By organism › Fungi › Cytosporaceae

Observationobservedoriginal resultmeasured

Claim · model-written summary

Seven new mycoviruses were identified in 31 Cytospora chrysosperma strains from Xinjiang by metatranscriptomic sequencing, BLAST and RT-PCR.

Taxon: C. chrysospermaCytospora chrysospermae1
Interactor: mycovirusese1other
Outcome: Seven new mycoviruses were identifiede1
Value: Sevene1
Setting: Xinjiang Uygur autonomous regione1

Verbatim

e1
“mycoviruses associated with 31 strains of C. chrysosperma from Xinjiang Uygur autonomous region were identified by metatranscriptomic sequencing. Seven new mycoviruses were identified by BLAST and RT-PCR analysis”
✓ located verbatim in the source · abstract, characters 402–614

Title

Identification of Mycoviruses in Cytospora chrysosperma: Potential Biocontrol Agents for Walnut Canker

Yingjie Mi; Shaohua Chen; Kexin Liu; et al. Viruses 2025. doi:10.3390/v17020180

Other claims from this paper (3)

Intervention effectobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

Five mycoviruses (BcPV5, GVsp-XJ1, BVsp-XJ2, CrMV3, LfTV2) co-infecting C. chrysosperma strain WS-11 significantly reduced its colony growth rate and virulence.

Taxon: C. chrysospermaCytospora chrysospermae1
Treatment: co-infecte1
Interactor: BcPV5, GVsp-XJ1, BVsp-XJ2, CrMV3, and LfTV2e1other
Outcome: colony growth rate and virulencee1
Direction: reducee1

Not reportedComparator

Verbatim

e1
“BcPV5, GVsp-XJ1, BVsp-XJ2, CrMV3, and LfTV2 were found to co-infect C. chrysosperma strain WS-11 and significantly reduce both the colony growth rate and virulence of the host”
✓ located verbatim in the source · abstract, characters 920–1095

Title

Identification of Mycoviruses in Cytospora chrysosperma: Potential Biocontrol Agents for Walnut Canker

Yingjie Mi; Shaohua Chen; Kexin Liu; et al. Viruses 2025. doi:10.3390/v17020180

Other claims from this paper (3)

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

After co-culturing virus-free strain WS-FV with WS-11, the derivative strain also had decreased colony growth rate and virulence.

Taxon: Cytospora chrysospermaCytospora chrysospermat0
Treatment: co-culturing the virus-free WS-FV strain with WS-11e1
Outcome: colony growth rate and virulencee1
Direction: decreasede1
Comparator: virus-free WS-FV straine1

Verbatim

t0
“Cytospora chrysosperma”
✓ located verbatim in the source · title, characters 33–55

e1
“After co-culturing the virus-free WS-FV strain with WS-11, the colony growth rate and virulence of the derivative strain were also decreased”
✓ located verbatim in the source · abstract, characters 1097–1237

Title

Identification of Mycoviruses in Cytospora chrysosperma: Potential Biocontrol Agents for Walnut Canker

Yingjie Mi; Shaohua Chen; Kexin Liu; et al. Viruses 2025. doi:10.3390/v17020180

Other claims from this paper (3)

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Compound 4d had an in vitro EC50 of 0.21 mg/L against Valsa mali.

Taxon: Valsa maliCytospora malie1
Outcome: EC 50 valuese0
Value: 0.21e0

Verbatim

e0
“EC 50 values of 0.21, 0.95, 0.64, 1.33, and 0.66 mg L”
✓ located verbatim in the source · abstract, characters 623–676

e1
“against Valsa mali , Botrytis cinerea , Rhizoctonia solani , Fusarium graminearum , and Gaeumannomyces graminis”
✓ located verbatim in the source · abstract, characters 680–791

Title

Discovery of novel 4‐sulfur‐substituted pyrazol‐5‐yl‐benzamide derivatives containing amide/hydrazide/ester moieties as potential succinate dehydrogenase inhibitors

Yantao Li; Yuxin Mu; Jun Xiong; et al. Pest Management Science 2025. doi:10.1002/ps.8943

Other claims from this paper (9)

Observationobservedoriginal resultsimulated

Claim · model-written summary

CcCAP3 was predicted to be GPI-anchored.

