Abstract
The antagonistic fungus Simplicillium lamellicola BCP has been developed as a microbial biopesticide that effectively controls the development of various plant diseases caused by both pathogenic bacteria and pathogenic fungi. Antibacterial bioassay-directed fractionation was used to isolate mannosyl lipids from S. lamellicola BCP, and the structures of these compounds were elucidated using spectral analysis and chemical degradation. Three novel mannosyl lipids were characterized and identified as halymecins F and G and (3R,5R)-3-O-β-D-mannosyl-3,5-dihydrodecanoic acid. Massoia lactone and (3R, 5R)-3-hydroxydecan-5-olide were also isolated from S. lamellicola BCP. The three novel compounds inhibited the growth of the majority of phytopathogenic bacteria that were tested, and halymecin F displayed the strongest antibacterial activity. Agrobacterium tumefaciens was the most sensitive to the three novel compounds, with IC₅₀ values ranging from 1.58 to 24.8 μg/mL. The ethyl acetate extract of the fermentation broth from the antagonistic fungus effectively reduced the bacterial wilt caused by Ralstonia solanacearum on tomato seedlings. These results indicate that S. lamellicola BCP suppresses the development of plant bacterial diseases through the production of antibacterial metabolites.
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Claims 7
Claim · model-written summary
Three novel mannosyl lipids were identified from S. lamellicola BCP.
- Outcome
- halymecins F and G and (3R,5R)-3-O-β-D-mannosyl-3,5-dihydrodecanoic acide0
Not reportedTaxonDirection
Verbatim
e0“Three novel mannosyl lipids were characterized and identified as halymecins F and G and (3R,5R)-3-O-β-D-mannosyl-3,5-dihydrodecanoic acid”
Claim · model-written summary
Massoia lactone and (3R, 5R)-3-hydroxydecan-5-olide were isolated from S. lamellicola BCP.
- Taxon
- S. lamellicola BCPSimplicillium lamellicolae0
- Outcome
- Massoia lactone and (3R, 5R)-3-hydroxydecan-5-olidee0
Not reportedDirection
Verbatim
e0“Massoia lactone and (3R, 5R)-3-hydroxydecan-5-olide were also isolated from S. lamellicola BCP”
Claim · model-written summary
The three novel compounds inhibited most tested phytopathogenic bacteria.
- Taxon
- phytopathogenic bacteriae0
- Treatment
- three novel compoundse0
- Outcome
- growth of the majority of phytopathogenic bacteriae0
- Direction
- inhibitede0
Not reportedComparator
Verbatim
e0“The three novel compounds inhibited the growth of the majority of phytopathogenic bacteria that were tested”
Claim · model-written summary
Halymecin F had the strongest antibacterial activity among the compounds.
Not reportedTaxon
Verbatim
e0“halymecin F displayed the strongest antibacterial activity”
Claim · model-written summary
Agrobacterium tumefaciens was the most sensitive bacterium to the three novel compounds, with IC₅₀ values of 1.58 to 24.8 μg/mL.
- Taxon
- Agrobacterium tumefaciens
Agrobacterium tumefaciense0 - Treatment
- three novel compoundse0
- Outcome
- sensitivee0
- Direction
- most sensitivee0
- Value
- 1.58 to 24.8 μg/mLe0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Agrobacterium tumefaciens was the most sensitive to the three novel compounds, with IC₅₀ values ranging from 1.58 to 24.8 μg/mL”
Claim · model-written summary
Ethyl acetate extract from the antagonistic fungus reduced Ralstonia solanacearum bacterial wilt on tomato seedlings.
- Taxon
- tomato
Solanum lycopersicume0 - Treatment
- ethyl acetate extract of the fermentation broth from the antagonistic funguse0
- Interactor
- Ralstonia solanacearum
Ralstonia solanacearume0pathogen - Second interactor
- Simplicillium lamellicola BCPSimplicillium lamellicolat0biocontrol_agent
- Outcome
- bacterial wilte0
- Direction
- reducede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The ethyl acetate extract of the fermentation broth from the antagonistic fungus effectively reduced the bacterial wilt caused by Ralstonia solanacearum on tomato seedlings”
t0“Simplicillium lamellicola BCP”
Claim · model-written summary
The authors infer that S. lamellicola BCP suppresses plant bacterial diseases by producing antibacterial metabolites.
- Taxon
- S. lamellicola BCPSimplicillium lamellicolae0
- Outcome
- development of plant bacterial diseasese0
- Direction
- suppressese0
- Qualifier
- production of antibacterial metabolitese0
Verbatim
e0“S. lamellicola BCP suppresses the development of plant bacterial diseases through the production of antibacterial metabolites”
The same questions in other papers
ethyl acetate · Ralstonia solanacearum · Solanum lycopersicum (tomato)Results agree
2 papers in the same direction as this paper
- positive
- positive
botanical · Ralstonia solanacearum · Solanum lycopersicum (tomato)Positive and negative results
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See all 31 papers →processing · Ralstonia solanacearum · Solanum lycopersicum (tomato)Results agree
3 papers in the same direction as this paper
- positive
- positive
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Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.