Intervention effectmodel-written summary

Virus-induced gene silencing of the barley HvLRRK-6H compromised leaf defense against F. graminearum.

A claim from A Pathogen-Responsive Leucine Rich Receptor Like Kinase Contributes to Fusarium Resistance in Cereals · 2018

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Virus-induced gene silencing of the barley HvLRRK-6H compromised leaf defense against F. graminearum.

Organ / stage
leafe3
Treatment
Virus-induced gene silencing (VIGS)e3
Interactor
F. graminearumFusarium graminearume3pathogen
Gene
HvLRRK-6He3
Outcome
leaf defensee3
Direction
compromisede3

Not reportedMaterialCompoundSecond interactorSecond interactor roleComparatorSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Hordeum vulgare
Hordeum vulgare · TaxonJackyM59 · CC BY-SA 4.0 · Wikimedia Commons ↗
Fusarium graminearum
Fusarium graminearum · InteractorScot Nelson from Honolulu, USA · CC0 · Wikimedia Commons ↗

Verbatim

e3

“Virus-induced gene silencing (VIGS) of the barley HvLRRK-6H compromised leaf defense against F. graminearum”

✓ located verbatim in the source · abstract, characters 977–1084

Title

A Pathogen-Responsive Leucine Rich Receptor Like Kinase Contributes to Fusarium Resistance in Cereals

Ganesh Thapa; Lokanadha R. Gunupuru; James G. Hehir; et al. Frontiers in Plant Science 2018. doi:10.3389/fpls.2018.00867

Other claims from this paper (8)

Record rev-e53d5e9b72b6ec104d907c6532e0097382e37c343b0ff2bfc88f9a8f310eb5c6 · schema claims-v0.9 · position 3 in the model’s answer

loss of function · Fusarium graminearum · Hordeum vulgare (barley)Positive and negative results

8 papers: 3 positive, 5 negative or no effect

4 papers in the same direction as this claim · 3 in the opposite direction

  1. positive
    Deletion of FgABC1 and FgABC3 impeded virulence of F. graminearum on wheat, barley and maize.

    Identification of ABC Transporter Genes of Fusarium graminearum with Roles in Azole Tolerance and/or Virulence · 2013

    Opposite direction

  2. positive
    Disruption of FgFSR1 reduced F. graminearum virulence on barley.

    FSR1 Is Essential for Virulence and Female Fertility in Fusarium verticillioides and F. graminearum · 2006

    Opposite direction

  3. positive
    Three metabolites rose more after tri5 inoculation than after toxin-producing isolate inoculation.

    Differential metabolic response of barley genotypes, varying in resistance, to trichothecene‐producing and ‐nonproducing ( tri5 − ) isolates of Fusarium graminearum · 2011 · compared with trichothecene‐producing isolate

    Opposite direction

  4. negative
    ICS suppression compromised barley resistance to Fusarium graminearum.

    Isochorismate‐based salicylic acid biosynthesis confers basal resistance to Fusarium graminearum in barley · 2018

    Same direction

  5. no effect
    Deletion of FgAP1 or FgATF1 had no significant effect on DON production by Fusarium graminearum.

    FgSKN 7 and FgATF 1 have overlapping functions in ascosporogenesis, pathogenesis and stress responses in F usarium graminearum · 2014

    Same direction

  6. no effect
    Deleting GzICL1 did not cause a defect in virulence of G. zeae on barley.

    Roles of the Glyoxylate and Methylcitrate Cycles in Sexual Development and Virulence in the Cereal PathogenGibberella zeae · 2009

    Same direction

  7. no effect
    Deleting FgFRP1 in F. graminearum did not reduce infection of aerial plant parts.

    The FRP1 F‐box gene has different functions in sexuality, pathogenicity and metabolism in three fungal pathogens · 2011

    Same direction

See all 8 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.

Functional evidence on HvLRRK-6H

Claims that state a gain or loss of function of this gene and what it did to a trait, compared with wild type or a control.

HvLRRK-6H

Hordeum vulgare (barley)1 paper · 1 traitTested in one paper only

Only one paper in the store tests this gene's function in Hordeum vulgare (barley).

Disease resistance1 paper

  1. Promotes
    Virus-induced gene silencing of the barley HvLRRK-6H compromised leaf defense against F. graminearum.

    A Pathogen-Responsive Leucine Rich Receptor Like Kinase Contributes to Fusarium Resistance in Cereals · 2018

    loss of function → less of the traitThis claim

The program reads each claim's manipulation and the direction of the trait, and from them the gene's role (gain and more, or loss and less, means it promotes the trait). Roles are read by program from each claim's wording. Pairs of papers on the same host, gene and trait were checked claim by claim by two model readers; a pair is marked checked only when both accept it. Gene layer v0.8, 21 trait classes.