By organism › Green plants › Ebenaceae › Diospyros comorensis

Observationobservedoriginal resultmeasured

Claim · model-written summary

Leaf extracts had total phenolic content of 29,693.02 ± 3493.75 mg GAE/100 g DW, higher than HPLC quantification.

Taxon: Diospyros comorensisDiospyros comorensist0
Outcome: total phenolic content (TPC)e0
Direction: highere0
Value: 29,693.02 ± 3493.75 mg GAE/100 g DWe0
Comparator: total phenolics quantified by HPLCe0

Verbatim

e0
“The extracts showed a total phenolic content (TPC) of 29,693.02 ± 3493.75 mg GAE/100 g DW (Folin–Ciocalteu method), which was markedly higher than the total phenolics quantified by HPLC (3743.12 ± 457.32 mg/100 g DW, representing 76.38% of the total bioactive fraction).”
✓ located verbatim in the source · abstract, characters 871–1141

t0
“Diospyros comorensis”
✓ located verbatim in the source · title, characters 165–185

Title

Sustainable Use of Natural Resources and Traditional Medicine in Tropical Countries: Uncovering the Main Antioxidant Compounds and Antihypertensive Potential of the Diospyros comorensis Leaves as Health-Promoting Food Application for Local Population

Ahmed Ali; Dario Donno; Zoarilala Rinah Razafindrakoto; et al. Plants 2026. doi:10.3390/plants15111757

Other claims from this paper (10)

Observation HPLC quantified total phenolics at 3743.12 ± 457.32 mg/100 g DW.
Observation HPLC-quantified phenolics represented 76.38% of the total bioactive fraction.
Observation Ellagic acid was the main quantified constituent at 56.36%.
Observation Both leaf extracts exhibited marked antioxidant capacity.
Intervention effect MDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 3.83 ± 0.81 µg/mL.
Intervention effect DDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 4.87 ± 0.79 µg/mL.
Observation Neither extract showed acute toxicity in Swiss mice.
Mechanism Identified compounds may contribute to antioxidant and pharmacological effects.
Recommendation The results support traditional use of leaves for high blood pressure management.
Recommendation Further studies are needed on mechanisms and bioactive substances.

Observationobservedoriginal resultmeasured

Claim · model-written summary

HPLC quantified total phenolics at 3743.12 ± 457.32 mg/100 g DW.

Taxon: Diospyros comorensisDiospyros comorensist0
Outcome: total phenolicse0
Value: 3743.12 ± 457.32 mg/100 g DWe0

Not reportedDirection

Verbatim

e0
“total phenolics quantified by HPLC (3743.12 ± 457.32 mg/100 g DW, representing 76.38% of the total bioactive fraction)”
✓ located verbatim in the source · abstract, characters 1022–1140

t0
“Diospyros comorensis”
✓ located verbatim in the source · title, characters 165–185

Title

Sustainable Use of Natural Resources and Traditional Medicine in Tropical Countries: Uncovering the Main Antioxidant Compounds and Antihypertensive Potential of the Diospyros comorensis Leaves as Health-Promoting Food Application for Local Population

Ahmed Ali; Dario Donno; Zoarilala Rinah Razafindrakoto; et al. Plants 2026. doi:10.3390/plants15111757

Other claims from this paper (10)

Observation Leaf extracts had total phenolic content of 29,693.02 ± 3493.75 mg GAE/100 g DW, higher than HPLC quantification.
Observation HPLC-quantified phenolics represented 76.38% of the total bioactive fraction.
Observation Ellagic acid was the main quantified constituent at 56.36%.
Observation Both leaf extracts exhibited marked antioxidant capacity.
Intervention effect MDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 3.83 ± 0.81 µg/mL.
Intervention effect DDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 4.87 ± 0.79 µg/mL.
Observation Neither extract showed acute toxicity in Swiss mice.
Mechanism Identified compounds may contribute to antioxidant and pharmacological effects.
Recommendation The results support traditional use of leaves for high blood pressure management.
Recommendation Further studies are needed on mechanisms and bioactive substances.

