Arthrodermataceae 9 claims

family · order Onygenales · 5 taxa · NCBI Taxonomy ↗

5 entries

Trichophyton mentagrophytes4 claims · 3 papers Microsporum canis2 claims · 1 paper Microsporum audouinii1 claim · 1 paper Trichophyton interdigitale1 claim · 1 paper Trichophyton rubrum1 claim · 1 paper

9 claims

Open in search (filters, sorting) →

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

P. ecuadorense essential oil had very strong activity against Trichophyton rubrum with an MIC of 62.5 μg/mL.

Taxon: Trichophyton rubrumTrichophyton rubrume1
Material: ATCC 28188e1
Treatment: essential oil from P. ecuadorensee0
Outcome: MICe1
Value: 62.5 μg/mLe1
Qualifier: very strong activitye1

Not reportedComparatorDirection

Verbatim

e0
“The essential oil from P. ecuadorense”
✓ located verbatim in the source · abstract, characters 390–427

e1
“a very strong activity against Trichophyton rubrum (ATCC 28188) and Trichophyton mentagrophytes (ATCC 28185) with an MIC of 62.5 μg/mL in both cases”
✓ located verbatim in the source · abstract, characters 551–699

Title

Phytochemical profile, antimicrobial and antioxidant activities of essential oil extracted from Ecuadorian species Piper ecuadorense sodiro

Eduardo Valarezo; Paola Flores-Maza; Luis Cartuche; et al. Natural Product Research 2020. doi:10.1080/14786419.2020.1813138

Other claims from this paper (10)

Observation Forty-four compounds representing 98.65% of Piper ecuadorense essential oil were identified.
Observation Bicyclogermacrene constituted 12.98% of the essential oil.
Observation 3-Thujopsanone constituted 11.59% of the essential oil.
Observation Alpha-phellandrene constituted 6.89% of the essential oil.
Observation (E)-Nerolidol constituted 6.88% of the essential oil.
Observation Delta-elemene constituted 6.83% of the essential oil.
Observation Shyobunol constituted 5.79% of the essential oil.
Intervention effect P. ecuadorense essential oil had strong activity against Staphylococcus aureus with an MIC of 250 μg/mL.
Intervention effect P. ecuadorense essential oil had very strong activity against Trichophyton mentagrophytes with an MIC of 62.5 μg/mL.
Observation The essential oil showed an antioxidant IC50 of 1.81 ± 0.09 mg/mL in the ABTS assay.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

P. ecuadorense essential oil had very strong activity against Trichophyton mentagrophytes with an MIC of 62.5 μg/mL.

Taxon: Trichophyton mentagrophytesTrichophyton mentagrophytese1
Material: ATCC 28185e1
Treatment: essential oil from P. ecuadorensee0
Outcome: MICe1
Value: 62.5 μg/mLe1
Qualifier: very strong activitye1

Not reportedComparatorDirection

Verbatim

e0
“The essential oil from P. ecuadorense”
✓ located verbatim in the source · abstract, characters 390–427

e1
“a very strong activity against Trichophyton rubrum (ATCC 28188) and Trichophyton mentagrophytes (ATCC 28185) with an MIC of 62.5 μg/mL in both cases”
✓ located verbatim in the source · abstract, characters 551–699

Title

Phytochemical profile, antimicrobial and antioxidant activities of essential oil extracted from Ecuadorian species Piper ecuadorense sodiro

Eduardo Valarezo; Paola Flores-Maza; Luis Cartuche; et al. Natural Product Research 2020. doi:10.1080/14786419.2020.1813138

Other claims from this paper (10)

