Coriariaceae 229 claims

family · order Cucurbitales · 9 taxa · NCBI Taxonomy ↗

9 entries

Coriaria nepalensisalso C.nepalensis102 claims · 25 papers Coriaria japonica43 claims · 15 papers Coriaria myrtifolia35 claims · 9 papers Coriaria28 claims · 13 papers Coriaria arborea13 claims · 4 papers Coriaria intermedia3 claims · 1 paper Coriariaceae3 claims · 1 paper Coriaria papuana1 claim · 1 paper Coriaria ruscifolia1 claim · 1 paper

229 claims

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Observationobservedoriginal resultmeasured

Claim · model-written summary

Eight undescribed coumarins were isolated from Coriaria nepalensis.

Taxon: Coriaria nepalensisCoriaria nepalensise0
Outcome: eight undescribed coumarins ( 1 – 8 )e0

Verbatim

e0
“eight undescribed coumarins ( 1 – 8 ), along with six reported coumarins ( 9 – 14 ), were obtained from Coriaria nepalensis”
✓ located verbatim in the source · abstract, characters 35–158

Title

Isolating Antipathogenic Fungal Coumarins from Coriaria nepalensis and Determining Their Primary Mechanism In Vitro

Jun-you Jian; Yi-min Fan; Jun Jin; et al. Journal of Agricultural and Food Chemistry 2024. doi:10.1021/acs.jafc.3c08573

Other claims from this paper (9)

Observation Six reported coumarins were isolated from Coriaria nepalensis.
Observation Compound 9 had broad spectrum antifungal activity against all tested fungi in vitro.
Observation Compound 9 significantly inhibited Phytophthora nicotianae with an EC 50 of 3.00 μg/mL.
Intervention effect Compound 9 had greater curative effects against tobacco black shank than osthol.
Intervention effect Compound 9 had greater protective effects against tobacco black shank than osthol.
Intervention effect Each of derivatives 17b, 17j and 17k had better effects on Sclerotinia sclerotiorum than compound 9.
Observation Compound 9 increased membrane permeability in P. nicotianae mycelia.
Observation Compound 9 damaged P. nicotianae cell morphology and ultrastructure.
Observation Compound 9 reduced exopolysaccharide content of P. nicotianae mycelia.

Observationobservedoriginal resultmeasured

Claim · model-written summary

Six reported coumarins were isolated from Coriaria nepalensis.

Taxon: Coriaria nepalensisCoriaria nepalensise0
Outcome: six reported coumarins ( 9 – 14 )e0

Verbatim

e0
“six reported coumarins ( 9 – 14 ), were obtained from Coriaria nepalensis”
✓ located verbatim in the source · abstract, characters 85–158

Title

Isolating Antipathogenic Fungal Coumarins from Coriaria nepalensis and Determining Their Primary Mechanism In Vitro

Jun-you Jian; Yi-min Fan; Jun Jin; et al. Journal of Agricultural and Food Chemistry 2024. doi:10.1021/acs.jafc.3c08573

Other claims from this paper (9)

Observation Eight undescribed coumarins were isolated from Coriaria nepalensis.
Observation Compound 9 had broad spectrum antifungal activity against all tested fungi in vitro.
Observation Compound 9 significantly inhibited Phytophthora nicotianae with an EC 50 of 3.00 μg/mL.
Intervention effect Compound 9 had greater curative effects against tobacco black shank than osthol.
Intervention effect Compound 9 had greater protective effects against tobacco black shank than osthol.
Intervention effect Each of derivatives 17b, 17j and 17k had better effects on Sclerotinia sclerotiorum than compound 9.
Observation Compound 9 increased membrane permeability in P. nicotianae mycelia.
Observation Compound 9 damaged P. nicotianae cell morphology and ultrastructure.
Observation Compound 9 reduced exopolysaccharide content of P. nicotianae mycelia.

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Compound 9 had broad spectrum antifungal activity against all tested fungi in vitro.