Observationobservedoriginal resultmeasured

Claim · model-written summary

HPLC-quantified phenolics represented 76.38% of the total bioactive fraction.

Taxon: Diospyros comorensisDiospyros comorensist0
Outcome: total phenolicse0
Value: 76.38%e0
Qualifier: of the total bioactive fractione0

Verbatim

e0
“total phenolics quantified by HPLC (3743.12 ± 457.32 mg/100 g DW, representing 76.38% of the total bioactive fraction)”
✓ located verbatim in the source · abstract, characters 1022–1140

t0
“Diospyros comorensis”
✓ located verbatim in the source · title, characters 165–185

Title

Sustainable Use of Natural Resources and Traditional Medicine in Tropical Countries: Uncovering the Main Antioxidant Compounds and Antihypertensive Potential of the Diospyros comorensis Leaves as Health-Promoting Food Application for Local Population

Ahmed Ali; Dario Donno; Zoarilala Rinah Razafindrakoto; et al. Plants 2026. doi:10.3390/plants15111757

Other claims from this paper (10)

Observation Leaf extracts had total phenolic content of 29,693.02 ± 3493.75 mg GAE/100 g DW, higher than HPLC quantification.
Observation HPLC quantified total phenolics at 3743.12 ± 457.32 mg/100 g DW.
Observation Ellagic acid was the main quantified constituent at 56.36%.
Observation Both leaf extracts exhibited marked antioxidant capacity.
Intervention effect MDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 3.83 ± 0.81 µg/mL.
Intervention effect DDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 4.87 ± 0.79 µg/mL.
Observation Neither extract showed acute toxicity in Swiss mice.
Mechanism Identified compounds may contribute to antioxidant and pharmacological effects.
Recommendation The results support traditional use of leaves for high blood pressure management.
Recommendation Further studies are needed on mechanisms and bioactive substances.

Observationobservedoriginal resultmeasured

Claim · model-written summary

Ellagic acid was the main quantified constituent at 56.36%.

Taxon: Diospyros comorensisDiospyros comorensist0
Outcome: ellagic acide0
Direction: maine0
Value: 56.36%e0

Verbatim

e0
“Among the quantified constituents, ellagic acid (56.36%) was the main compound.”
✓ located verbatim in the source · abstract, characters 1142–1221

t0
“Diospyros comorensis”
✓ located verbatim in the source · title, characters 165–185

Title

Sustainable Use of Natural Resources and Traditional Medicine in Tropical Countries: Uncovering the Main Antioxidant Compounds and Antihypertensive Potential of the Diospyros comorensis Leaves as Health-Promoting Food Application for Local Population

Ahmed Ali; Dario Donno; Zoarilala Rinah Razafindrakoto; et al. Plants 2026. doi:10.3390/plants15111757

Other claims from this paper (10)

Observation Leaf extracts had total phenolic content of 29,693.02 ± 3493.75 mg GAE/100 g DW, higher than HPLC quantification.
Observation HPLC quantified total phenolics at 3743.12 ± 457.32 mg/100 g DW.
Observation HPLC-quantified phenolics represented 76.38% of the total bioactive fraction.
Observation Both leaf extracts exhibited marked antioxidant capacity.
Intervention effect MDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 3.83 ± 0.81 µg/mL.
Intervention effect DDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 4.87 ± 0.79 µg/mL.
Observation Neither extract showed acute toxicity in Swiss mice.
Mechanism Identified compounds may contribute to antioxidant and pharmacological effects.
Recommendation The results support traditional use of leaves for high blood pressure management.
Recommendation Further studies are needed on mechanisms and bioactive substances.

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Both leaf extracts exhibited marked antioxidant capacity.

