By organism › Green plants › Hypericaceae › Hypericum triquetrifolium

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

H. triquetrifolium had the strongest acetylcholinesterase inhibition.

Taxon: H. triquetrifoliumHypericum triquetrifoliume0
Outcome: acetylcholinesterase inhibitione0
Direction: strongeste0

Verbatim

e0
“H. triquetrifolium showed the strongest acetylcholinesterase inhibition”
✓ located verbatim in the source · abstract, characters 868–939

Title

Integrated LC–HRMS and HPLC Profiling of Fourteen Anatolian Hypericum Extracts Reveals Distinct Chemometric and Bioactivity Patterns

Ömerül Faruk Tavlı; Alevcan Kaplan; Hasan Şahin; et al. Pharmaceuticals 2026. doi:10.3390/ph19020299

Other claims from this paper (8)

Observation Anatolian Hypericum extracts formed distinct chemotypes driven primarily by phenolic acids and flavonol glycosides.
Observation Hyperoside was a consistently abundant marker.
Association Phenolic-rich extracts had enhanced functional properties in multiple assays.
Observation H. triquetrifolium showed notable antioxidant capacity.
Observation Selected Hypericum taxa had comparatively high tyrosinase or α-glucosidase inhibition.
Observation Antimicrobial activity was limited to Gram-positive bacteria and Candida spp.
Association Hypericum chemotypes were associated with bioactivity patterns.
Method / resource LC–HRMS-guided chemotyping was useful for pharmacognostic assessments.

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

H. triquetrifolium showed notable antioxidant capacity.

Taxon: H. triquetrifoliumHypericum triquetrifoliume0
Outcome: antioxidant capacitye0
Direction: notablee0

Verbatim

e0
“H. triquetrifolium showed the strongest acetylcholinesterase inhibition and notable antioxidant capacity”
✓ located verbatim in the source · abstract, characters 868–972

Title

Integrated LC–HRMS and HPLC Profiling of Fourteen Anatolian Hypericum Extracts Reveals Distinct Chemometric and Bioactivity Patterns

Ömerül Faruk Tavlı; Alevcan Kaplan; Hasan Şahin; et al. Pharmaceuticals 2026. doi:10.3390/ph19020299

Other claims from this paper (8)

Observation Anatolian Hypericum extracts formed distinct chemotypes driven primarily by phenolic acids and flavonol glycosides.
Observation Hyperoside was a consistently abundant marker.
Association Phenolic-rich extracts had enhanced functional properties in multiple assays.
Observation H. triquetrifolium had the strongest acetylcholinesterase inhibition.
Observation Selected Hypericum taxa had comparatively high tyrosinase or α-glucosidase inhibition.
Observation Antimicrobial activity was limited to Gram-positive bacteria and Candida spp.
Association Hypericum chemotypes were associated with bioactivity patterns.
Method / resource LC–HRMS-guided chemotyping was useful for pharmacognostic assessments.

Observationobservedoriginal resultmeasured

Claim · model-written summary

Major essential oil constituents included 2-methyloctane, α-pinene, 3-methylnonane and caryophyllene.

Taxon: H. triquetrifoliumHypericum triquetrifoliume0
Outcome: octane, 2-methyle0
Value: 1.35%-25.18%e0

Verbatim

e0
“The major components of H. triquetrifolium collected from 21 different locations were generally determined to be octane, 2-methyl (1.35%-25.18%), α-pinene (1.32%-19.1%), nonane, 3-methyl (2.43%-24.59%) and caryophyllene (3.79%-30.78%)”
✓ located verbatim in the source · abstract, characters 671–905

Title

Detailed Chemical Investigation of the Essential Oil and Aroma Contents of 21 Hypericum triquetrifolium Turra Species Collected From Different Localities via a Chemometric Approach

Serkan Yigitkan; Mehmet Akdeniz; Ozge Tokul Olmez; et al. Biomedical Chromatography 2026. doi:10.1002/bmc.70391