Taxon: Coriaria nepalensisCoriaria nepalensist0
Outcome: broad spectrum antifungal activities against all tested fungie0
Setting: in vitroe0

Verbatim

e0
“compound 9 exhibited broad spectrum antifungal activities against all tested fungi in vitro”
✓ located verbatim in the source · abstract, characters 306–397

t0
“Coriaria nepalensis”
✓ located verbatim in the source · title, characters 47–66

Title

Isolating Antipathogenic Fungal Coumarins from Coriaria nepalensis and Determining Their Primary Mechanism In Vitro

Jun-you Jian; Yi-min Fan; Jun Jin; et al. Journal of Agricultural and Food Chemistry 2024. doi:10.1021/acs.jafc.3c08573

Other claims from this paper (9)

Observation Eight undescribed coumarins were isolated from Coriaria nepalensis.
Observation Six reported coumarins were isolated from Coriaria nepalensis.
Observation Compound 9 significantly inhibited Phytophthora nicotianae with an EC 50 of 3.00 μg/mL.
Intervention effect Compound 9 had greater curative effects against tobacco black shank than osthol.
Intervention effect Compound 9 had greater protective effects against tobacco black shank than osthol.
Intervention effect Each of derivatives 17b, 17j and 17k had better effects on Sclerotinia sclerotiorum than compound 9.
Observation Compound 9 increased membrane permeability in P. nicotianae mycelia.
Observation Compound 9 damaged P. nicotianae cell morphology and ultrastructure.
Observation Compound 9 reduced exopolysaccharide content of P. nicotianae mycelia.

Observationobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

Compound 9 significantly inhibited Phytophthora nicotianae with an EC 50 of 3.00 μg/mL.

Taxon: Coriaria nepalensisCoriaria nepalensist0
Interactor: Phytophthora nicotianaePhytophthora nicotianaee0pathogen
Outcome: inhibitory effect on Phytophthora nicotianaee0
Value: 3.00 μg/mLe0

Verbatim

e0
“a significant inhibitory effect on Phytophthora nicotianae with an EC 50 value of 3.00 μg/mL”
✓ located verbatim in the source · abstract, characters 402–494

t0
“Coriaria nepalensis”
✓ located verbatim in the source · title, characters 47–66

Title

Isolating Antipathogenic Fungal Coumarins from Coriaria nepalensis and Determining Their Primary Mechanism In Vitro

Jun-you Jian; Yi-min Fan; Jun Jin; et al. Journal of Agricultural and Food Chemistry 2024. doi:10.1021/acs.jafc.3c08573

Other claims from this paper (9)

Observation Eight undescribed coumarins were isolated from Coriaria nepalensis.
Observation Six reported coumarins were isolated from Coriaria nepalensis.
Observation Compound 9 had broad spectrum antifungal activity against all tested fungi in vitro.
Intervention effect Compound 9 had greater curative effects against tobacco black shank than osthol.
Intervention effect Compound 9 had greater protective effects against tobacco black shank than osthol.
Intervention effect Each of derivatives 17b, 17j and 17k had better effects on Sclerotinia sclerotiorum than compound 9.
Observation Compound 9 increased membrane permeability in P. nicotianae mycelia.
Observation Compound 9 damaged P. nicotianae cell morphology and ultrastructure.
Observation Compound 9 reduced exopolysaccharide content of P. nicotianae mycelia.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Each of derivatives 17b, 17j and 17k had better effects on Sclerotinia sclerotiorum than compound 9.

Taxon: Coriaria nepalensisCoriaria nepalensist0
Treatment: 17b, 17j, and 17ke0
Interactor: Sclerotinia sclerotiorumSclerotinia sclerotiorume0pathogen
Outcome: effects on Sclerotinia sclerotiorume0
Direction: bettere0
Comparator: lead compound 9e0

Verbatim

e0
“novel derivatives ( 17b, 17j, and 17k ) exhibited better effects on Sclerotinia sclerotiorum than did lead compound 9”
✓ located verbatim in the source · abstract, characters 714–831

t0
“Coriaria nepalensis”
✓ located verbatim in the source · title, characters 47–66

Title

Isolating Antipathogenic Fungal Coumarins from Coriaria nepalensis and Determining Their Primary Mechanism In Vitro

Jun-you Jian; Yi-min Fan; Jun Jin; et al. Journal of Agricultural and Food Chemistry 2024. doi:10.1021/acs.jafc.3c08573

Other claims from this paper (9)

Observation Eight undescribed coumarins were isolated from Coriaria nepalensis.
Observation Six reported coumarins were isolated from Coriaria nepalensis.
Observation Compound 9 had broad spectrum antifungal activity against all tested fungi in vitro.
Observation Compound 9 significantly inhibited Phytophthora nicotianae with an EC 50 of 3.00 μg/mL.
Intervention effect Compound 9 had greater curative effects against tobacco black shank than osthol.
Intervention effect Compound 9 had greater protective effects against tobacco black shank than osthol.
Observation Compound 9 increased membrane permeability in P. nicotianae mycelia.
Observation Compound 9 damaged P. nicotianae cell morphology and ultrastructure.
Observation Compound 9 reduced exopolysaccharide content of P. nicotianae mycelia.