Taxon: C. chrysospermaCytospora chrysospermae1
Gene: CcCAP3e0
Outcome: GPI-anchorede0

Not reportedDirection

Verbatim

e0
“CcCAP3 is predicted to be GPI-anchored”
✓ located verbatim in the source · abstract, characters 815–853

e1
“C. chrysosperma CAP family, CcCAP2 and CcCAP3”
✓ located verbatim in the source · abstract, characters 578–623

Title

The Virulence‐Associated CAP/PR1‐Like Proteins From Cytospora chrysosperma Target a Subunit of RNA Polymerase II to Suppress Plant Immunity

Zhu Han; Dianguang Xiong; Haoyu Wu; et al. Plant Cell & Environment 2025. doi:10.1111/pce.70289

Other claims from this paper (12)

Observation Deletion of CcCAP2 affected C. chrysosperma vegetative growth.
Observation Deletion of CcCAP3 affected C. chrysosperma vegetative growth.
Association CcCAP2 contributed to C. chrysosperma virulence during interaction with Populus euramericana.
Observation CcCAP2 was identified as a secreted glycoprotein.
Intervention effect Ectopic CcCAP2 expression in Nicotiana benthamiana promoted Botrytis cinerea infection.
Intervention effect Ectopic CcCAP2 expression in Nicotiana benthamiana inhibited immune-related gene expression.
Observation A poplar library screen gave the highest number of hits with RPB11.
Association CcCAP1 and CcCAP2 interacted with RPB11 in validation assays.
Intervention effect Silencing RPB11 caused a dwarf phenotype in the host plant.
Intervention effect Silencing RPB11 reduced fungal colonisation of the host plant.
Intervention effect Silencing RPB11 highly induced PR1 gene expression.
Mechanism The authors infer that CcCAP1 and CcCAP2 target plant RPB11 to suppress host immunity and facilitate infection.

Observationobservedoriginal resultmeasured

Claim · model-written summary

CcCAP2 was identified as a secreted glycoprotein.

Taxon: C. chrysospermaCytospora chrysospermae1
Gene: CcCAP2e0
Outcome: secreted glycoproteine0

Not reportedDirection

Verbatim

e0
“CcCAP2 is a secreted glycoprotein”
✓ located verbatim in the source · abstract, characters 855–888

e1
“C. chrysosperma CAP family, CcCAP2 and CcCAP3”
✓ located verbatim in the source · abstract, characters 578–623

Title

The Virulence‐Associated CAP/PR1‐Like Proteins From Cytospora chrysosperma Target a Subunit of RNA Polymerase II to Suppress Plant Immunity

Zhu Han; Dianguang Xiong; Haoyu Wu; et al. Plant Cell & Environment 2025. doi:10.1111/pce.70289

Other claims from this paper (12)

Observation Deletion of CcCAP2 affected C. chrysosperma vegetative growth.
Observation Deletion of CcCAP3 affected C. chrysosperma vegetative growth.
Association CcCAP2 contributed to C. chrysosperma virulence during interaction with Populus euramericana.
Observation CcCAP3 was predicted to be GPI-anchored.
Intervention effect Ectopic CcCAP2 expression in Nicotiana benthamiana promoted Botrytis cinerea infection.
Intervention effect Ectopic CcCAP2 expression in Nicotiana benthamiana inhibited immune-related gene expression.
Observation A poplar library screen gave the highest number of hits with RPB11.
Association CcCAP1 and CcCAP2 interacted with RPB11 in validation assays.
Intervention effect Silencing RPB11 caused a dwarf phenotype in the host plant.
Intervention effect Silencing RPB11 reduced fungal colonisation of the host plant.
Intervention effect Silencing RPB11 highly induced PR1 gene expression.
Mechanism The authors infer that CcCAP1 and CcCAP2 target plant RPB11 to suppress host immunity and facilitate infection.

Observationobservedoriginal resultmeasured

Claim · model-written summary

C. populina was identified as a known species.

Taxon: C. populinaCytospora populinae0
Outcome: known speciese0

Verbatim

e0
“revealed two new species ( Cytospora myricicola sp. nov. and C. sibiraeicola sp. nov. ) and a known species ( C. populina )”
✓ located verbatim in the source · abstract, characters 346–469

Title

Morphology and phylogeny of Cytospora (Cytosporaceae, Diaporthales) species associated with plant cankers in Tibet, China

Jiangrong Li; Jieting Li; Ning Jiang MycoKeys 2024. doi:10.3897/mycokeys.104.113567

Other claims from this paper (6)

Observation Cytospora canker symptoms were observed on Myricaria paniculate.
Observation Cytospora canker symptoms were observed on Prunus cerasifera.
Observation Cytospora canker symptoms were observed on Sibiraea angustata.
Observation Cytospora myricicola was described as a new species.
Observation C. sibiraeicola was described as a new species.
Observation Cytospora populina was newly found on Prunus cerasifera in Tibet.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Most pyrazole carboxamide thiazole derivatives showed good antifungal activity against Valsa mali.