Other claims from this paper (16)

Observation α-Pinene ranged from 1.32% to 19.1% among essential oils.
Observation 3-Methylnonane ranged from 2.43% to 24.59% among essential oils.
Observation Caryophyllene ranged from 3.79% to 30.78% among essential oils.
Observation Major aroma 2-methyloctane ranged from 14.22% to 44%.
Observation Major aroma nonane ranged from 6.37% to 18.29%.
Observation Major aroma 3-methylnonane ranged from 7.62% to 23.12%.
Observation Major aroma 2-methyldecane ranged from 3.46% to 22.74%.
Observation All essential oil samples had moderate antioxidant capacity.
Observation S-19 had AChE inhibition of 87.61 ± 0.63%.
Observation S-9 had AChE inhibition of 84.29 ± 1.51%.
Observation S-11 had AChE inhibition of 82.28 ± 0.53%.
Observation S-1, S-4 and S-6 exceeded galantamine in BChE inhibition.
Observation S-5 and S-13 showed greater tyrosinase inhibition than other samples.
Observation The volatile components formed three PCA groups.
Association Regional differences had no significant effect on the volatile samples.
Method / resource The first two PCA components explained 59.2% of variance.

Observationobservedoriginal resultsignificant (as stated)measured

Claim · model-written summary

Shoot fresh weight increased particularly in H. olympicum, H. perforatum and H. triquetrifolium.

Taxon: H. olympicum, H. perforatum, and H. triquetrifoliumHypericum perforatumHypericum olympicumHypericum triquetrifoliume1
Outcome: shoot fresh weighte0

Verbatim

t0
“Effects of Culture Period and Plant Growth Regulators on In Vitro Biomass Production and Phenolic Compounds in Seven Species of Hypericum”
✓ located verbatim in the source · title, characters 0–137

e0
“shoot fresh weight increasing significantly at 60 days”
✓ located verbatim in the source · abstract, characters 563–617

e1
“particularly in H. olympicum, H. perforatum, and H. triquetrifolium”
✓ located verbatim in the source · abstract, characters 619–686

Title

Effects of Culture Period and Plant Growth Regulators on In Vitro Biomass Production and Phenolic Compounds in Seven Species of Hypericum

Doina Clapa; Monica Hârţa; Ana Maria Radomir; et al. Plants 2025. doi:10.3390/plants14152437

Other claims from this paper (6)

Intervention effect MS medium with 0.2 mg/L BA was the most effective condition for promoting biomass across Hypericum species.
Intervention effect Shoot fresh weight increased significantly at 60 days of culture.
Observation HPLC-DAD-ESI-MS identified 13 phenolic compounds in the Hypericum shoots.
Association Phenolic profiles were species-specific and influenced by culture period.
Observation H. kalmianum accumulated the highest total phenolic content, 37.6 mg/g DW.
Observation H. olympicum was the top producer of hypericin and pseudohypericin.

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Methanol extracts of the two Hypericum species had high total phenolic content.

Taxon: H.scabrum and H. triquetrifoliumHypericum triquetrifoliumHypericum scabrume1
Outcome: total phenolic contente0
Direction: riche0

Verbatim

e0
“The results showed that the methanol extracts were rich in total phenolic content.”
✓ located verbatim in the source · abstract, characters 610–692

e1
“methanol extracts from H.scabrum and H. triquetrifolium species”
✓ located verbatim in the source · abstract, characters 271–334

Title

Chemical Composition, in Vitro Bioactivity Evaluation, in Silico Molecular Docking and ADMET Study of Hypericum scabrum and Hypericum triquetrifolium

Turgut Taşkın; Mizgin Ermanoğlu; Erkan Rayaman; et al. Brazilian Archives of Biology and Technology 2024. doi:10.1590/1678-4324-2024240063

Other claims from this paper (7)

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

The extracts showed potent anti-urease, anti-crystallization and antimicrobial activity.

