Claim · model-written summary
Loss-of-function of MAN3 decreased cadmium accumulation and tolerance.
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianat0 - Treatment
- loss-of-function of MAN3e2
- Gene
- MAN3e2
- Outcome
- Cd accumulation and tolerancee2
- Direction
- decreasede2
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
t0“in Arabidopsis thaliana”
e2“loss-of-function of MAN3 resulted in decreased Cd accumulation and tolerance”
Title
Jian Chen; Libo Yang; Ju Gu; et al. New Phytologist 2014. doi:10.1111/nph.13101
Other claims from this paper (6)
- Intervention effect Overexpression of MAN3 enhanced cadmium accumulation and tolerance.
- Association Enhanced cadmium accumulation and tolerance in xcd1-D was associated with GSH-dependent, Cd-activated synthesis of phytochelatins.
- Intervention effect Cd stress increased mannose content in cell walls through MAN3 expression and mannanase activity.
- Intervention effect Mannose treatment rescued the Cd-sensitive phenotype of the xcd1-2 mutant.
- Intervention effect Mannose treatment improved cadmium tolerance of wild-type plants.
- Mechanism Mannose-mediated cadmium accumulation and tolerance depend on GSH-dependent PC concentrations through coordinated control of PC synthesis genes.