Claim · model-written summary
Thiazole phenoxypyridines improved maize tolerance under fomesafen toxicity stress to varying degrees at 10 mg/kg.
- Treatment
- thiazole phenoxypyridinese0
- Outcome
- maize tolerance under fomesafen toxicity stresse0
- Direction
- improvee0
- Qualifier
- at a dose of 10 mg·kg−1e0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
e0“thiazole phenoxypyridines could improve maize tolerance under fomesafen toxicity stress to varying degrees at a dose of 10 mg·kg−1”
Title
Li-Xia Zhao; Min-Lei Yin; Qing-Rui Wang; et al. Biomolecules 2019. doi:10.3390/biom9100514
Other claims from this paper (7)
- Intervention effect Compound 4i gave the best protective effects among the tested thiazole phenoxypyridines in maize.
- Intervention effect After compound 4i treatment, average recovery rates of the maize growth index exceeded 72%.
- Intervention effect After compound 4i treatment, glutathione content in maize markedly increased by 167%.
- Intervention effect After compound 4i treatment, glutathione S-transferase activity in maize was almost 163% of the fomesafen-treated group.
- Intervention effect After compound 4i treatment, the activity of PPO, the main target enzyme of fomesafen, recovered to 93% of the control level.
- Mechanism Molecular docking indicated that compound 4i could compete with fomesafen to bind the herbicide target enzyme, consequently attaining herbicide detoxification.
- Recommendation The authors suggest compound 4i could be developed as a potential safener to protect maize from fomesafen.