Claim · model-written summary
The authors suggest that bHLH transcription factors play conserved roles in modulating carbohydrate and lipid metabolism in fungi.
Verbatim
e0“bHLH transcription factors play conserved roles in modulating carbohydrate and lipid metabolism in fungi”
Title
Huijuan Cao; Hao Gong; Xiaohong Huang; et al. Molecular Plant Pathology 2026. doi:10.1111/mpp.70267
Other claims from this paper (8)
- Mechanism The bHLH transcription factor UvBhlh6 of U. virens plays a critical role during infection of rice.
- Observation UvBhlh6 physically interacts with UvBhlh1, UvBhlh4 and UvBhlh7 and also forms homodimers.
- Observation UvBhlh1 was also essential for full virulence of U. virens.
- Observation UvBhlh1 and UvBhlh6 form a heterodimer.
- Mechanism UvBhlh1 mediates the nuclear localisation of UvBhlh6, enabling their cooperative regulation of downstream target genes.
- Intervention effect ΔUvbhlh1 and ΔUvbhlh6 mutants showed reduced tolerance to H2O2-induced oxidative stress.
- Intervention effect ΔUvbhlh6 showed severely impaired growth under osmotic stress, with inhibition rates exceeding 90% on sorbitol or NaCl media.
- Observation Affinity capture and mass spectrometry identified UvBhlh6-interacting proteins including UvGal10, UvIdh1 and Pot1.