Claim · model-written summary
The authors suggest compound 4i could be developed as a potential safener to protect maize from fomesafen.
- Outcome
- potential safenere0
Zea maysNot reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“compound 4i could be developed as a potential safener to protect maize from fomesafen”
Title
Li-Xia Zhao; Min-Lei Yin; Qing-Rui Wang; et al. Biomolecules 2019. doi:10.3390/biom9100514
Other claims from this paper (7)
- Intervention effect Thiazole phenoxypyridines improved maize tolerance under fomesafen toxicity stress to varying degrees at 10 mg/kg.
- Intervention effect Compound 4i gave the best protective effects among the tested thiazole phenoxypyridines in maize.
- Intervention effect After compound 4i treatment, average recovery rates of the maize growth index exceeded 72%.
- Intervention effect After compound 4i treatment, glutathione content in maize markedly increased by 167%.
- Intervention effect After compound 4i treatment, glutathione S-transferase activity in maize was almost 163% of the fomesafen-treated group.
- Intervention effect After compound 4i treatment, the activity of PPO, the main target enzyme of fomesafen, recovered to 93% of the control level.
- Mechanism Molecular docking indicated that compound 4i could compete with fomesafen to bind the herbicide target enzyme, consequently attaining herbicide detoxification.