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Mechanismobservedoriginal resultmeasured

Claim · model-written summary

Only one neocentromere activating region is sufficient to move many knobs.

Taxon
MaizeZea mayst0
Outcome
move many knobse0
Qualifier
one of the neocentromere-activating regionse0

Verbatim

t0

“Maize”

✓ located verbatim in the source · title, characters 67–72
e0

“only one of the neocentromere-activating regions is sufficient to move many knobs”

✓ located verbatim in the source · abstract, characters 642–723

Title

Four Loci on Abnormal Chromosome 10 Contribute to Meiotic Drive in Maize

Evelyn N Hiatt; R Kelly Dawe Genetics 2003. doi:10.1093/genetics/164.2.699

Other claims from this paper (6)
Mechanismauthor interpretationoriginal resultmeasured

Claim · model-written summary

Maize knobs may be considered megatransposable elements.

Taxon
maizeZea mayst0
Outcome
maize knob may be consider as megatransposable elementse0
Qualifier
knob polymorphism and complex structuree0

Verbatim

e0

“knob polymorphism and complex structure suggest that maize knob may be consider as megatransposable elements”

✓ located verbatim in the source · abstract, characters 1773–1881
t0

“maize”

✓ located verbatim in the source · title, characters 54–59

Title

Complex structure of knobs and centromeric regions in maize chromosomes.

E V Ananiev; R L Phillips; H W Rines PubMed 2000

Other claims from this paper (13)
Mechanismauthor interpretationoriginal resultnegativemeasured

Claim · model-written summary

The authors interpret increased stickiness as involving both knob and nonknob chromosome regions.

Taxon
maizeZea mayst0
Outcome
chromosomal stickinesse0
Direction
increasee0
Qualifier
stickiness of knob and nonknob chromosomal regionse0

Verbatim

e0

“Thus, the increase in chromosomal stickiness appears to be due to an increase in stickiness of knob and nonknob chromosomal regions”

✓ located verbatim in the source · abstract, characters 966–1097
t0

“PRINS-Labeled Knobs Are Not Associated with Increased Chromosomal Stickiness in the Maize st1 Mutant”

✓ located verbatim in the source · title, characters 0–100

Title

PRINS-Labeled Knobs Are Not Associated with Increased Chromosomal Stickiness in the Maize st1 Mutant

T. C. Tatum Journal of Heredity 2006. doi:10.1093/jhered/esl014

Other claims from this paper (6)
Mechanismauthor interpretationoriginal resultmeasured

Claim · model-written summary

Transposition may influence knob evolution.

Taxon
maizeZea mayst0
Outcome
evolution of knobse0
Qualifier
transpositione0

Not reportedDirection

Verbatim

e0

“environmental factors and transposition may play a role in the evolution of knobs.”

✓ located verbatim in the source · abstract, characters 1122–1204
t0

“Maize”

✓ located verbatim in the source · title, characters 48–53

Title

Meiotic Drive of Chromosomal Knobs Reshaped the Maize Genome

Edward S Buckler; Tara L Phelps-Durr; Carlyn S Keith Buckler; et al. Genetics 1999. doi:10.1093/genetics/153.1.415

Other claims from this paper (6)
Mechanismauthor interpretationoriginal resultmeasured

Claim · model-written summary

Environmental factors may influence knob evolution.

Taxon
maizeZea mayst0
Outcome
evolution of knobse0
Qualifier
environmental factorse0

Not reportedDirection

Verbatim

e0

“environmental factors and transposition may play a role in the evolution of knobs.”

✓ located verbatim in the source · abstract, characters 1122–1204
t0

“Maize”

✓ located verbatim in the source · title, characters 48–53

Title

Meiotic Drive of Chromosomal Knobs Reshaped the Maize Genome

Edward S Buckler; Tara L Phelps-Durr; Carlyn S Keith Buckler; et al. Genetics 1999. doi:10.1093/genetics/153.1.415

Other claims from this paper (6)
Mechanismobservedoriginal resultmeasured

Claim · model-written summary

Initial breakages and lagging chromosomes involved nondisjunction of newly replicated sister chromatids preferentially at knobs.

Taxon
maizeZea mayst0
Outcome
occurrence of breakages and lagging chromosomese0
Qualifier
nondisjunction of newly replicated sister chromatidse0

Verbatim

e0

“The initial event responsible for the occurrence of breakages and lagging chromosomes was characterized by the nondisjunction of newly replicated sister chromatids, which was observed to occur preferentially at the knob level”

✓ located verbatim in the source · abstract, characters 546–771
t0

“maize”

✓ located verbatim in the source · title, characters 90–95

Title

Involvement of knob heterochromatin in mitotic abnormalities in germinating aged seeds of maize

A. Fluminhan; T. Kameya Genome 1997. doi:10.1139/g97-012

Other claims from this paper (4)
Mechanismauthor interpretationoriginal resultbasis n/a

Claim · model-written summary

The authors proposed intragenomic conflict between B chromosomes and heterochromatic knobs in maize landraces.

