Astragalus aduncus 12 claims

species · family Fabaceae · green plant · NCBI Taxonomy ↗

Also written in claims: A . aduncus — NCBI synonyms: Astragalus bingoellensis

3 spellings

12 claims

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Observationobservedoriginal resultmeasured

Claim · model-written summary

The 70% ethanol extract had the strongest antioxidant properties.

Taxon: Astragalus aduncusAstragalus aduncust0
Material: 70% ethanol extracte0
Outcome: antioxidant propertiese0
Direction: strongeste0

Verbatim

e0
“the 70% ethanol extract demonstrated the strongest antioxidant properties”
✓ located verbatim in the source · abstract, characters 785–858

t0
“Astragalus aduncus”
✓ located verbatim in the source · title, characters 91–109

Title

Influence of extraction solvents on the chemical constituents and biological activities of Astragalus aduncus from Turkey flora: In vitro and in silico insights

Irina Lazarova; Nilofar; Giovanni Caprioli; et al. Archiv der Pharmazie 2024. doi:10.1002/ardp.202400257

Other claims from this paper (10)

Observation The 70% ethanol extract had the highest total phenolic constituents.
Observation Ethyl acetate extract inhibited BChE at 11.44 mg GALAE/g.
Observation Ethanol extract inhibited BChE at 8.51 mg GALAE/g.
Observation Ethanol extract inhibited AChE at 3.42 mg GALAE/g.
Observation Ethanol/water extract inhibited AChE at 3.17 mg GALAE/g.
Observation Ethanol/water extract showed tyrosinase inhibition of 66.25 mg kojic acid equivalent/g.
Observation Ethyl acetate extract had an HGC-27 cytotoxic IC50 of 36.76 µg/mL.
Observation Ethanol extract had an HT-29 cytotoxic IC50 of 30.79 µg/mL.
Observation Water extract had a DU-145 cytotoxic IC50 of 37.01 µg/mL.
Association Total flavonoid content correlated strongly with individual compounds in the ethanol extract.

Observationobservedoriginal resultmeasured

Claim · model-written summary

The 70% ethanol extract had the highest total phenolic constituents.

Taxon: Astragalus aduncusAstragalus aduncust0
Outcome: total phenolic constituentse0
Direction: richeste0

Verbatim

e0
“it was the richest source of total phenolic constituents”
✓ located verbatim in the source · abstract, characters 864–920

t0
“Astragalus aduncus”
✓ located verbatim in the source · title, characters 91–109

Title

Influence of extraction solvents on the chemical constituents and biological activities of Astragalus aduncus from Turkey flora: In vitro and in silico insights

Irina Lazarova; Nilofar; Giovanni Caprioli; et al. Archiv der Pharmazie 2024. doi:10.1002/ardp.202400257

Other claims from this paper (10)

Observation The 70% ethanol extract had the strongest antioxidant properties.
Observation Ethyl acetate extract inhibited BChE at 11.44 mg GALAE/g.
Observation Ethanol extract inhibited BChE at 8.51 mg GALAE/g.
Observation Ethanol extract inhibited AChE at 3.42 mg GALAE/g.
Observation Ethanol/water extract inhibited AChE at 3.17 mg GALAE/g.
Observation Ethanol/water extract showed tyrosinase inhibition of 66.25 mg kojic acid equivalent/g.
Observation Ethyl acetate extract had an HGC-27 cytotoxic IC50 of 36.76 µg/mL.
Observation Ethanol extract had an HT-29 cytotoxic IC50 of 30.79 µg/mL.
Observation Water extract had a DU-145 cytotoxic IC50 of 37.01 µg/mL.
Association Total flavonoid content correlated strongly with individual compounds in the ethanol extract.

Observationobservedoriginal resultmeasured

Claim · model-written summary

Ethyl acetate extract inhibited BChE at 11.44 mg GALAE/g.

Taxon: Astragalus aduncusAstragalus aduncust0
Material: ethyl acetate extracte0
Outcome: BChE inhibitore0
Direction: most potente0
Value: 11.44 mg galantamine equivalents [GALAE]/ge0

Verbatim

e0
“the ethyl acetate extract was the most potent BChE inhibitor (11.44 mg galantamine equivalents [GALAE]/g)”
✓ located verbatim in the source · abstract, characters 950–1055

t0
“Astragalus aduncus”
✓ located verbatim in the source · title, characters 91–109

Title

Influence of extraction solvents on the chemical constituents and biological activities of Astragalus aduncus from Turkey flora: In vitro and in silico insights

Irina Lazarova; Nilofar; Giovanni Caprioli; et al. Archiv der Pharmazie 2024. doi:10.1002/ardp.202400257

Other claims from this paper (10)