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Compound 9 increased membrane permeability in P. nicotianae mycelia.

Taxon: Coriaria nepalensisCoriaria nepalensist0
Interactor: P. nicotianaePhytophthora nicotianaee0pathogen
Outcome: cell membrane permeabilitye0
Direction: enhancee0

Verbatim

e0
“9 could enhance cell membrane permeability, destroy the morphology and ultrastructure of cells, and reduce the exopolysaccharide content of P. nicotianae mycelia”
✓ located verbatim in the source · abstract, characters 887–1048

t0
“Coriaria nepalensis”
✓ located verbatim in the source · title, characters 47–66

Title

Isolating Antipathogenic Fungal Coumarins from Coriaria nepalensis and Determining Their Primary Mechanism In Vitro

Jun-you Jian; Yi-min Fan; Jun Jin; et al. Journal of Agricultural and Food Chemistry 2024. doi:10.1021/acs.jafc.3c08573

Other claims from this paper (9)

Observation Eight undescribed coumarins were isolated from Coriaria nepalensis.
Observation Six reported coumarins were isolated from Coriaria nepalensis.
Observation Compound 9 had broad spectrum antifungal activity against all tested fungi in vitro.
Observation Compound 9 significantly inhibited Phytophthora nicotianae with an EC 50 of 3.00 μg/mL.
Intervention effect Compound 9 had greater curative effects against tobacco black shank than osthol.
Intervention effect Compound 9 had greater protective effects against tobacco black shank than osthol.
Intervention effect Each of derivatives 17b, 17j and 17k had better effects on Sclerotinia sclerotiorum than compound 9.
Observation Compound 9 damaged P. nicotianae cell morphology and ultrastructure.
Observation Compound 9 reduced exopolysaccharide content of P. nicotianae mycelia.

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Compound 9 damaged P. nicotianae cell morphology and ultrastructure.

Taxon: Coriaria nepalensisCoriaria nepalensist0
Interactor: P. nicotianaePhytophthora nicotianaee0pathogen
Outcome: morphology and ultrastructure of cellse0
Direction: destroye0

Verbatim

e0
“9 could enhance cell membrane permeability, destroy the morphology and ultrastructure of cells, and reduce the exopolysaccharide content of P. nicotianae mycelia”
✓ located verbatim in the source · abstract, characters 887–1048

t0
“Coriaria nepalensis”
✓ located verbatim in the source · title, characters 47–66

Title

Isolating Antipathogenic Fungal Coumarins from Coriaria nepalensis and Determining Their Primary Mechanism In Vitro

Jun-you Jian; Yi-min Fan; Jun Jin; et al. Journal of Agricultural and Food Chemistry 2024. doi:10.1021/acs.jafc.3c08573

Other claims from this paper (9)

Observation Eight undescribed coumarins were isolated from Coriaria nepalensis.
Observation Six reported coumarins were isolated from Coriaria nepalensis.
Observation Compound 9 had broad spectrum antifungal activity against all tested fungi in vitro.
Observation Compound 9 significantly inhibited Phytophthora nicotianae with an EC 50 of 3.00 μg/mL.
Intervention effect Compound 9 had greater curative effects against tobacco black shank than osthol.
Intervention effect Compound 9 had greater protective effects against tobacco black shank than osthol.
Intervention effect Each of derivatives 17b, 17j and 17k had better effects on Sclerotinia sclerotiorum than compound 9.
Observation Compound 9 increased membrane permeability in P. nicotianae mycelia.
Observation Compound 9 reduced exopolysaccharide content of P. nicotianae mycelia.

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Compound 9 reduced exopolysaccharide content of P. nicotianae mycelia.

