficient conditions resulted in increased accumulation of Ni in plants, particularly in roots, in A. thaliana. In order to elucidate the underlying mechanisms of Ni uptake correlating zinc condition, we traced 63Ni isotope in response to Zn and found that (i) Zn deficiency induces short-term Ni²⁺ absorption and (ii) Zn²⁺ inhibits Ni²⁺ uptake, suggesting competitive uptake between Ni and Zn. Furthermore, the Zrt/Irt-like protein 3 (ZIP3)-defective mutant with an elevated Zn-deficient response exhibited higher Ni accumulation than the wild type, further supporting that the response to Zn deficiency induces Ni accumulation. Previously, expression profile study demonstrated that IRT1 expression is not inducible by Zn deficiency. In the present study, we found increased Ni accumulation in IRT1-null mutant under Zn deficiency in agar culture. These suggest that Zn deficiency induces Ni accumulation in an IRT1-independen manner. The present study revealed that Ni accumulation is inducible in response to Zn deficiency, which may be attributable to a Zn uptake transporter induced by Zn deficiency.
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Claims 7
Claim · model-written summary
Zinc deficiency increased nickel accumulation, especially in roots.
- Taxon
- A. thaliana
Arabidopsis thalianae0 - Organ / stage
- rootse0
- Treatment
- zinc (Zn) deficient conditionse0
- Outcome
- accumulation of Nie0
- Direction
- increasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“zinc (Zn) deficient conditions resulted in increased accumulation of Ni in plants, particularly in roots, in A. thaliana.”
Claim · model-written summary
Zinc deficiency induced short-term Ni²⁺ absorption.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Treatment
- Zn deficiencye0
- Outcome
- short-term Ni²⁺ absorptione0
- Direction
- inducese0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Zn deficiency induces short-term Ni²⁺ absorption”
t0“Arabidopsis thaliana”
Claim · model-written summary
Zn²⁺ inhibited Ni²⁺ uptake.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Treatment
- Zn²⁺e0
- Outcome
- Ni²⁺ uptakee0
- Direction
- inhibitse0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Zn²⁺ inhibits Ni²⁺ uptake”
t0“Arabidopsis thaliana”
Claim · model-written summary
The ZIP3-defective mutant accumulated more nickel than wild type.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Material
- Zrt/Irt-like protein 3 (ZIP3)-defective mutante0
- Gene
- Zrt/Irt-like protein 3 (ZIP3)e0
- Outcome
- Ni accumulatione0
- Direction
- highere0
- Comparator
- wild typee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the Zrt/Irt-like protein 3 (ZIP3)-defective mutant with an elevated Zn-deficient response exhibited higher Ni accumulation than the wild type”
t0“Arabidopsis thaliana”
Claim · model-written summary
An IRT1-null mutant accumulated more nickel under zinc deficiency in agar culture.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Material
- IRT1-null mutante0
- Treatment
- Zn deficiencye0
- Gene
- IRT1e0
- Outcome
- Ni accumulatione0
- Direction
- increasede0
- Setting
- agar culturee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“increased Ni accumulation in IRT1-null mutant under Zn deficiency in agar culture”
t0“Arabidopsis thaliana”
Claim · model-written summary
The authors inferred that zinc deficiency induces nickel accumulation independently of IRT1.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Treatment
- Zn deficiencye0
- Gene
- IRT1e0
- Outcome
- Ni accumulatione0
- Direction
- inducese0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Zn deficiency induces Ni accumulation in an IRT1-independen manner”
t0“Arabidopsis thaliana”
Claim · model-written summary
The authors proposed that a zinc uptake transporter induced by deficiency may underlie nickel accumulation.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Treatment
- Zn deficiencye0
- Outcome
- Ni accumulatione0
- Qualifier
- Zn uptake transporter induced by Zn deficiencye0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Ni accumulation is inducible in response to Zn deficiency, which may be attributable to a Zn uptake transporter induced by Zn deficiency”
t0“Arabidopsis thaliana”
The same questions in other papers
zinc atom · nutrient: content · Arabidopsis thaliana (thale cress)Positive and negative results
1 paper in the same direction as this paper · 1 in the opposite direction
This paper is about lacking the nutrient, so it counts the other way round here.
- negative
- positive
Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.