Abstract
Mimusops elengi is a small or large evergreen tree (Sapotaceae) of western peninsula and is found in south India. It has been in use in the indigenous system of medicine since antiquity as a specific cure for the diseases of gum and teeth. The drug has been reported to be bitter, astringent, tonic, febrifuge, and as a cure for dysentery and constipation. The cytotoxic effects of ethanolic extract of barks of M. elengi was investigated on meristimatic cells of root tips of Allium cepa. The experiment was carried out by using different concentrations (2.5, 5, 10 mg/mL) of standard cytotoxic drug cyclophosphamide and ethanolic extract. After 48 h and 96 h root length and mitotic index were calculated. The photomicrographs had shown the chromosomal abnormalities, stickiness, etc. with increasing concentration of ethanolic extract. The results of the presented study revealed that there is a significant decrease in percent mitotic index and root length of A. cepa with respective time and with increasing concentration.
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Claims 2
Claim · model-written summary
Ethanolic extract of M. elengi bark significantly decreased percent mitotic index and root length of Allium cepa with time and increasing concentration.
- Taxon
- Allium cepa
Allium cepae1 - Organ / stage
- root tipse1
- Treatment
- ethanolic extract of barks of M. elengie1
- Outcome
- percent mitotic index and root lengthe2
- Direction
- decreasee2
- Qualifier
- with respective time and with increasing concentratione2
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“The cytotoxic effects of ethanolic extract of barks of M. elengi was investigated on meristimatic cells of root tips of Allium cepa”
e2“The results of the presented study revealed that there is a significant decrease in percent mitotic index and root length of A. cepa with respective time and with increasing concentration”
Claim · model-written summary
Photomicrographs showed chromosomal abnormalities and stickiness in Allium cepa cells with increasing ethanolic extract concentration.
- Taxon
- Allium cepaAllium cepae1
- Treatment
- ethanolic extracte3
- Outcome
- chromosomal abnormalities, stickinesse3
- Qualifier
- with increasing concentratione3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“The cytotoxic effects of ethanolic extract of barks of M. elengi was investigated on meristimatic cells of root tips of Allium cepa”
e3“The photomicrographs had shown the chromosomal abnormalities, stickiness, etc. with increasing concentration of ethanolic extract”
The same questions in other papers
botanical · cytology · Allium cepa (onion)Positive and negative results
25 papers in the same direction as this paper · 89 in the opposite direction · 1 reporting no difference from an alternative
- negative
- negative
- negative
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See all 116 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.