By organism › Green plants › Orobanchaceae › Cistanche tubulosa

Observationobservedoriginal resultmeasured

Claim · model-written summary

The complete echinacoside biosynthetic pathway was elucidated in Cistanche tubulosa.

Taxon: Cistanche tubulosaCistanche tubulosae0
Outcome: complete ECH biosynthetic pathwaye0

Verbatim

e0
“Here, we elucidate the complete ECH biosynthetic pathway in the medicinal plant Cistanche tubulosa”
✓ located verbatim in the source · abstract, characters 187–285

Title

Complete pathway elucidation of echinacoside in Cistanche tubulosa and de novo biosynthesis of phenylethanoid glycosides

Wenqian Huang; Yaru Yan; Weisheng Tian; et al. Nature Communications 2025. doi:10.1038/s41467-025-56243-9

Other claims from this paper (5)

Observationobservedoriginal resultmeasured

Claim · model-written summary

Fourteen related genes were cloned and functionally characterized in Cistanche tubulosa.

Taxon: Cistanche tubulosaCistanche tubulosae0
Outcome: cloned and functionally characterizede1
Value: 14 related genese1

Verbatim

e0
“Here, we elucidate the complete ECH biosynthetic pathway in the medicinal plant Cistanche tubulosa”
✓ located verbatim in the source · abstract, characters 187–285

e1
“In total, 14 related genes are cloned and functionally characterized”
✓ located verbatim in the source · abstract, characters 287–355

Title

Complete pathway elucidation of echinacoside in Cistanche tubulosa and de novo biosynthesis of phenylethanoid glycosides

Wenqian Huang; Yaru Yan; Weisheng Tian; et al. Nature Communications 2025. doi:10.1038/s41467-025-56243-9

Other claims from this paper (5)

Observationobservedoriginal resultmeasured

Claim · model-written summary

Two upstream pathways for tyrosol biosynthesis from L-tyrosine were identified.

Taxon: Cistanche tubulosaCistanche tubulosae0
Compound: L-tyrosinee2
Outcome: upstream pathways for tyrosol biosynthesise2
Value: Two upstream pathwayse2

Verbatim

e0
“Here, we elucidate the complete ECH biosynthetic pathway in the medicinal plant Cistanche tubulosa”
✓ located verbatim in the source · abstract, characters 187–285

e2
“Two upstream pathways for tyrosol biosynthesis from L-tyrosine are identified”
✓ located verbatim in the source · abstract, characters 357–434

Title

Complete pathway elucidation of echinacoside in Cistanche tubulosa and de novo biosynthesis of phenylethanoid glycosides

Wenqian Huang; Yaru Yan; Weisheng Tian; et al. Nature Communications 2025. doi:10.1038/s41467-025-56243-9

Other claims from this paper (5)

Observationobservedoriginal resultmeasured

Claim · model-written summary

A downstream assembly process from tyrosol to echinacoside was identified, including sequential glucosylation, acylation, hydroxylation and rhamnosylation.

Taxon: Cistanche tubulosaCistanche tubulosae0
Outcome: downstream assembly process from tyrosol to ECHe3
Qualifier: sequential glucosylation, acylation, hydroxylation, and rhamnosylatione3

Verbatim

e0
“Here, we elucidate the complete ECH biosynthetic pathway in the medicinal plant Cistanche tubulosa”
✓ located verbatim in the source · abstract, characters 187–285

e3
“a distinct downstream assembly process from tyrosol to ECH is revealed that includes sequential glucosylation, acylation, hydroxylation, and rhamnosylation to form acteoside”
✓ located verbatim in the source · abstract, characters 604–777

Title

Complete pathway elucidation of echinacoside in Cistanche tubulosa and de novo biosynthesis of phenylethanoid glycosides

Wenqian Huang; Yaru Yan; Weisheng Tian; et al. Nature Communications 2025. doi:10.1038/s41467-025-56243-9

Other claims from this paper (5)

Observationobservedoriginal resultmeasured

Claim · model-written summary

A final glucosylation converts acteoside to echinacoside.

Taxon: Cistanche tubulosaCistanche tubulosae0
Outcome: final glucosylation converting acteoside to ECHe4

Verbatim

e0
“Here, we elucidate the complete ECH biosynthetic pathway in the medicinal plant Cistanche tubulosa”
✓ located verbatim in the source · abstract, characters 187–285

e4
“a final glucosylation converting acteoside to ECH”
✓ located verbatim in the source · abstract, characters 793–842

Title

Complete pathway elucidation of echinacoside in Cistanche tubulosa and de novo biosynthesis of phenylethanoid glycosides

Wenqian Huang; Yaru Yan; Weisheng Tian; et al. Nature Communications 2025. doi:10.1038/s41467-025-56243-9

Other claims from this paper (5)

Observationobservedoriginal resultmeasured

Claim · model-written summary

Heterologous expression in tobacco gave de novo synthesis of 23 phenylethanoid glycoside derivatives.

Taxon: Cistanche tubulosaCistanche tubulosae0
Treatment: heterologous expression of different combinations of the functional genese5
Outcome: de novo synthesis of 23 PhG derivativese5
Value: 23 PhG derivativese5
Qualifier: in tobaccoe5

Verbatim

e0
“Here, we elucidate the complete ECH biosynthetic pathway in the medicinal plant Cistanche tubulosa”
✓ located verbatim in the source · abstract, characters 187–285

e5
“the de novo synthesis of 23 PhG derivatives is achieved via the heterologous expression of different combinations of the functional genes in tobacco”
✓ located verbatim in the source · abstract, characters 857–1005

Title

Complete pathway elucidation of echinacoside in Cistanche tubulosa and de novo biosynthesis of phenylethanoid glycosides

Wenqian Huang; Yaru Yan; Weisheng Tian; et al. Nature Communications 2025. doi:10.1038/s41467-025-56243-9

Other claims from this paper (5)

Observationobservedoriginal resultmeasured

Claim · model-written summary

Predicted parasite-associated bacteria had more genes linked to plant growth promotion, salt–alkali stress resistance and substance metabolism.

