Abstract
Deoxynivalenol (DON), a trichothecene mycotoxin, could lead to cytotoxicity in both animal bodies and plant seed cells. Ozone degradation technology has been applied to DON control. However, the safety and quality of the contaminated grain after DON degradation are largely obscured. In this work, we evaluated the cytotoxicity of ozone-treated DON through seed germination experiments and cytotoxicity tests. Cell experiments showed that the inhibition rate of HepG2 viability gradually increased within the concentrations of 1-10 mg/L of DON, alongside which an IC50 (half maximal inhibitory concentration) of 9.1 mg/L was determined. In contrast, degrading DON had no significant inhibitory effect on cell growth. Moreover, a 1-10 mg/L concentration of DON increased production of a large amount of reactive oxygen radicals in HepG2, with obvious fluorescence color development. However, fluorescence intensity decreased after DON degradation. Further, DON at a concentration of >1 mg/L significantly inhibited the germination of mung bean seeds, whereas no significant inhibition of their germination or growth were observed if DON degraded. Changes in total protein content, fatty acid value, and starch content were insignificant in wheat samples suffering ozone degradation, compared to the untreated group. Lastly, the ozone-treated wheat samples exhibited higher tenacity and whiteness. Together, our study indicated that the toxicity of DON-contaminated wheat was significantly reduced after ozone degradation.
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Claims 7
Claim · model-written summary
DON above 1 mg/L significantly inhibited mung bean seed germination.
- Taxon
- mung bean
.jpg?width=60)
Vigna radiatae0 - Treatment
- DON at a concentration of >1 mg/Le0
- Outcome
- germination of mung bean seedse0
- Direction
- inhibitede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
.jpg?width=500)
Verbatim
e0“DON at a concentration of >1 mg/L significantly inhibited the germination of mung bean seeds”
Claim · model-written summary
Degraded DON did not significantly inhibit mung bean germination or growth.
- Taxon
- mung beanVigna radiatae1
- Treatment
- DON degradede0
- Outcome
- germination or growthe0
- Direction
- no significant inhibitione0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“no significant inhibition of their germination or growth were observed if DON degraded”
e1“mung bean seeds”
Claim · model-written summary
Ozone degradation produced no significant change in total protein content of wheat.
- Taxon
- wheat
Triticum aestivume0 - Treatment
- ozone degradatione0
- Outcome
- total protein contente0
- Direction
- insignificante0
- Comparator
- untreated groupe0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Changes in total protein content, fatty acid value, and starch content were insignificant in wheat samples suffering ozone degradation, compared to the untreated group.”
Claim · model-written summary
Ozone degradation produced no significant change in wheat fatty acid value.
- Taxon
- wheatTriticum aestivume0
- Treatment
- ozone degradatione0
- Outcome
- fatty acid valuee0
- Direction
- insignificante0
- Comparator
- untreated groupe0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Changes in total protein content, fatty acid value, and starch content were insignificant in wheat samples suffering ozone degradation, compared to the untreated group.”
Claim · model-written summary
Ozone degradation produced no significant change in wheat starch content.
- Taxon
- wheatTriticum aestivume0
- Treatment
- ozone degradatione0
- Outcome
- starch contente0
- Direction
- insignificante0
- Comparator
- untreated groupe0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Changes in total protein content, fatty acid value, and starch content were insignificant in wheat samples suffering ozone degradation, compared to the untreated group.”
Claim · model-written summary
Ozone-treated wheat samples had higher tenacity and whiteness.
- Taxon
- wheatTriticum aestivume0
- Treatment
- ozone-treatede0
- Outcome
- tenacity and whitenesse0
- Direction
- highere0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the ozone-treated wheat samples exhibited higher tenacity and whiteness”
Claim · model-written summary
Ozone degradation significantly reduced toxicity of DON-contaminated wheat.
- Taxon
- wheatTriticum aestivume0
- Treatment
- ozone degradatione0
- Outcome
- toxicity of DON-contaminated wheate0
- Direction
- reducede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the toxicity of DON-contaminated wheat was significantly reduced after ozone degradation”
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