Observation Forty-four compounds representing 98.65% of Piper ecuadorense essential oil were identified.
Observation Bicyclogermacrene constituted 12.98% of the essential oil.
Observation 3-Thujopsanone constituted 11.59% of the essential oil.
Observation Alpha-phellandrene constituted 6.89% of the essential oil.
Observation (E)-Nerolidol constituted 6.88% of the essential oil.
Observation Delta-elemene constituted 6.83% of the essential oil.
Observation Shyobunol constituted 5.79% of the essential oil.
Intervention effect P. ecuadorense essential oil had strong activity against Staphylococcus aureus with an MIC of 250 μg/mL.
Intervention effect P. ecuadorense essential oil had very strong activity against Trichophyton rubrum with an MIC of 62.5 μg/mL.
Observation The essential oil showed an antioxidant IC50 of 1.81 ± 0.09 mg/mL in the ABTS assay.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Methanolic extract showed antifungal activity against Microsporum canis.

Taxon: Microsporum canisMicrosporum canise0
Treatment: methanolic extracte0
Outcome: antifungal activitye0

Not reportedComparatorDirection

Verbatim

e0
“the methanolic extract exhibited antifungal activity against the investigated six pathogenic fungal strains: Aspergillus flavus, Aspergillus fumigatus, Candida albicans, Microsporum canis, Microsporum boulardii and Trichophyton mentagrophytes.”
✓ located verbatim in the source · abstract, characters 1146–1389

Title

Phytochemical Analysis and Antifungal bioactivity of Pulicaria undulata (L.) Methanolic Extract and Essential Oil

Nesma Helal; Nevin Ibrahim; Hemmat Khattab Egyptian Journal of Botany 2019. doi:10.21608/ejbo.2019.12259.1308

Other claims from this paper (19)

Observation Pulicaria aerial portions contain phenols, flavonoids and terpenoids.
Observation Pulicaria aerial portions contain saponins, alkaloids and glucosinolates.
Observation Pulicaria aerial portions contain cardiac glycosides.
Association Greater bioactive-compound accumulation in methanolic extract accompanied higher antioxidant capacity and IC50 than petroleum ether extract.
Observation GC-MS detected cyclotrisiloxane, hexamethyl-, cyclotetrasiloxane, octamethyl-, and cyclopentasiloxane, decamethyl in Pulicaria.
Observation GC-MS detected dodecanoic acid, methyl ester, tetrafluorophthalonitrile and gamma-Sitosterol.
Observation GC-MS detected nonacosane and the named octamethyl picenone constituent.
Observation GC-MS reported thiazolo[4,5-f]quinoline and 7-methyl-.
Intervention effect Methanolic extract showed antifungal activity against Aspergillus flavus.
Intervention effect Methanolic extract showed antifungal activity against Aspergillus fumigatus.
Intervention effect Methanolic extract showed antifungal activity against Candida albicans.
Intervention effect Methanolic extract showed antifungal activity against Microsporum boulardii.
Intervention effect Methanolic extract showed antifungal activity against Trichophyton mentagrophytes.
Intervention effect Methanolic extract was fungicidal against M. boulardii IFM 56403 and had safe cytotoxicity levels in this case.
Intervention effect Methanolic extract was fungicidal against T. mentagrophytes AUMC 11661 and had safe cytotoxicity levels in this case.
Intervention effect Methanolic extract was fungicidal against M. canis AUMC 11663 and had safe cytotoxicity levels in this case.
Intervention effect Methanolic extract was fungicidal against C. albicans AUMC 9142 and had safe cytotoxicity levels in this case.
Intervention effect Petroleum ether extract inhibited the tested fungi less efficiently.
Recommendation The authors propose Pulicaria as a promising antifungal source for medically important fungi.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Methanolic extract showed antifungal activity against Trichophyton mentagrophytes.