Taxon: Diospyros comorensisDiospyros comorensist0
Outcome: antioxidant capacitye0
Qualifier: markede0

Verbatim

e0
“Both extracts exhibited marked antioxidant capacity”
✓ located verbatim in the source · abstract, characters 1222–1273

t0
“Diospyros comorensis”
✓ located verbatim in the source · title, characters 165–185

Title

Sustainable Use of Natural Resources and Traditional Medicine in Tropical Countries: Uncovering the Main Antioxidant Compounds and Antihypertensive Potential of the Diospyros comorensis Leaves as Health-Promoting Food Application for Local Population

Ahmed Ali; Dario Donno; Zoarilala Rinah Razafindrakoto; et al. Plants 2026. doi:10.3390/plants15111757

Other claims from this paper (10)

Observation Leaf extracts had total phenolic content of 29,693.02 ± 3493.75 mg GAE/100 g DW, higher than HPLC quantification.
Observation HPLC quantified total phenolics at 3743.12 ± 457.32 mg/100 g DW.
Observation HPLC-quantified phenolics represented 76.38% of the total bioactive fraction.
Observation Ellagic acid was the main quantified constituent at 56.36%.
Intervention effect MDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 3.83 ± 0.81 µg/mL.
Intervention effect DDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 4.87 ± 0.79 µg/mL.
Observation Neither extract showed acute toxicity in Swiss mice.
Mechanism Identified compounds may contribute to antioxidant and pharmacological effects.
Recommendation The results support traditional use of leaves for high blood pressure management.
Recommendation Further studies are needed on mechanisms and bioactive substances.

Mechanismhypothesisoriginal resultbasis n/a

Claim · model-written summary

Identified compounds may contribute to antioxidant and pharmacological effects.

Taxon: Diospyros comorensisDiospyros comorensist0
Outcome: antioxidant and pharmacological effectse0
Qualifier: identified compounds may be involvede0

Verbatim

e0
“The identified compounds may be involved in the observed antioxidant and pharmacological effects.”
✓ located verbatim in the source · abstract, characters 1498–1595

t0
“Diospyros comorensis”
✓ located verbatim in the source · title, characters 165–185

Title

Sustainable Use of Natural Resources and Traditional Medicine in Tropical Countries: Uncovering the Main Antioxidant Compounds and Antihypertensive Potential of the Diospyros comorensis Leaves as Health-Promoting Food Application for Local Population

Ahmed Ali; Dario Donno; Zoarilala Rinah Razafindrakoto; et al. Plants 2026. doi:10.3390/plants15111757

Other claims from this paper (10)

Observation Leaf extracts had total phenolic content of 29,693.02 ± 3493.75 mg GAE/100 g DW, higher than HPLC quantification.
Observation HPLC quantified total phenolics at 3743.12 ± 457.32 mg/100 g DW.
Observation HPLC-quantified phenolics represented 76.38% of the total bioactive fraction.
Observation Ellagic acid was the main quantified constituent at 56.36%.
Observation Both leaf extracts exhibited marked antioxidant capacity.
Intervention effect MDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 3.83 ± 0.81 µg/mL.
Intervention effect DDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 4.87 ± 0.79 µg/mL.
Observation Neither extract showed acute toxicity in Swiss mice.
Recommendation The results support traditional use of leaves for high blood pressure management.
Recommendation Further studies are needed on mechanisms and bioactive substances.

Recommendationauthor interpretationoriginal resultpositivebasis n/a

Claim · model-written summary

The results support traditional use of leaves for high blood pressure management.

