Claim · model-written summary
Two extracts of endophytic fungi from Annonaceae were inhibitory against M. tuberculosis H37Rv.
- Taxon
- AnnonaceaeAnnonaceaee0
- Interactor
- M. tuberculosis H37Rv
Mycobacterium tuberculosise1pathogen - Outcome
- two against M. tuberculosis H37Rve1
- Value
- twoe1
Verbatim
e0“endophytic fungi isolated from Philippine endemic Annonaceae plants”
e1“Twenty-three extracts were found to be inhibitory against ESKAPE pathogens, two against M. tuberculosis H37Rv, and 18 demonstrated free-radical scavenging properties”
Title
Micah Theresse Fajardo; Gabrielsony Mendoza; Hans Christian Arturo; et al. Studies in Fungi 2026. doi:10.48130/sif-0026-0005
Other claims from this paper (11)
- Observation Twenty-three extracts of endophytic fungi from Annonaceae inhibited ESKAPE pathogens.
- Observation Eighteen extracts of endophytic fungi from Annonaceae showed free-radical scavenging properties.
- Observation The BRFT extract from Chromolaenicola sp. showed strong anti-ESKAPE activity.
- Observation BRFT extract from Diaporthe longicolla inhibited M. tuberculosis H37Rv by 90% at 64 µg/mL.
- Observation BRFT extract from Endomelanconiopsis sp. inhibited M. tuberculosis H37Rv by 96% at 64 µg/mL.
- Observation The ZM extract from Chaetomium sp. showed radical scavenging activity comparable to BHT.
- Intervention effect BRFT supported the highest metabolite production among the tested media.
- Observation Mycochemical screening revealed anthrones, terpenes, sterols and indoles as major constituents of the extracts.
- Observation Chromolaenicola sp. and D. longicolla are first records from O. cumingiana.
- Observation Endomelanconiopsis sp. is a first record from A. cagayanensis.
- Observation Morphological and ITS-based phylogenetic analysis identified 11 distinct endophytic fungi as sources of the bioactive extracts.