Taxon: Trichophyton mentagrophytesTrichophyton mentagrophytese0
Treatment: methanolic extracte0
Outcome: antifungal activitye0

Not reportedComparatorDirection

Verbatim

e0
“the methanolic extract exhibited antifungal activity against the investigated six pathogenic fungal strains: Aspergillus flavus, Aspergillus fumigatus, Candida albicans, Microsporum canis, Microsporum boulardii and Trichophyton mentagrophytes.”
✓ located verbatim in the source · abstract, characters 1146–1389

Title

Phytochemical Analysis and Antifungal bioactivity of Pulicaria undulata (L.) Methanolic Extract and Essential Oil

Nesma Helal; Nevin Ibrahim; Hemmat Khattab Egyptian Journal of Botany 2019. doi:10.21608/ejbo.2019.12259.1308

Other claims from this paper (19)

Observation Pulicaria aerial portions contain phenols, flavonoids and terpenoids.
Observation Pulicaria aerial portions contain saponins, alkaloids and glucosinolates.
Observation Pulicaria aerial portions contain cardiac glycosides.
Association Greater bioactive-compound accumulation in methanolic extract accompanied higher antioxidant capacity and IC50 than petroleum ether extract.
Observation GC-MS detected cyclotrisiloxane, hexamethyl-, cyclotetrasiloxane, octamethyl-, and cyclopentasiloxane, decamethyl in Pulicaria.
Observation GC-MS detected dodecanoic acid, methyl ester, tetrafluorophthalonitrile and gamma-Sitosterol.
Observation GC-MS detected nonacosane and the named octamethyl picenone constituent.
Observation GC-MS reported thiazolo[4,5-f]quinoline and 7-methyl-.
Intervention effect Methanolic extract showed antifungal activity against Aspergillus flavus.
Intervention effect Methanolic extract showed antifungal activity against Aspergillus fumigatus.
Intervention effect Methanolic extract showed antifungal activity against Candida albicans.
Intervention effect Methanolic extract showed antifungal activity against Microsporum canis.
Intervention effect Methanolic extract showed antifungal activity against Microsporum boulardii.
Intervention effect Methanolic extract was fungicidal against M. boulardii IFM 56403 and had safe cytotoxicity levels in this case.
Intervention effect Methanolic extract was fungicidal against T. mentagrophytes AUMC 11661 and had safe cytotoxicity levels in this case.
Intervention effect Methanolic extract was fungicidal against M. canis AUMC 11663 and had safe cytotoxicity levels in this case.
Intervention effect Methanolic extract was fungicidal against C. albicans AUMC 9142 and had safe cytotoxicity levels in this case.
Intervention effect Petroleum ether extract inhibited the tested fungi less efficiently.
Recommendation The authors propose Pulicaria as a promising antifungal source for medically important fungi.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Methanolic extract was fungicidal against T. mentagrophytes AUMC 11661 and had safe cytotoxicity levels in this case.

Taxon: T. mentagrophytesTrichophyton mentagrophytese0
Material: AUMC 11661e0
Treatment: methanolic extracte0
Outcome: fungicidal effecte0
Qualifier: safe levelse1

Not reportedComparatorDirection

Verbatim

e0
“the methanolic extract has demonstrated a fungicidal effect on M. boulardii IFM 56403, T. mentagrophytes AUMC 11661, M. canis AUMC 11663, and C. albicans AUMC 9142.”
✓ located verbatim in the source · abstract, characters 1504–1668

e1
“The cytotoxicity evaluation of the methanolic extract showed safe levels in case of these four fungal strains.”
✓ located verbatim in the source · abstract, characters 1669–1779

Title

Phytochemical Analysis and Antifungal bioactivity of Pulicaria undulata (L.) Methanolic Extract and Essential Oil

Nesma Helal; Nevin Ibrahim; Hemmat Khattab Egyptian Journal of Botany 2019. doi:10.21608/ejbo.2019.12259.1308

Other claims from this paper (19)