Taxon: Coriaria nepalensisCoriaria nepalensist0
Interactor: P. nicotianaePhytophthora nicotianaee0pathogen
Outcome: exopolysaccharide content of P. nicotianae myceliae0
Direction: reducee0

Verbatim

e0
“9 could enhance cell membrane permeability, destroy the morphology and ultrastructure of cells, and reduce the exopolysaccharide content of P. nicotianae mycelia”
✓ located verbatim in the source · abstract, characters 887–1048

t0
“Coriaria nepalensis”
✓ located verbatim in the source · title, characters 47–66

Title

Isolating Antipathogenic Fungal Coumarins from Coriaria nepalensis and Determining Their Primary Mechanism In Vitro

Jun-you Jian; Yi-min Fan; Jun Jin; et al. Journal of Agricultural and Food Chemistry 2024. doi:10.1021/acs.jafc.3c08573

Other claims from this paper (9)

Observation Eight undescribed coumarins were isolated from Coriaria nepalensis.
Observation Six reported coumarins were isolated from Coriaria nepalensis.
Observation Compound 9 had broad spectrum antifungal activity against all tested fungi in vitro.
Observation Compound 9 significantly inhibited Phytophthora nicotianae with an EC 50 of 3.00 μg/mL.
Intervention effect Compound 9 had greater curative effects against tobacco black shank than osthol.
Intervention effect Compound 9 had greater protective effects against tobacco black shank than osthol.
Intervention effect Each of derivatives 17b, 17j and 17k had better effects on Sclerotinia sclerotiorum than compound 9.
Observation Compound 9 increased membrane permeability in P. nicotianae mycelia.
Observation Compound 9 damaged P. nicotianae cell morphology and ultrastructure.

Observationobservedoriginal resultnegativemeasured

Claim · model-written summary

The four isolates did not form root nodules on C. nepalensis.

Taxon: C. nepalensisCoriaria nepalensise0
Interactor: Theye0symbiont
Outcome: do not form root nodules on C. nepalensise0

Not reportedDirection

Verbatim

e0
“They do not form root nodules on C. nepalensis nor on Alnus glutinosa although they deformed root hairs of Alnus .”
✓ located verbatim in the source · abstract, characters 114–228

Title

Frankia nepalensis sp. nov., a non-infective non-nitrogen-fixing isolate from root nodules of Coriaria nepalensis Wall

Imen Nouioui; Meina Neumann-Schaal; Petar Pujic; et al. INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2023. doi:10.1099/ijsem.0.006199

Other claims from this paper (9)

Observation The isolates did not form root nodules on Alnus glutinosa.
Observation The isolates deformed Alnus root hairs.
Observation The isolates had bright red colonies, hyphae and sporangia, but lacked nitrogen-fixing vesicles and in vitro fixation.
Observation Comparative 16S rRNA analysis found CN4 T closest to Frankia saprophytica CN 3 T.
Observation Multilocus phylogeny assigned CN4 T to cluster 4 non-nodulating species.
Observation CN4 T and named Frankia species were below species-demarcation thresholds for dDDH and ANI.
Observation The four isolates grouped as one species by dDDH and ANI.
Observation CN4 T has a 10.76 Mb genome.
Observation The isolates were assigned to the proposed novel species Frankia nepalensis.

Observationobservedoriginal resultmeasured

Claim · model-written summary

The isolates had bright red colonies, hyphae and sporangia, but lacked nitrogen-fixing vesicles and in vitro fixation.

Taxon: Coriaria nepalensisCoriaria nepalensist0
Outcome: no N 2 -fixing vesicles and do not fix nitrogen in vitroe0

Verbatim

e0
“The colonies are bright red-pigmented, the strains form hyphae and sporangia but no N 2 -fixing vesicles and do not fix nitrogen in vitro .”
✓ located verbatim in the source · abstract, characters 229–368

t0
“Coriaria nepalensis”
✓ located verbatim in the source · title, characters 94–113

Title

Frankia nepalensis sp. nov., a non-infective non-nitrogen-fixing isolate from root nodules of Coriaria nepalensis Wall

Imen Nouioui; Meina Neumann-Schaal; Petar Pujic; et al. INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2023. doi:10.1099/ijsem.0.006199

Other claims from this paper (9)

Observation The four isolates did not form root nodules on C. nepalensis.
Observation The isolates did not form root nodules on Alnus glutinosa.
Observation The isolates deformed Alnus root hairs.
Observation Comparative 16S rRNA analysis found CN4 T closest to Frankia saprophytica CN 3 T.
Observation Multilocus phylogeny assigned CN4 T to cluster 4 non-nodulating species.
Observation CN4 T and named Frankia species were below species-demarcation thresholds for dDDH and ANI.
Observation The four isolates grouped as one species by dDDH and ANI.
Observation CN4 T has a 10.76 Mb genome.
Observation The isolates were assigned to the proposed novel species Frankia nepalensis.