Chromobacteriaceae 11 claims

Claim · model-written summary

Compound 1 inhibited violacein production by 84.92% in the bacterial bioassay.

Taxon

Chromobacterium violaceum ATCC 12472Chromobacterium violaceum ATCC 12472e0

Material

1e0

Treatment

250 μMe0

Outcome

violacein inhibition ratese0

Value

84.92%e0

Verbatim

e0

“In bioassays against Chromobacterium violaceum ATCC 12472, compounds 1, 4, 6, 7 and 9 exhibited potential quorum sensing (QS) inhibitory activity at 250 μM, with violacein inhibition rates of 84.92%, 74.96%, 70.47%, 71.43% and 76.87%, respectively.”

Claim · model-written summary

Compound 4 inhibited violacein production by 74.96% in the bacterial bioassay.

Taxon

Chromobacterium violaceum ATCC 12472Chromobacterium violaceum ATCC 12472e0

Material

4e0

Treatment

250 μMe0

Outcome

violacein inhibition ratese0

Value

74.96%e0

Verbatim

e0

“In bioassays against Chromobacterium violaceum ATCC 12472, compounds 1, 4, 6, 7 and 9 exhibited potential quorum sensing (QS) inhibitory activity at 250 μM, with violacein inhibition rates of 84.92%, 74.96%, 70.47%, 71.43% and 76.87%, respectively.”

Claim · model-written summary

Compound 6 inhibited violacein production by 70.47% in the bacterial bioassay.

Taxon

Chromobacterium violaceum ATCC 12472Chromobacterium violaceum ATCC 12472e0

Material

6e0

Treatment

250 μMe0

Outcome

violacein inhibition ratese0

Value

70.47%e0

Verbatim

e0

“In bioassays against Chromobacterium violaceum ATCC 12472, compounds 1, 4, 6, 7 and 9 exhibited potential quorum sensing (QS) inhibitory activity at 250 μM, with violacein inhibition rates of 84.92%, 74.96%, 70.47%, 71.43% and 76.87%, respectively.”

Claim · model-written summary

Compound 7 inhibited violacein production by 71.43% in the bacterial bioassay.

Taxon

Chromobacterium violaceum ATCC 12472Chromobacterium violaceum ATCC 12472e0

Material

7e0

Treatment

250 μMe0

Outcome

violacein inhibition ratese0

Value

71.43%e0

Verbatim

e0

“In bioassays against Chromobacterium violaceum ATCC 12472, compounds 1, 4, 6, 7 and 9 exhibited potential quorum sensing (QS) inhibitory activity at 250 μM, with violacein inhibition rates of 84.92%, 74.96%, 70.47%, 71.43% and 76.87%, respectively.”

Claim · model-written summary

Compound 9 inhibited violacein production by 76.87% in the bacterial bioassay.

Taxon

Chromobacterium violaceum ATCC 12472Chromobacterium violaceum ATCC 12472e0

Material

9e0

Treatment

250 μMe0

Outcome

violacein inhibition ratese0

Value

76.87%e0

Verbatim

e0

“In bioassays against Chromobacterium violaceum ATCC 12472, compounds 1, 4, 6, 7 and 9 exhibited potential quorum sensing (QS) inhibitory activity at 250 μM, with violacein inhibition rates of 84.92%, 74.96%, 70.47%, 71.43% and 76.87%, respectively.”

Claim · model-written summary

The three new compounds inhibited bacterial biofilm formation with dose.

Taxon

C. violaceum ATCC 12472Chromobacterium violaceume0

Material

the three new compoundse0

Outcome

biofilm formatione0

Direction

inhibitede0

Verbatim

e0

“Furthermore, the three new compounds dose-dependently inhibited biofilm formation and significantly suppressed both swimming and swarming motility of C. violaceum ATCC 12472.”

Claim · model-written summary

The three new compounds suppressed bacterial swimming and swarming motility.

Taxon

C. violaceum ATCC 12472Chromobacterium violaceume0

Material

the three new compoundse0

Outcome

swimming and swarming motilitye0

Direction

suppressede0

Verbatim

e0

“Furthermore, the three new compounds dose-dependently inhibited biofilm formation and significantly suppressed both swimming and swarming motility of C. violaceum ATCC 12472.”

Claim · model-written summary

Mutation of the chi54 locus eliminated chitinase production in Chromobacterium sp. strain C61.

Taxon

Chromobacterium sp. strain C61Chromobacterium sp.e0

Treatment

mutation of chi54e1

Gene

chi54e1

Outcome

chitinase productione1

Direction

eliminatede1

Not reportedComparator

Verbatim

e0

“Chromobacterium sp. strain C61 displays”

e1

“mutation of chi54 eliminated chitinase production”

Claim · model-written summary

Adding chitin to the culture medium increased extracellular enzyme production and chi54 transcript expression in the wild-type strain.

Taxon

Chromobacterium sp. strain C61Chromobacterium sp.e0

Material

wild-type straine1

Treatment

chitin was added to the culture mediume1

Gene

chi54e1

Outcome

Production of the extracellular enzyme and expression of the chi54 transcripte1

Direction

increasede1

Not reportedComparator

Verbatim

e0

“Chromobacterium sp. strain C61 displays”

e1

“Production of the extracellular enzyme and expression of the chi54 transcript were increased in the wild-type strain when chitin was added to the culture medium”

Claim · model-written summary

The authors suggest that production of both extracellular chitinase Chi54 and chromobactomycin can contribute, in an interconnected way, to suppression of plant disease by strain C61.

Taxon

Chromobacterium sp. strain C61Chromobacterium sp.e1

Gene

Chi54e1

Compound

chromobactomycine1

Outcome

suppression of plant diseasee1

Verbatim

e1

“the production of both the extracellular chitinase Chi54 and the newly identified antibiotic chromobactomycin can contribute, in an interconnected way, to the suppression of plant disease by Chromobacterium sp. strain C61”