Taxon: Cistanche tubulosaCistanche tubulosat0
Interactor: Tamarix chinensisTamarix chinensist0host
Outcome: genes in plant growth promotion, salt‒alkali stress resistance, and substance metabolisme0
Direction: moree0

Verbatim

e0
“the predicted bacterial communities of the parasite-associated microbiota contain more genes in plant growth promotion, salt‒alkali stress resistance, and substance metabolism”
✓ located verbatim in the source · abstract, characters 1124–1299

t0
“Cistanche tubulosa shapes the bacterial community structure and functional composition of the salt-tolerant host Tamarix chinensis”
✓ located verbatim in the source · title, characters 16–146

Title

Parasitic plant Cistanche tubulosa shapes the bacterial community structure and functional composition of the salt-tolerant host Tamarix chinensis across different parasitic statuses

Luyao Tang; Xiaoshan Liu; Shuhong Lin; et al. Environmental Microbiome 2025. doi:10.1186/s40793-025-00746-x

Other claims from this paper (8)

Associationobservedoriginal resultpositivemeasured

Claim · model-written summary

C. tubulosa dry weight per plant was relatively high in low-salinity soil.

Taxon: C. tubulosaCistanche tubulosae0
Outcome: dry weight per plante0
Direction: relatively highe0
Setting: low salinity soile0

Verbatim

e0
“the dry weight per plant of C. tubulosa was relatively high in low salinity soil”
✓ located verbatim in the source · abstract, characters 471–551

Title

Influence of planting region and soil chemical properties on medicinal compound contents in Cistanche tubulosa

Xinhong Wang; Xiaojun Ma; Lulu Li; et al. Bioscience Journal 2025. doi:10.14393/bj-v41n0a2025-67978

Other claims from this paper (10)

Association Echinacoside content increased under high salinity.
Association Verbascoside content increased under high salinity.
Association Individual soil pH showed no visible effect on dry weight or three measured compounds.
Association The salinity and pH interaction significantly affected mannitol content alone.
Association Under slight salinity, mannitol content was unaffected by pH.
Association Under severe salinity, high pH markedly reduced mannitol content.
Association In saline loam, dry weight per plant was lower.
Association In saline loam, planting density was higher.
Mechanism The authors infer that loam water and fertilizer retention can increase yield per area.
Recommendation The authors recommend high C. tubulosa seed dosage and moderate soil salinity for simultaneous yield and quality improvement.

Associationobservedoriginal resultmeasured

Claim · model-written summary

Echinacoside content increased under high salinity.

Taxon: Cistanche tubulosaCistanche tubulosat0
Outcome: echinacosidee0
Direction: increasede0
Setting: high salinity conditionse0

Verbatim

e0
“under high salinity conditions, echinacoside and verbascoside contents increased”
✓ located verbatim in the source · abstract, characters 562–642

t0
“Cistanche tubulosa”
✓ located verbatim in the source · title, characters 92–110

Title

Influence of planting region and soil chemical properties on medicinal compound contents in Cistanche tubulosa

Xinhong Wang; Xiaojun Ma; Lulu Li; et al. Bioscience Journal 2025. doi:10.14393/bj-v41n0a2025-67978

Other claims from this paper (10)

Association C. tubulosa dry weight per plant was relatively high in low-salinity soil.
Association Verbascoside content increased under high salinity.
Association Individual soil pH showed no visible effect on dry weight or three measured compounds.
Association The salinity and pH interaction significantly affected mannitol content alone.
Association Under slight salinity, mannitol content was unaffected by pH.
Association Under severe salinity, high pH markedly reduced mannitol content.
Association In saline loam, dry weight per plant was lower.
Association In saline loam, planting density was higher.
Mechanism The authors infer that loam water and fertilizer retention can increase yield per area.
Recommendation The authors recommend high C. tubulosa seed dosage and moderate soil salinity for simultaneous yield and quality improvement.

Associationobservedoriginal resultmeasured

Claim · model-written summary

Verbascoside content increased under high salinity.

Taxon: Cistanche tubulosaCistanche tubulosat0
Outcome: verbascosidee0
Direction: increasede0
Setting: high salinity conditionse0

Verbatim

e0
“under high salinity conditions, echinacoside and verbascoside contents increased”
✓ located verbatim in the source · abstract, characters 562–642

t0
“Cistanche tubulosa”
✓ located verbatim in the source · title, characters 92–110

Title

Influence of planting region and soil chemical properties on medicinal compound contents in Cistanche tubulosa

Xinhong Wang; Xiaojun Ma; Lulu Li; et al. Bioscience Journal 2025. doi:10.14393/bj-v41n0a2025-67978

Other claims from this paper (10)

Association C. tubulosa dry weight per plant was relatively high in low-salinity soil.
Association Echinacoside content increased under high salinity.
Association Individual soil pH showed no visible effect on dry weight or three measured compounds.
Association The salinity and pH interaction significantly affected mannitol content alone.
Association Under slight salinity, mannitol content was unaffected by pH.
Association Under severe salinity, high pH markedly reduced mannitol content.
Association In saline loam, dry weight per plant was lower.
Association In saline loam, planting density was higher.
Mechanism The authors infer that loam water and fertilizer retention can increase yield per area.
Recommendation The authors recommend high C. tubulosa seed dosage and moderate soil salinity for simultaneous yield and quality improvement.

Cistanche tubulosa 400 claims

400 claims