Abstract
Ultraviolet-B (UV–B) radiation profoundly affects plant photomorphogenesis and secondary metabolism, yet its regulatory role in lettuce ( Lactuca sativa ) remains poorly understood. We conducted metabolome and transcriptome analyses to reveal the molecular basis of UV–B adaptation in highland-grown lettuce. Flavonoid accumulation was enhanced as a key adaptive strategy for UV–B acclimation. The key UV–B signaling components LsHY5a / b showed positive correlations with ten LsBBXs and flavonoid/anthocyanin-related genes. UV–B treatment rapidly induced the transcription of LsHY5a / b and LsBBX22-1 . LsBBX22-1 physically interacted with LsHY5a/b. While LsBBX22-1 activated the expression of anthocyanin-related genes, it could not bind directly to their promoters. By contrast, LsHY5a/b directly bound to the promoters of LsCHS1, LsCHI3, and LsF3H . Thus, LsBBX22 and LsHY5a/b acted synergistically to regulate UV–B-induced anthocyanin biosynthesis. This study clarified the molecular mechanism of the LsBBX22-1–LsHY5a/b module in promoting UV–B-induced anthocyanin accumulation in lettuce, providing a theoretical basis for cultivating high-quality vegetables in highland regions.
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Claims 9
Claim · model-written summary
UV–B enhanced flavonoid accumulation.
- Taxon
- lettuce
Lactuca sativat0 - Outcome
- Flavonoid accumulatione0
- Direction
- enhancede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Flavonoid accumulation was enhanced as a key adaptive strategy for UV–B acclimation”
t0“Lettuce”
Claim · model-written summary
LsHY5a/b correlated positively with ten LsBBXs and flavonoid genes.
- Taxon
- lettuceLactuca sativat0
- Gene
- LsHY5a / be0
- Outcome
- positive correlationse0
- Direction
- positivee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“LsHY5a / b showed positive correlations with ten LsBBXs and flavonoid/anthocyanin-related genes”
t0“Lettuce”
Claim · model-written summary
UV–B rapidly induced LsHY5a/b transcription.
- Taxon
- lettuceLactuca sativat0
- Gene
- LsHY5a / be0
- Outcome
- transcription of LsHY5a / be0
- Direction
- inducede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“UV–B treatment rapidly induced the transcription of LsHY5a / b and LsBBX22-1”
t0“Lettuce”
Claim · model-written summary
UV–B rapidly induced LsBBX22-1 transcription.
- Taxon
- lettuceLactuca sativat0
- Gene
- LsBBX22-1e0
- Outcome
- transcriptione0
- Direction
- inducede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“UV–B treatment rapidly induced the transcription of LsHY5a / b and LsBBX22-1”
t0“Lettuce”
Claim · model-written summary
LsBBX22-1 physically interacted with LsHY5a/b.
- Taxon
- lettuceLactuca sativat0
- Gene
- LsBBX22-1e0
- Outcome
- physically interacted with LsHY5a/be0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“LsBBX22-1 physically interacted with LsHY5a/b”
t0“Lettuce”
Claim · model-written summary
LsBBX22-1 activated anthocyanin-related gene expression.
- Taxon
- lettuceLactuca sativat0
- Gene
- LsBBX22-1e0
- Outcome
- expression of anthocyanin-related genese0
- Direction
- activatede0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“LsBBX22-1 activated the expression of anthocyanin-related genes”
t0“Lettuce”
Claim · model-written summary
LsBBX22-1 did not bind directly to anthocyanin-related gene promoters.
- Taxon
- lettuceLactuca sativat0
- Outcome
- could not bind directly to their promoterse0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“it could not bind directly to their promoters”
t0“Lettuce”
Claim · model-written summary
LsHY5a/b bound directly to the LsCHS1, LsCHI3 and LsF3H promoters.
- Taxon
- lettuceLactuca sativat0
- Gene
- LsHY5a/be0
- Outcome
- directly bound to the promoterse0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“LsHY5a/b directly bound to the promoters of LsCHS1, LsCHI3, and LsF3H”
t0“Lettuce”
Claim · model-written summary
LsBBX22 and LsHY5a/b acted synergistically in UV–B induced anthocyanin biosynthesis.
- Taxon
- lettuceLactuca sativat0
- Gene
- LsBBX22 and LsHY5a/be0
- Outcome
- UV–B-induced anthocyanin biosynthesise0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“LsBBX22 and LsHY5a/b acted synergistically to regulate UV–B-induced anthocyanin biosynthesis”
t0“Lettuce”