Taxon: D. comorensisDiospyros comorensise0
Outcome: traditional use of D. comorensis leaves in managing high blood pressuree0

Verbatim

e0
“These results show experimental evidence useful to support the traditional use of D. comorensis leaves in managing high blood pressure and highlight the antihypertensive potential of this Comorian endemic species.”
✓ located verbatim in the source · abstract, characters 1596–1809

Title

Sustainable Use of Natural Resources and Traditional Medicine in Tropical Countries: Uncovering the Main Antioxidant Compounds and Antihypertensive Potential of the Diospyros comorensis Leaves as Health-Promoting Food Application for Local Population

Ahmed Ali; Dario Donno; Zoarilala Rinah Razafindrakoto; et al. Plants 2026. doi:10.3390/plants15111757

Other claims from this paper (10)

Observation Leaf extracts had total phenolic content of 29,693.02 ± 3493.75 mg GAE/100 g DW, higher than HPLC quantification.
Observation HPLC quantified total phenolics at 3743.12 ± 457.32 mg/100 g DW.
Observation HPLC-quantified phenolics represented 76.38% of the total bioactive fraction.
Observation Ellagic acid was the main quantified constituent at 56.36%.
Observation Both leaf extracts exhibited marked antioxidant capacity.
Intervention effect MDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 3.83 ± 0.81 µg/mL.
Intervention effect DDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 4.87 ± 0.79 µg/mL.
Observation Neither extract showed acute toxicity in Swiss mice.
Mechanism Identified compounds may contribute to antioxidant and pharmacological effects.
Recommendation Further studies are needed on mechanisms and bioactive substances.

Recommendationauthor interpretationoriginal resultbasis n/a

Claim · model-written summary

Further studies are needed on mechanisms and bioactive substances.

Taxon: Diospyros comorensisDiospyros comorensist0
Outcome: characterize the biological mechanisms involved and relative bioactive substancese0

Verbatim

e0
“Further studies are necessary to characterize the biological mechanisms involved and relative bioactive substances.”
✓ located verbatim in the source · abstract, characters 1810–1925

t0
“Diospyros comorensis”
✓ located verbatim in the source · title, characters 165–185

Title

Sustainable Use of Natural Resources and Traditional Medicine in Tropical Countries: Uncovering the Main Antioxidant Compounds and Antihypertensive Potential of the Diospyros comorensis Leaves as Health-Promoting Food Application for Local Population

Ahmed Ali; Dario Donno; Zoarilala Rinah Razafindrakoto; et al. Plants 2026. doi:10.3390/plants15111757

Other claims from this paper (10)

Observation Leaf extracts had total phenolic content of 29,693.02 ± 3493.75 mg GAE/100 g DW, higher than HPLC quantification.
Observation HPLC quantified total phenolics at 3743.12 ± 457.32 mg/100 g DW.
Observation HPLC-quantified phenolics represented 76.38% of the total bioactive fraction.
Observation Ellagic acid was the main quantified constituent at 56.36%.
Observation Both leaf extracts exhibited marked antioxidant capacity.
Intervention effect MDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 3.83 ± 0.81 µg/mL.
Intervention effect DDCR caused significant vasorelaxation in precontracted rat aorta with EC50 of 4.87 ± 0.79 µg/mL.
Observation Neither extract showed acute toxicity in Swiss mice.
Mechanism Identified compounds may contribute to antioxidant and pharmacological effects.
Recommendation The results support traditional use of leaves for high blood pressure management.

Observationobservedoriginal resultmeasured

Claim · model-written summary

D. comorensis was assessed Near Threatened.

Taxon: D. comorensisDiospyros comorensise0
Outcome: Near Threatenede0

Verbatim

e0
“one as Near Threatened (D. comorensis Hiern)”
✓ located verbatim in the source · abstract, characters 991–1035

Title

Taxonomic studies of Diospyros L. (Ebenaceae) from the Malagasy region. IV. Synoptic revision of the Squamosa group in Madagascar and the Comoro Islands

George E. Schatz; Porter P. Lowry Adansonia 2020. doi:10.5252/adansonia2020v42a10

Other claims from this paper (5)

Observation The revision recognizes nine Squamosa-group Diospyros species.
Observation Six new Diospyros species are described and illustrated.
Observation Five Diospyros species were assessed Endangered.
Observation D. antakaranae was assessed Vulnerable.
Observation D. sennenii and D. squamosa were assessed Least Concern.

Diospyros comorensis 9 claims

9 claims