Observation Pulicaria aerial portions contain phenols, flavonoids and terpenoids.
Observation Pulicaria aerial portions contain saponins, alkaloids and glucosinolates.
Observation Pulicaria aerial portions contain cardiac glycosides.
Association Greater bioactive-compound accumulation in methanolic extract accompanied higher antioxidant capacity and IC50 than petroleum ether extract.
Observation GC-MS detected cyclotrisiloxane, hexamethyl-, cyclotetrasiloxane, octamethyl-, and cyclopentasiloxane, decamethyl in Pulicaria.
Observation GC-MS detected dodecanoic acid, methyl ester, tetrafluorophthalonitrile and gamma-Sitosterol.
Observation GC-MS detected nonacosane and the named octamethyl picenone constituent.
Observation GC-MS reported thiazolo[4,5-f]quinoline and 7-methyl-.
Intervention effect Methanolic extract showed antifungal activity against Aspergillus flavus.
Intervention effect Methanolic extract showed antifungal activity against Aspergillus fumigatus.
Intervention effect Methanolic extract showed antifungal activity against Candida albicans.
Intervention effect Methanolic extract showed antifungal activity against Microsporum canis.
Intervention effect Methanolic extract showed antifungal activity against Microsporum boulardii.
Intervention effect Methanolic extract showed antifungal activity against Trichophyton mentagrophytes.
Intervention effect Methanolic extract was fungicidal against M. boulardii IFM 56403 and had safe cytotoxicity levels in this case.
Intervention effect Methanolic extract was fungicidal against M. canis AUMC 11663 and had safe cytotoxicity levels in this case.
Intervention effect Methanolic extract was fungicidal against C. albicans AUMC 9142 and had safe cytotoxicity levels in this case.
Intervention effect Petroleum ether extract inhibited the tested fungi less efficiently.
Recommendation The authors propose Pulicaria as a promising antifungal source for medically important fungi.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Methanolic extract was fungicidal against M. canis AUMC 11663 and had safe cytotoxicity levels in this case.

Taxon: M. canisMicrosporum canise0
Material: AUMC 11663e0
Treatment: methanolic extracte0
Outcome: fungicidal effecte0
Qualifier: safe levelse1

Not reportedComparatorDirection

Verbatim

e0
“the methanolic extract has demonstrated a fungicidal effect on M. boulardii IFM 56403, T. mentagrophytes AUMC 11661, M. canis AUMC 11663, and C. albicans AUMC 9142.”
✓ located verbatim in the source · abstract, characters 1504–1668

e1
“The cytotoxicity evaluation of the methanolic extract showed safe levels in case of these four fungal strains.”
✓ located verbatim in the source · abstract, characters 1669–1779

Title

Phytochemical Analysis and Antifungal bioactivity of Pulicaria undulata (L.) Methanolic Extract and Essential Oil

Nesma Helal; Nevin Ibrahim; Hemmat Khattab Egyptian Journal of Botany 2019. doi:10.21608/ejbo.2019.12259.1308

Other claims from this paper (19)

Observation Pulicaria aerial portions contain phenols, flavonoids and terpenoids.
Observation Pulicaria aerial portions contain saponins, alkaloids and glucosinolates.
Observation Pulicaria aerial portions contain cardiac glycosides.
Association Greater bioactive-compound accumulation in methanolic extract accompanied higher antioxidant capacity and IC50 than petroleum ether extract.
Observation GC-MS detected cyclotrisiloxane, hexamethyl-, cyclotetrasiloxane, octamethyl-, and cyclopentasiloxane, decamethyl in Pulicaria.
Observation GC-MS detected dodecanoic acid, methyl ester, tetrafluorophthalonitrile and gamma-Sitosterol.
Observation GC-MS detected nonacosane and the named octamethyl picenone constituent.
Observation GC-MS reported thiazolo[4,5-f]quinoline and 7-methyl-.
Intervention effect Methanolic extract showed antifungal activity against Aspergillus flavus.
Intervention effect Methanolic extract showed antifungal activity against Aspergillus fumigatus.
Intervention effect Methanolic extract showed antifungal activity against Candida albicans.
Intervention effect Methanolic extract showed antifungal activity against Microsporum canis.
Intervention effect Methanolic extract showed antifungal activity against Microsporum boulardii.
Intervention effect Methanolic extract showed antifungal activity against Trichophyton mentagrophytes.
Intervention effect Methanolic extract was fungicidal against M. boulardii IFM 56403 and had safe cytotoxicity levels in this case.
Intervention effect Methanolic extract was fungicidal against T. mentagrophytes AUMC 11661 and had safe cytotoxicity levels in this case.
Intervention effect Methanolic extract was fungicidal against C. albicans AUMC 9142 and had safe cytotoxicity levels in this case.
Intervention effect Petroleum ether extract inhibited the tested fungi less efficiently.
Recommendation The authors propose Pulicaria as a promising antifungal source for medically important fungi.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

