Claim · model-written summary
2-CEES significantly perturbed amino acid, nucleic acid and carbohydrate metabolism in Bryum argenteum.
- Taxon
- Bryum argenteum
Bryum argenteume1 - Treatment
- 2-CEESe1
- Outcome
- amino acid, nucleic acid, carbohydratee1
- Direction
- perturbede1
Not reportedComparator
Verbatim
e1“Pathway enrichment analysis of differentially expressed metabolites (DEMs) indicated that 2-CEES significantly perturbed amino acid, nucleic acid, carbohydrate, and lipid metabolism in Bryum argenteum and Physcomitrella patens”
Title
Sheng Zheng; Hua Tan; Qian Fu; et al. Environmental Toxicology and Chemistry 2026. doi:10.1093/etojnl/vgag058
Other claims from this paper (11)
- Intervention effect 2-CEES exposure caused significant morphological changes in bryophytes.
- Intervention effect 2-CEES markedly disrupted the photosynthetic activity of Physcomitrella patens.
- Intervention effect 2-CEES markedly disrupted the photosynthetic activity of Taxiphyllum taxirameum.
- Intervention effect 2-CEES at 600 mg/m³ for 72 hr produced pronounced changes in metabolite expression across all three bryophytes.
- Intervention effect 2-CEES significantly perturbed lipid metabolism in Bryum argenteum.
- Intervention effect 2-CEES significantly perturbed amino acid, nucleic acid and carbohydrate metabolism in Physcomitrella patens.
- Intervention effect 2-CEES significantly perturbed lipid metabolism in Physcomitrella patens.
- Intervention effect 2-CEES caused primary disruptions in lipid metabolism, terpenoid and polyketide metabolism, and membrane transport in Taxiphyllum taxirameum.
- Association Aberrant synthesis of L-Glutamyl-tRNA(Glu) may correlate with impaired chlorophyll production in bryophytes.
- Observation Significant changes of Gamma-Glutamyl-beta-(isoxazolin-5-on-2-yl)alanine, Trans-zeatin riboside and Cytidine occurred in bryophytes exposed to 600 mg/m³ 2-CEES, suggesting potential as micro- and trace biochemical indicators of agent-induced stress.
- Mechanism Molecular docking suggests 2-CEES binds key enzymes (glutathione S-transferase and Glu-tRNA synthetase) through hydrogen bonds, interfering with substrate-binding activity and disrupting metabolic pathways.