Claim · model-written summary
After compound 4i treatment, the activity of PPO, the main target enzyme of fomesafen, recovered to 93% of the control level.
- Treatment
- compound 4ie0
- Gene
- PPOe0
- Outcome
- activity of PPOe0
- Direction
- recoverede0
- Value
- 93%e0
- Comparator
- controle0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleSettingQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
t0“Maize”
e0“after being treated by compound 4i, the activity of PPO, the main target enzyme of fomesafen, recovered to 93% of the control level”
Title
Li-Xia Zhao; Min-Lei Yin; Qing-Rui Wang; et al. Biomolecules 2019. doi:10.3390/biom9100514
Other claims from this paper (7)
- Intervention effect Thiazole phenoxypyridines improved maize tolerance under fomesafen toxicity stress to varying degrees at 10 mg/kg.
- Intervention effect Compound 4i gave the best protective effects among the tested thiazole phenoxypyridines in maize.
- Intervention effect After compound 4i treatment, average recovery rates of the maize growth index exceeded 72%.
- Intervention effect After compound 4i treatment, glutathione content in maize markedly increased by 167%.
- Intervention effect After compound 4i treatment, glutathione S-transferase activity in maize was almost 163% of the fomesafen-treated group.
- Mechanism Molecular docking indicated that compound 4i could compete with fomesafen to bind the herbicide target enzyme, consequently attaining herbicide detoxification.
- Recommendation The authors suggest compound 4i could be developed as a potential safener to protect maize from fomesafen.