Taxon
maizeZea mayse1
Outcome
intragenomic conflicte0
Qualifier
Bs and heterochromatic knobse0

Verbatim

e0

“the negative relationship found between Bs and heterochromatic knobs allowed us to propose the existence of an intragenomic conflict between these elements.”

✓ located verbatim in the source · abstract, characters 1463–1619
e1

“native Argentinian and Bolivian maize landraces”

✓ located verbatim in the source · abstract, characters 232–279

Title

CAUSES AND CONSEQUENCES OF DNA CONTENT VARIATION IN ZEA

G.E. González; M.F. Realini; M.F. Fourastié; et al. Journal of Basic and Applied Genetics 2022. doi:10.35407/bag.2022.33.01.03

Other claims from this paper (10)
Mechanismhypothesisoriginal resultmeasured

Claim · model-written summary

The repeat units in knobs likely promote unequal crossing over, enabling rapid knob expansion.

Taxon
maizeZea mayst0
Outcome
rapid knob expansione0
Qualifier
unequal crossing overe0

Verbatim

t0

“maize”

✓ located verbatim in the source · title, characters 71–76
e0

“These repeat units likely promote unequal crossing over, enabling rapid knob expansion”

✓ located verbatim in the source · abstract, characters 1395–1481

Title

Higher order repeat structures reflect diverging evolutionary paths in maize centromeres and knobs

Rebecca D. Piri; Mingyu Wang; M. Cinta Romay; et al. Genome biology 2026. doi:10.1186/s13059-026-03993-4

Other claims from this paper (9)
Mechanismauthor interpretationoriginal resultnegativemeasured

Claim · model-written summary

The B drive mechanism causes detrimental effects through adherence of heterochromatic knobs and A centromeres at the mitosis preceding sperm development

Taxon
maizeZea mayst0
Outcome
detrimental effectse5
Qualifier
adherence of heterochromatic knobs and apparently A centromeres at the mitosis preceding sperm developmente5

Verbatim

t0

“maize”

✓ located verbatim in the source · title, characters 67–72
e5

“Collectively, the results reveal two backgrounds in which the B drive mechanism is not confined to this chromosome causing detrimental effects by adherence of heterochromatic knobs and apparently A centromeres at the mitosis preceding sperm development”

✓ located verbatim in the source · abstract, characters 1148–1400

Title

Aneuploidy and ploidy variation conditioned by the B chromosome of maize

Patrice S. Albert; Hua Yang; Zhi Gao; et al. Heredity 2025. doi:10.1038/s41437-025-00764-y

Other claims from this paper (5)
Mechanismauthor interpretationoriginal resultmeasured

Claim · model-written summary

The absence of hybridization signals in all maize knobs indicates that these heterochromatic regions were lost during Z. perennis genome evolution.

Taxon
maizeZea mayse7
Outcome
absence of hybridization signals in all maize knobse7
Qualifier
heterochromatic regions were lost during the Z. perennis genome evolutione7

Verbatim

e7

“the absence of hybridization signals in all maize knobs indicate that these heterochromatic regions were lost during the Z. perennis genome evolution”

✓ located verbatim in the source · abstract, characters 1666–1815

Title

Genomic affinities revealed by GISH suggests intergenomic restructuring between parental genomes of the paleopolyploid genus Zea

Graciela Esther González; Lidia Poggio Genome 2015. doi:10.1139/gen-2015-0081

Other claims from this paper (9)
Mechanismauthor interpretationoriginal resultmeasured

Claim · model-written summary

The authors attribute the 12-F amplification to unequal crossing over.

Taxon
MaizeZea mayst0
Outcome
amplification in the culture 12-Fe0
Qualifier
unequal crossing overe0

Verbatim

e0

“The finding of unequal crossing over in the cultures supports the conclusion that the amplification in the culture 12-F would be derived from this mechanism”

✓ located verbatim in the source · abstract, characters 1122–1278
t0

“Alterations in Heterochromatic Knobs in Maize Callus Culture by Breakage-Fusion-Bridge Cycle and Unequal Crossing Over”

✓ located verbatim in the source · title, characters 0–118

Title

Alterations in Heterochromatic Knobs in Maize Callus Culture by Breakage-Fusion-Bridge Cycle and Unequal Crossing Over

Janay A. Santos-Serejo; José R. Gardingo; Mateus Mondin; et al. Cytogenetic and Genome Research 2018. doi:10.1159/000488067

Other claims from this paper (4)
Mechanismobservedoriginal resultmeasured

Claim · model-written summary

Collicles form from mucilage canal bridges over vascular bundles.