Observation The 70% ethanol extract had the strongest antioxidant properties.
Observation The 70% ethanol extract had the highest total phenolic constituents.
Observation Ethanol extract inhibited BChE at 8.51 mg GALAE/g.
Observation Ethanol extract inhibited AChE at 3.42 mg GALAE/g.
Observation Ethanol/water extract inhibited AChE at 3.17 mg GALAE/g.
Observation Ethanol/water extract showed tyrosinase inhibition of 66.25 mg kojic acid equivalent/g.
Observation Ethyl acetate extract had an HGC-27 cytotoxic IC50 of 36.76 µg/mL.
Observation Ethanol extract had an HT-29 cytotoxic IC50 of 30.79 µg/mL.
Observation Water extract had a DU-145 cytotoxic IC50 of 37.01 µg/mL.
Association Total flavonoid content correlated strongly with individual compounds in the ethanol extract.

Observationobservedoriginal resultmeasured

Claim · model-written summary

Ethanol extract inhibited BChE at 8.51 mg GALAE/g.

Taxon: Astragalus aduncusAstragalus aduncust0
Material: ethanol extracte0
Outcome: BChE inhibitore0
Value: 8.51 mg GALAE/ge0

Verbatim

e0
“the ethyl acetate extract was the most potent BChE inhibitor (11.44 mg galantamine equivalents [GALAE]/g) followed by the ethanol extract (8.51 mg GALAE/g)”
✓ located verbatim in the source · abstract, characters 950–1105

t0
“Astragalus aduncus”
✓ located verbatim in the source · title, characters 91–109

Title

Influence of extraction solvents on the chemical constituents and biological activities of Astragalus aduncus from Turkey flora: In vitro and in silico insights

Irina Lazarova; Nilofar; Giovanni Caprioli; et al. Archiv der Pharmazie 2024. doi:10.1002/ardp.202400257

Other claims from this paper (10)

Observation The 70% ethanol extract had the strongest antioxidant properties.
Observation The 70% ethanol extract had the highest total phenolic constituents.
Observation Ethyl acetate extract inhibited BChE at 11.44 mg GALAE/g.
Observation Ethanol extract inhibited AChE at 3.42 mg GALAE/g.
Observation Ethanol/water extract inhibited AChE at 3.17 mg GALAE/g.
Observation Ethanol/water extract showed tyrosinase inhibition of 66.25 mg kojic acid equivalent/g.
Observation Ethyl acetate extract had an HGC-27 cytotoxic IC50 of 36.76 µg/mL.
Observation Ethanol extract had an HT-29 cytotoxic IC50 of 30.79 µg/mL.
Observation Water extract had a DU-145 cytotoxic IC50 of 37.01 µg/mL.
Association Total flavonoid content correlated strongly with individual compounds in the ethanol extract.

Observationobservedoriginal resultmeasured

Claim · model-written summary

Ethanol extract inhibited AChE at 3.42 mg GALAE/g.

Taxon: Astragalus aduncusAstragalus aduncust0
Material: ethanol extracte0
Outcome: AChE inhibitore0
Direction: most promisinge0
Value: 3.42 mg GALAE/ge0

Verbatim

e0
“the ethanol extract was the most promising AChE inhibitor (3.42 mg GALAE/g)”
✓ located verbatim in the source · abstract, characters 1113–1188

t0
“Astragalus aduncus”
✓ located verbatim in the source · title, characters 91–109

Title

Influence of extraction solvents on the chemical constituents and biological activities of Astragalus aduncus from Turkey flora: In vitro and in silico insights

Irina Lazarova; Nilofar; Giovanni Caprioli; et al. Archiv der Pharmazie 2024. doi:10.1002/ardp.202400257

Other claims from this paper (10)

Observation The 70% ethanol extract had the strongest antioxidant properties.
Observation The 70% ethanol extract had the highest total phenolic constituents.
Observation Ethyl acetate extract inhibited BChE at 11.44 mg GALAE/g.
Observation Ethanol extract inhibited BChE at 8.51 mg GALAE/g.
Observation Ethanol/water extract inhibited AChE at 3.17 mg GALAE/g.
Observation Ethanol/water extract showed tyrosinase inhibition of 66.25 mg kojic acid equivalent/g.
Observation Ethyl acetate extract had an HGC-27 cytotoxic IC50 of 36.76 µg/mL.
Observation Ethanol extract had an HT-29 cytotoxic IC50 of 30.79 µg/mL.
Observation Water extract had a DU-145 cytotoxic IC50 of 37.01 µg/mL.
Association Total flavonoid content correlated strongly with individual compounds in the ethanol extract.

Observationobservedoriginal resultmeasured

Claim · model-written summary

Ethanol/water extract inhibited AChE at 3.17 mg GALAE/g.