Taxon: Valsa maliCytospora malie1
Treatment: 3i, 5i, 6i, 7i, 9i, 12i, 16i, 19i, and 23ie1
Outcome: antifungal activities against Valsa malie1

Not reportedComparatorDirection

Verbatim

e1
“most compounds ( 3i, 5i, 6i, 7i, 9i, 12i, 16i, 19i, and 23i ) exhibited good antifungal activities against Valsa mali”
✓ located verbatim in the source · abstract, characters 370–487

Title

Design, Synthesis, and Evaluation of Antifungal Bioactivity of Novel Pyrazole Carboxamide Thiazole Derivatives as SDH Inhibitors

Meng Li; Weiwei Wang; Xiang Cheng; et al. Journal of Agricultural and Food Chemistry 2023. doi:10.1021/acs.jafc.3c02671

Other claims from this paper (8)

Intervention effect Compound 6i had an EC50 of 1.77 against Valsa mali, better than the control drug boscalid.
Intervention effect Compound 19i had an EC50 of 1.97 mg/L against Valsa mali, better than the control drug boscalid.
Intervention effect Compound 23i had excellent inhibitory activity against Rhizoctonia solani, with an EC50 of 3.79 mg/L.
Intervention effect Compound 6i at 40 mg/L had a satisfactory in vivo protective effect against Valsa mali.
Intervention effect Compound 6i significantly damaged the surface morphology of Valsa mali.
Association Docking indicates compound 6i interacts with succinate dehydrogenase through hydrogen bonding and sigma-pi interaction.
Association The binding mode of compound 6i is similar to that of boscalid in succinate dehydrogenase.
Mechanism An enzyme activity experiment verified the action mode of compound 6i.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Compound 6i had an EC50 of 1.77 against Valsa mali, better than the control drug boscalid.

Taxon: Valsa maliCytospora malie2
Treatment: 6ie2
Outcome: EC 50 valuese2
Direction: bettere2
Value: 1.77e2
Qualifier: EC 50 = 9.19 mg/Le2
Comparator: control drug boscalide2

Verbatim

e2
“compounds 6i and 19i exhibited better antifungal activities against Valsa mali with EC 50 values of 1.77 and 1.97 mg/L, respectively, than the control drug boscalid (EC 50 = 9.19 mg/L)”
✓ located verbatim in the source · abstract, characters 505–689

Title

Design, Synthesis, and Evaluation of Antifungal Bioactivity of Novel Pyrazole Carboxamide Thiazole Derivatives as SDH Inhibitors

Meng Li; Weiwei Wang; Xiang Cheng; et al. Journal of Agricultural and Food Chemistry 2023. doi:10.1021/acs.jafc.3c02671

Other claims from this paper (8)

Intervention effect Most pyrazole carboxamide thiazole derivatives showed good antifungal activity against Valsa mali.
Intervention effect Compound 19i had an EC50 of 1.97 mg/L against Valsa mali, better than the control drug boscalid.
Intervention effect Compound 23i had excellent inhibitory activity against Rhizoctonia solani, with an EC50 of 3.79 mg/L.
Intervention effect Compound 6i at 40 mg/L had a satisfactory in vivo protective effect against Valsa mali.
Intervention effect Compound 6i significantly damaged the surface morphology of Valsa mali.
Association Docking indicates compound 6i interacts with succinate dehydrogenase through hydrogen bonding and sigma-pi interaction.
Association The binding mode of compound 6i is similar to that of boscalid in succinate dehydrogenase.
Mechanism An enzyme activity experiment verified the action mode of compound 6i.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Compound 19i had an EC50 of 1.97 mg/L against Valsa mali, better than the control drug boscalid.

Taxon: Valsa maliCytospora malie2
Treatment: 19ie2
Outcome: EC 50 valuese2
Direction: bettere2
Value: 1.97 mg/Le2
Qualifier: EC 50 = 9.19 mg/Le2
Comparator: control drug boscalide2

Verbatim

e2
“compounds 6i and 19i exhibited better antifungal activities against Valsa mali with EC 50 values of 1.77 and 1.97 mg/L, respectively, than the control drug boscalid (EC 50 = 9.19 mg/L)”
✓ located verbatim in the source · abstract, characters 505–689

Title

Design, Synthesis, and Evaluation of Antifungal Bioactivity of Novel Pyrazole Carboxamide Thiazole Derivatives as SDH Inhibitors

Meng Li; Weiwei Wang; Xiang Cheng; et al. Journal of Agricultural and Food Chemistry 2023. doi:10.1021/acs.jafc.3c02671

Other claims from this paper (8)

Intervention effect Most pyrazole carboxamide thiazole derivatives showed good antifungal activity against Valsa mali.
Intervention effect Compound 6i had an EC50 of 1.77 against Valsa mali, better than the control drug boscalid.
Intervention effect Compound 23i had excellent inhibitory activity against Rhizoctonia solani, with an EC50 of 3.79 mg/L.
Intervention effect Compound 6i at 40 mg/L had a satisfactory in vivo protective effect against Valsa mali.
Intervention effect Compound 6i significantly damaged the surface morphology of Valsa mali.
Association Docking indicates compound 6i interacts with succinate dehydrogenase through hydrogen bonding and sigma-pi interaction.
Association The binding mode of compound 6i is similar to that of boscalid in succinate dehydrogenase.
Mechanism An enzyme activity experiment verified the action mode of compound 6i.

Cytosporaceae 40 claims

40 claims