Taxon
Cycadt0
Organ / stage
vascular bundlese0
Outcome
colliclese0
Qualifier
connecting mucilage canal ‘bridges’e0

Verbatim

e0

“The knobs, referred to as collicles, were found to be the result of connecting mucilage canal ‘bridges’ over vascular bundles, connecting mucilage canals situated between adjacent parallel vascular bundles”

✓ located verbatim in the source · abstract, characters 157–362
t0

“Cycad collicles”

✓ located verbatim in the source · title, characters 0–15

Title

Cycad collicles (“leaflet nodules”)

N. Grobbelaar; P.J. Robbertse South African Journal of Botany 2012. doi:10.1016/j.sajb.2012.02.008

Other claims from this paper (1)
Mechanismhypothesisoriginal resultbasis n/a

Claim · model-written summary

The NAC strands or knobs of quiescent cells are likely the counterpart of the two NORs.

Taxon
Zea maysZea mayst0
Outcome
NAC strands or knobse0
Qualifier
likely to be the counterpart of the 2 NORse0

Verbatim

t0

“during early germination of Zea mays L.”

✓ located verbatim in the source · title, characters 96–135
e0

“The NAC strands or knobs of the quiescent cells are likely to be the counterpart of the 2 NORs of this species”

✓ located verbatim in the source · abstract, characters 928–1038

Title

Three‐dimensional electron microscopy of the nucleolus and nucleolus‐associated chromatin (NAC) during early germination of Zea mays L.

Patrick Motte; Roger Deltour; Henri Mosen; et al. Biology of the Cell 1988. doi:10.1111/j.1768-322x.1988.tb00707.x

Other claims from this paper (10)
Mechanismhypothesisoriginal resultbasis n/a

Claim · model-written summary

The authors suggest that non-nucleolar transcriptional units may code for hnRNA and 23 nm knobs may represent informofers or hnRNA particles.

Taxon
Zea maysZea mayst0
Gene
genes coding for the heterodisperse nuclear RNA (hnRNA)e0
Outcome
non-nucleolar transcriptional unitse0
Qualifier
may corresponde0

Verbatim

t0

“Zea mays”

✓ located verbatim in the source · title, characters 79–87
e0

“These non-nucleolar transcriptional units may correspond to genes coding for the heterodisperse nuclear RNA (hnRNA) and the knobs of 23 nm could be related to informofers or hnRNA particles.”

✓ located verbatim in the source · abstract, characters 1306–1496

Title

Organization of transcribed and nontranscribed chromatin in isolated nuclei of Zea mays root cells.

R Greimers; R Deltour PubMed 1981

Other claims from this paper (10)
Mechanismauthor interpretationoriginal resultbasis n/a

Claim · model-written summary

Red sheath color, large grain size and triangular fruitcase in teosinte appear to reflect adaptation of particular teosinte populations rather than maize introgression.

Taxon
teosintee2
Outcome
Red sheath color, large grain size, triangular fruitcasee2
Qualifier
reflect the adaptation of particular teosinte populationse2

Verbatim

e2

“Red sheath color, large grain size, triangular fruitcase -and the presence of internal chromosome knobs, all characters attributed to maize introgression into teosinte, appear rather to reflect the adaptation of particular teosinte populations”

✓ located verbatim in the source · abstract, characters 254–497

Title

Maize Introgression Into Teosinte-A Reappraisal

John F. Doebley Annals of the Missouri Botanical Garden 1984. doi:10.2307/2399247

Other claims from this paper (1)
Mechanismhypothesisoriginal resultmeasured

Claim · model-written summary

The authors proposed that a substance secreted by dying leaf-nodule bacteria induces knob formation and may contribute to leaf nodules.

Interactor
leaf-nodule-bacteriae0symbiont
Outcome
formation of the knobse0
Qualifier
a substance, secreted by the leaf-nodule-bacteriae0

Not reportedTaxon

Verbatim

e0

“It is probable that the formation of the knobs is due to a substance, secreted by the leaf-nodule-bacteria, which cluster on the growing point and die by the treatment of antibiotic or of heat, and that this knob-forming substance may also acts on the formation of leaf nodules to some extent”

✓ located verbatim in the source · abstract, characters 1018–1310

Title

Studies on the Leaf Nodules V The Formation of Knobs by the Effect of Antibiotics on theArdisia crispa andA. punctata

Tamotsu YAMADA Shokubutsugaku Zasshi 1955. doi:10.15281/jplantres1887.68.267

Other claims from this paper (8)
Mechanismauthor interpretationreview summarypositivebasis n/a

Claim · model-written summary

Simple vegetative propagation made the four fruit trees preadapted for early domestication.

Taxon
Olive, grape, date, and fige0
Outcome
preadapted for domesticatione0
Qualifier
vegetatively propagated by simple techniques (cuttings, basal knobs, suckers)e0

Verbatim

e0

“Olive, grape, date, and fig can be vegetatively propagated by simple techniques (cuttings, basal knobs, suckers) and were thus preadapted for domestication early in the development of agriculture.”

✓ located verbatim in the source · abstract, characters 713–909

Title

Beginnings of Fruit Growing in the Old World

Daniel Zohary; Pinhas Spiegel-Roy Science 1975. doi:10.1126/science.187.4174.319

Other claims from this paper (7)

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