Taxon: Astragalus aduncusAstragalus aduncust0
Material: ethanol/water extracte0
Outcome: AChE inhibitore0
Value: 3.17 mg GALAE/ge0

Verbatim

e0
“the ethanol extract was the most promising AChE inhibitor (3.42 mg GALAE/g) followed by the ethanol/water extract (3.17 mg GALAE/g)”
✓ located verbatim in the source · abstract, characters 1113–1244

t0
“Astragalus aduncus”
✓ located verbatim in the source · title, characters 91–109

Title

Influence of extraction solvents on the chemical constituents and biological activities of Astragalus aduncus from Turkey flora: In vitro and in silico insights

Irina Lazarova; Nilofar; Giovanni Caprioli; et al. Archiv der Pharmazie 2024. doi:10.1002/ardp.202400257

Other claims from this paper (10)

Observation The 70% ethanol extract had the strongest antioxidant properties.
Observation The 70% ethanol extract had the highest total phenolic constituents.
Observation Ethyl acetate extract inhibited BChE at 11.44 mg GALAE/g.
Observation Ethanol extract inhibited BChE at 8.51 mg GALAE/g.
Observation Ethanol extract inhibited AChE at 3.42 mg GALAE/g.
Observation Ethanol/water extract showed tyrosinase inhibition of 66.25 mg kojic acid equivalent/g.
Observation Ethyl acetate extract had an HGC-27 cytotoxic IC50 of 36.76 µg/mL.
Observation Ethanol extract had an HT-29 cytotoxic IC50 of 30.79 µg/mL.
Observation Water extract had a DU-145 cytotoxic IC50 of 37.01 µg/mL.
Association Total flavonoid content correlated strongly with individual compounds in the ethanol extract.

Observationobservedoriginal resultmeasured

Claim · model-written summary

Ethanol/water extract showed tyrosinase inhibition of 66.25 mg kojic acid equivalent/g.

Taxon: A . aduncusAstragalus aduncuse0
Material: ethanol/water extractse0
Organ / stage: aerial parte0
Outcome: tyrosinase inhibitory activitye0
Value: 66.25 mg kojic acid equivalent/ge0

Verbatim

e0
“Excellent tyrosinase inhibitory activity (66.25 mg kojic acid equivalent/g) was observed in ethanol/water extracts of the aerial part of A . aduncus”
✓ located verbatim in the source · abstract, characters 1246–1394

Title

Influence of extraction solvents on the chemical constituents and biological activities of Astragalus aduncus from Turkey flora: In vitro and in silico insights

Irina Lazarova; Nilofar; Giovanni Caprioli; et al. Archiv der Pharmazie 2024. doi:10.1002/ardp.202400257

Other claims from this paper (10)

Observation The 70% ethanol extract had the strongest antioxidant properties.
Observation The 70% ethanol extract had the highest total phenolic constituents.
Observation Ethyl acetate extract inhibited BChE at 11.44 mg GALAE/g.
Observation Ethanol extract inhibited BChE at 8.51 mg GALAE/g.
Observation Ethanol extract inhibited AChE at 3.42 mg GALAE/g.
Observation Ethanol/water extract inhibited AChE at 3.17 mg GALAE/g.
Observation Ethyl acetate extract had an HGC-27 cytotoxic IC50 of 36.76 µg/mL.
Observation Ethanol extract had an HT-29 cytotoxic IC50 of 30.79 µg/mL.
Observation Water extract had a DU-145 cytotoxic IC50 of 37.01 µg/mL.
Association Total flavonoid content correlated strongly with individual compounds in the ethanol extract.

Observationobservedoriginal resultmeasured

Claim · model-written summary

Ethyl acetate extract had an HGC-27 cytotoxic IC50 of 36.76 µg/mL.

Taxon: Astragalus aduncusAstragalus aduncust0
Material: ethyl acetate extracte0
Outcome: cytotoxic effectse0
Value: 36.76 µg/mLe0

Verbatim

e0
“the most cytotoxic effects were exhibited by the ethyl acetate extract against HGC‐27 cells (IC 50 : 36.76 µg/mL)”
✓ located verbatim in the source · abstract, characters 1423–1536

t0
“Astragalus aduncus”
✓ located verbatim in the source · title, characters 91–109

Title

Influence of extraction solvents on the chemical constituents and biological activities of Astragalus aduncus from Turkey flora: In vitro and in silico insights

Irina Lazarova; Nilofar; Giovanni Caprioli; et al. Archiv der Pharmazie 2024. doi:10.1002/ardp.202400257

Other claims from this paper (10)

