Abstract
Tridiphane [2-(3,5-dichlorophenyl)-2-(2,2,2-trichloroethyl)oxirane] inhibited growth of seedling corn ( Zea mays L. ‘DK T 1100’), wheat ( Triticum aesetivum L. ‘Arthur’), and sorghum ( Sorghum vulgare Pers. ‘DK 42Y’) in growth chamber experiments. These inhibitions were partially circumvented by simultaneous treatment with OTC ( L -2-oxothiazolidine-4-carboxylic acid). Tridiphane, atrazine [6-chloro- N -ethyl- N′ -(1-methylethyl)-1,3,5-triazine-2,4-diamine], and OTC each increased levels of low molecular weight thiols (glutathione) in intact roots of treated corn seedlings, but only OTC did in excised roots. Tridiphane and atrazine caused a decrease in thiol content of excised roots. Tridiphane treatments reduced the amount of glutathione S -transferase activity extractable from corn roots, and this reduction was circumvented partially by OTC applied in combination with tridiphane. These data present evidence that tridiphane interference with cysteine or glutathione metabolism can be reversed by increasing cellular content of cysteine.
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The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.
Claims 11
Claim · model-written summary
Tridiphane inhibited growth of seedling corn.
- Taxon
- corn
Zea mays subsp. mayse0 - Material
- DK T 1100e0
- Treatment
- Tridiphanee0
- Outcome
- growthe0
- Direction
- inhibitede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Tridiphane [2-(3,5-dichlorophenyl)-2-(2,2,2-trichloroethyl)oxirane] inhibited growth of seedling corn ( Zea mays L. ‘DK T 1100’)”
Claim · model-written summary
Tridiphane inhibited growth of seedling wheat.
- Taxon
- wheat
Triticum aestivume0 - Material
- Arthure0
- Treatment
- Tridiphanee0
- Outcome
- growthe0
- Direction
- inhibitede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Tridiphane [2-(3,5-dichlorophenyl)-2-(2,2,2-trichloroethyl)oxirane] inhibited growth of seedling corn ( Zea mays L. ‘DK T 1100’), wheat ( Triticum aesetivum L. ‘Arthur’), and sorghum ( Sorghum vulgare Pers. ‘DK 42Y’)”
Claim · model-written summary
Tridiphane inhibited growth of seedling sorghum.
SorghumNot reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Tridiphane [2-(3,5-dichlorophenyl)-2-(2,2,2-trichloroethyl)oxirane] inhibited growth of seedling corn ( Zea mays L. ‘DK T 1100’), wheat ( Triticum aesetivum L. ‘Arthur’), and sorghum ( Sorghum vulgare Pers. ‘DK 42Y’)”
Claim · model-written summary
Simultaneous OTC treatment partially circumvented tridiphane growth inhibition in corn, wheat and sorghum.
- Taxon
- cornZea mays subsp. mayse1
- Treatment
- simultaneous treatment with OTCe0
- Outcome
- inhibitionse0
- Direction
- partially circumventede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“These inhibitions were partially circumvented by simultaneous treatment with OTC ( L -2-oxothiazolidine-4-carboxylic acid).”
e1“seedling corn ( Zea mays L. ‘DK T 1100’), wheat ( Triticum aesetivum L. ‘Arthur’), and sorghum ( Sorghum vulgare Pers. ‘DK 42Y’)”
Claim · model-written summary
Tridiphane, atrazine and OTC each increased low molecular weight thiols in intact corn seedling roots.
- Taxon
- cornZea mays subsp. mayse0
- Organ / stage
- intact rootse0
- Treatment
- Tridiphanee0
- Compound
- glutathionee0
- Outcome
- low molecular weight thiolse0
- Direction
- increasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Tridiphane, atrazine [6-chloro- N -ethyl- N′ -(1-methylethyl)-1,3,5-triazine-2,4-diamine], and OTC each increased levels of low molecular weight thiols (glutathione) in intact roots of treated corn seedlings”
Claim · model-written summary
Only OTC increased thiols in excised corn roots.
- Taxon
- cornZea mays subsp. mayse0
- Organ / stage
- excised rootse0
- Treatment
- OTCe0
- Outcome
- low molecular weight thiolse0
- Direction
- increasede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“and OTC each increased levels of low molecular weight thiols (glutathione) in intact roots of treated corn seedlings, but only OTC did in excised roots.”
Claim · model-written summary
Tridiphane decreased thiol content in excised corn roots.
- Taxon
- cornZea mays subsp. mayse1
- Organ / stage
- excised rootse0
- Treatment
- Tridiphanee0
- Outcome
- thiol contente0
- Direction
- decreasee0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Tridiphane and atrazine caused a decrease in thiol content of excised roots.”
e1“corn seedlings”
Claim · model-written summary
Atrazine decreased thiol content in excised corn roots.
- Taxon
- cornZea mays subsp. mayse1
- Organ / stage
- excised rootse0
- Treatment
- atrazinee0
- Outcome
- thiol contente0
- Direction
- decreasee0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Tridiphane and atrazine caused a decrease in thiol content of excised roots.”
e1“corn seedlings”
Claim · model-written summary
Tridiphane reduced extractable glutathione S-transferase activity in corn roots.
- Taxon
- cornZea mays subsp. mayse0
- Organ / stage
- rootse0
- Treatment
- Tridiphane treatmentse0
- Outcome
- glutathione S -transferase activitye0
- Direction
- reducede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Tridiphane treatments reduced the amount of glutathione S -transferase activity extractable from corn roots”
Claim · model-written summary
OTC partially circumvented tridiphane-induced reduction of glutathione S-transferase activity in corn roots.
- Taxon
- cornZea mays subsp. mayse0
- Organ / stage
- rootse0
- Treatment
- OTC applied in combination with tridiphanee0
- Outcome
- glutathione S -transferase activitye0
- Direction
- circumvented partiallye0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Tridiphane treatments reduced the amount of glutathione S -transferase activity extractable from corn roots, and this reduction was circumvented partially by OTC applied in combination with tridiphane.”
Claim · model-written summary
The authors infer that increasing cellular cysteine can reverse tridiphane interference with cysteine or glutathione metabolism.
- Taxon
- cornZea mays subsp. mayse1
- Treatment
- increasing cellular content of cysteinee0
- Compound
- cysteinee0
- Outcome
- cysteine or glutathione metabolisme0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“tridiphane interference with cysteine or glutathione metabolism can be reversed by increasing cellular content of cysteine.”
e1“corn roots”
The same questions in other papers
Tridiphane · molecular: metabolites · Zea mays (maize)Positive and negative results
1 in the opposite direction
- negative
Tridiphane · growth · Zea mays (maize)Positive and negative results
1 paper in the same direction as this paper · 1 in the opposite direction
- positive
- negative
atrazine · molecular: metabolites · Zea mays (maize)Positive and negative results
1 paper in the same direction as this paper · 5 in the opposite direction
- positive
- positive
- positive
3 papers more in this group
See all 7 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.