Abstract
Plants possess inducible systemic defense responses when locally infected by pathogens. Bacterial infection results in the increased accumulation of the mobile metabolite azelaic acid, a nine-carbon dicarboxylic acid, in the vascular sap of Arabidopsis that confers local and systemic resistance against the pathogen Pseudomonas syringae. Azelaic acid primes plants to accumulate salicylic acid (SA), a known defense signal, upon infection. Mutation of the AZELAIC ACID INDUCED 1 (AZI1) gene, which is induced by azelaic acid, results in the specific loss of systemic immunity triggered by pathogen or azelaic acid and of the priming of SA induction in plants. Furthermore, the predicted secreted protein AZI1 is also important for generating vascular sap that confers disease resistance. Thus, azelaic acid and AZI1 are components of plant systemic immunity involved in priming defenses.
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Claims 6
Claim · model-written summary
Bacterial infection increased azelaic acid in Arabidopsis vascular sap.
- Taxon
- Arabidopsis
Arabidopsise0 - Organ / stage
- vascular sape0
- Treatment
- Bacterial infectione0
- Outcome
- accumulation of the mobile metabolite azelaic acide0
- Direction
- increasede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Bacterial infection results in the increased accumulation of the mobile metabolite azelaic acid, a nine-carbon dicarboxylic acid, in the vascular sap of Arabidopsis”
Claim · model-written summary
Azelaic acid conferred local and systemic resistance against Pseudomonas syringae.
- Taxon
- ArabidopsisArabidopsise0
- Treatment
- azelaic acide0
- Interactor
- Pseudomonas syringae
Pseudomonas syringaee0pathogen - Outcome
- local and systemic resistancee0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“azelaic acid, a nine-carbon dicarboxylic acid, in the vascular sap of Arabidopsis that confers local and systemic resistance against the pathogen Pseudomonas syringae”
Claim · model-written summary
Azelaic acid primed salicylic acid accumulation upon infection.
- Taxon
- ArabidopsisArabidopsise1
- Treatment
- Azelaic acide0
- Outcome
- accumulate salicylic acide0
- Qualifier
- upon infectione0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Azelaic acid primes plants to accumulate salicylic acid (SA), a known defense signal, upon infection”
t0“Plant Immunity”
e1“Bacterial infection results in the increased accumulation of the mobile metabolite azelaic acid, a nine-carbon dicarboxylic acid, in the vascular sap of Arabidopsis”
Claim · model-written summary
AZI1 mutation caused loss of pathogen- or azelaic acid-triggered systemic immunity.
- Taxon
- plantsViridiplantaee0
- Treatment
- Mutatione0
- Gene
- AZELAIC ACID INDUCED 1 (AZI1)e0
- Outcome
- systemic immunitye0
- Direction
- losse0
Not reportedComparator
Verbatim
e0“Mutation of the AZELAIC ACID INDUCED 1 (AZI1) gene, which is induced by azelaic acid, results in the specific loss of systemic immunity triggered by pathogen or azelaic acid and of the priming of SA induction in plants”
t0“Plant Immunity”
Claim · model-written summary
AZI1 mutation caused loss of primed salicylic acid induction.
- Taxon
- plantsViridiplantaee0
- Treatment
- Mutatione0
- Gene
- AZELAIC ACID INDUCED 1 (AZI1)e0
- Outcome
- priming of SA inductione0
- Direction
- losse0
Not reportedComparator
Verbatim
e0“Mutation of the AZELAIC ACID INDUCED 1 (AZI1) gene, which is induced by azelaic acid, results in the specific loss of systemic immunity triggered by pathogen or azelaic acid and of the priming of SA induction in plants”
t0“Plant Immunity”
Claim · model-written summary
AZI1 mutation altered the generation of resistance-conferring vascular sap.
- Taxon
- plantsViridiplantaee1
- Gene
- AZI1e0
- Outcome
- vascular sap that confers disease resistancee0
Not reportedTreatmentComparatorDirection
Verbatim
e0“the predicted secreted protein AZI1 is also important for generating vascular sap that confers disease resistance”
t0“Plant Immunity”
e1“Azelaic acid primes plants to accumulate salicylic acid (SA), a known defense signal, upon infection”
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