Observation The 70% ethanol extract had the strongest antioxidant properties.
Observation The 70% ethanol extract had the highest total phenolic constituents.
Observation Ethyl acetate extract inhibited BChE at 11.44 mg GALAE/g.
Observation Ethanol extract inhibited BChE at 8.51 mg GALAE/g.
Observation Ethanol extract inhibited AChE at 3.42 mg GALAE/g.
Observation Ethanol/water extract inhibited AChE at 3.17 mg GALAE/g.
Observation Ethanol/water extract showed tyrosinase inhibition of 66.25 mg kojic acid equivalent/g.
Observation Ethanol extract had an HT-29 cytotoxic IC50 of 30.79 µg/mL.
Observation Water extract had a DU-145 cytotoxic IC50 of 37.01 µg/mL.
Association Total flavonoid content correlated strongly with individual compounds in the ethanol extract.

Observationobservedoriginal resultmeasured

Claim · model-written summary

Ethanol extract had an HT-29 cytotoxic IC50 of 30.79 µg/mL.

Taxon: Astragalus aduncusAstragalus aduncust0
Material: ethanol extracte0
Outcome: cytotoxic effectse0
Value: 30.79 µg/mLe0

Verbatim

e0
“the most cytotoxic effects were exhibited by the ethyl acetate extract against HGC‐27 cells (IC 50 : 36.76 µg/mL), the ethanol extract against HT‐29 cells (IC 50 : 30.79 µg/mL)”
✓ located verbatim in the source · abstract, characters 1423–1599

t0
“Astragalus aduncus”
✓ located verbatim in the source · title, characters 91–109

Title

Influence of extraction solvents on the chemical constituents and biological activities of Astragalus aduncus from Turkey flora: In vitro and in silico insights

Irina Lazarova; Nilofar; Giovanni Caprioli; et al. Archiv der Pharmazie 2024. doi:10.1002/ardp.202400257

Other claims from this paper (10)

Observation The 70% ethanol extract had the strongest antioxidant properties.
Observation The 70% ethanol extract had the highest total phenolic constituents.
Observation Ethyl acetate extract inhibited BChE at 11.44 mg GALAE/g.
Observation Ethanol extract inhibited BChE at 8.51 mg GALAE/g.
Observation Ethanol extract inhibited AChE at 3.42 mg GALAE/g.
Observation Ethanol/water extract inhibited AChE at 3.17 mg GALAE/g.
Observation Ethanol/water extract showed tyrosinase inhibition of 66.25 mg kojic acid equivalent/g.
Observation Ethyl acetate extract had an HGC-27 cytotoxic IC50 of 36.76 µg/mL.
Observation Water extract had a DU-145 cytotoxic IC50 of 37.01 µg/mL.
Association Total flavonoid content correlated strongly with individual compounds in the ethanol extract.

Observationobservedoriginal resultmeasured

Claim · model-written summary

Water extract had a DU-145 cytotoxic IC50 of 37.01 µg/mL.

Taxon: Astragalus aduncusAstragalus aduncust0
Material: water extracte0
Outcome: cytotoxic effectse0
Value: 37.01 µg/mLe0

Verbatim

e0
“the most cytotoxic effects were exhibited by the ethyl acetate extract against HGC‐27 cells (IC 50 : 36.76 µg/mL), the ethanol extract against HT‐29 cells (IC 50 : 30.79 µg/mL), and the water extract against DU‐145 cells (IC 50 : 37.01 µg/mL)”
✓ located verbatim in the source · abstract, characters 1423–1665

t0
“Astragalus aduncus”
✓ located verbatim in the source · title, characters 91–109

Title

Influence of extraction solvents on the chemical constituents and biological activities of Astragalus aduncus from Turkey flora: In vitro and in silico insights

Irina Lazarova; Nilofar; Giovanni Caprioli; et al. Archiv der Pharmazie 2024. doi:10.1002/ardp.202400257

Other claims from this paper (10)

Observation The 70% ethanol extract had the strongest antioxidant properties.
Observation The 70% ethanol extract had the highest total phenolic constituents.
Observation Ethyl acetate extract inhibited BChE at 11.44 mg GALAE/g.
Observation Ethanol extract inhibited BChE at 8.51 mg GALAE/g.
Observation Ethanol extract inhibited AChE at 3.42 mg GALAE/g.
Observation Ethanol/water extract inhibited AChE at 3.17 mg GALAE/g.
Observation Ethanol/water extract showed tyrosinase inhibition of 66.25 mg kojic acid equivalent/g.
Observation Ethyl acetate extract had an HGC-27 cytotoxic IC50 of 36.76 µg/mL.
Observation Ethanol extract had an HT-29 cytotoxic IC50 of 30.79 µg/mL.
Association Total flavonoid content correlated strongly with individual compounds in the ethanol extract.