The water extract had higher antifungal activity against M. audouinii than other extracts, with minimum inhibitory concentration 16 μg/mL.

Taxon: M. audouiniiMicrosporum audouiniie0
Treatment: water extracte0
Outcome: antifungal activitiese0
Direction: highere0
Value: 16 μg/mLe0
Comparator: other extractse0

Verbatim

e0
“The water extract exhibited higher larvicidal (LD50 = 11.77 μg/mL), nematicidal (LD50 = 11.78 μg/mL), antifeedant (LD50 > 40 μg/mL), and antifungal activities (minimum inhibitory concentration: 16 μg/mL) against M. audouinii compared with the other extracts.”
✓ located verbatim in the source · abstract, characters 1355–1613

Title

Larvicidal, nematicidal, antifeedant and antifungal, antioxidant activities of Mentha spicata (Lamiaceae) root extracts

Abdullah Alaklabi; Ibrahim A. Arif; Anis Ahamed; et al. Tropical Journal of Pharmaceutical Research 2016. doi:10.4314/tjpr.v15i11.12

Other claims from this paper (7)

Observationobservedoriginal resultmeasured

Claim · model-written summary

Both oils showed marked antifungal activity against Trichophyton mentagrophytes.

Taxon: Trichophyton mentagrophytesTrichophyton mentagrophytese0
Outcome: marked antifungal activitye0

Verbatim

e0
“They also showed a marked antifungal activity against Trichophyton mentagrophytes, Cryptococcus neoformans, and Candida albicans”
✓ located verbatim in the source · abstract, characters 526–654

Title

Chemical Composition and Antimicrobial Activity of Essential Oils ofJasonia candicansandJ. montana

F. Hammerschmidt; Alice Clark; Fathy Soliman; et al. Planta Medica 1993. doi:10.1055/s-2006-959607

Other claims from this paper (8)

Observation Twenty-one volatile oil components were identified in J. candicans.
Observation Intermediol was the main constituent of J. candicans volatile oil.
Observation Fifty-eight essential oil components were characterized in J. montana.
Observation Camphor, borneol and bornyl acetate were major J. montana oil constituents.
Observation Chrysanthemol, intermediol and 1,8-cineole were major J. montana oil constituents.
Observation Both oils showed antibacterial activity against Bacillus subtilis.
Observation Both oils showed marked antifungal activity against Cryptococcus neoformans.
Observation Both oils showed marked antifungal activity against Candida albicans.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

The oil had strong antifungal activity against Trichophyton mentagrophytes var. interdigitale.

Taxon: Trichophyton mentagrophytes var. interdigitaleTrichophyton interdigitalee0
Treatment: oile0
Outcome: antifungal activitye0

Not reportedComparatorDirection

Verbatim

e0
“The oil was found to possess strong antifungal activity against Trichophyton mentagrophytes var. interdigitale and Candida albicans.”
✓ located verbatim in the source · abstract, characters 148–280

Title

The Essential Oil ofLippia alba(Mill.) N.E.Br.

Chris E. Fun; Anders Baerheim Svendsen Journal of Essential Oil Research 1990. doi:10.1080/10412905.1990.9697879

Other claims from this paper (4)

Observation Lippia alba oil contained 64.6% citral.
Observation Lippia alba oil contained 28.2% neral.
Observation Lippia alba oil contained 36.4% geranial.
Intervention effect The oil had strong antifungal activity against Candida albicans.