Taxon: H.scabrum and H. triquetrifoliumHypericum triquetrifoliumHypericum scabrume1
Outcome: anti-urease, anti-crystallization and antimicrobial activitye0
Direction: potente0

Verbatim

e0
“The extracts showed potent anti-urease, anti-crystallization and antimicrobial activity.”
✓ located verbatim in the source · abstract, characters 693–781

e1
“H.scabrum and H. triquetrifolium species”
✓ located verbatim in the source · abstract, characters 294–334

Title

Chemical Composition, in Vitro Bioactivity Evaluation, in Silico Molecular Docking and ADMET Study of Hypericum scabrum and Hypericum triquetrifolium

Turgut Taşkın; Mizgin Ermanoğlu; Erkan Rayaman; et al. Brazilian Archives of Biology and Technology 2024. doi:10.1590/1678-4324-2024240063

Other claims from this paper (7)

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Methanol extracts showed no toxicity in the L-929 cell line.

Taxon: H.scabrum and H. triquetrifoliumHypericum triquetrifoliumHypericum scabrume1
Outcome: toxicity in the normal cell line (L-929)e0
Direction: didn’t showe0

Verbatim

e0
“Methanol extracts didn’t show toxicity in the normal cell line (L-929).”
✓ located verbatim in the source · abstract, characters 782–853

e1
“H.scabrum and H. triquetrifolium species”
✓ located verbatim in the source · abstract, characters 294–334

Title

Chemical Composition, in Vitro Bioactivity Evaluation, in Silico Molecular Docking and ADMET Study of Hypericum scabrum and Hypericum triquetrifolium

Turgut Taşkın; Mizgin Ermanoğlu; Erkan Rayaman; et al. Brazilian Archives of Biology and Technology 2024. doi:10.1590/1678-4324-2024240063

Other claims from this paper (7)

Observationobservedoriginal resultmeasured

Claim · model-written summary

The methanol extracts contained quantified isorhamnetin, rutin and chlorogenic acid.

Taxon: H.scabrum and H. triquetrifoliumHypericum triquetrifoliumHypericum scabrume1
Outcome: amounts of isorhamnetin, rutin, and chlorogenic acide0

Verbatim

e0
“quantitatively assess the amounts of isorhamnetin, rutin, and chlorogenic acid in methanol extracts from both plants”
✓ located verbatim in the source · abstract, characters 887–1003

e1
“H.scabrum and H. triquetrifolium species”
✓ located verbatim in the source · abstract, characters 294–334

Title

Chemical Composition, in Vitro Bioactivity Evaluation, in Silico Molecular Docking and ADMET Study of Hypericum scabrum and Hypericum triquetrifolium

Turgut Taşkın; Mizgin Ermanoğlu; Erkan Rayaman; et al. Brazilian Archives of Biology and Technology 2024. doi:10.1590/1678-4324-2024240063

Other claims from this paper (7)

Observationobservedoriginal resultsimulated

Claim · model-written summary

Chlorogenic acid docked to xanthine oxidase with a binding affinity of -10.3 kcal/mol.

Taxon: H.scabrum and H. triquetrifoliumHypericum triquetrifoliumHypericum scabrume1
Outcome: binding affinitye0
Value: -10.3 kcal/mole0

Verbatim

e0
“With a binding affinity of -10.3 kcal/mol, chlorogenic acid docks to the xanthine oxidase enzyme's active site.”
✓ located verbatim in the source · abstract, characters 1192–1303

e1
“H.scabrum and H. triquetrifolium species”
✓ located verbatim in the source · abstract, characters 294–334

Title

Chemical Composition, in Vitro Bioactivity Evaluation, in Silico Molecular Docking and ADMET Study of Hypericum scabrum and Hypericum triquetrifolium

Turgut Taşkın; Mizgin Ermanoğlu; Erkan Rayaman; et al. Brazilian Archives of Biology and Technology 2024. doi:10.1590/1678-4324-2024240063

Other claims from this paper (7)

Observationobservedoriginal resultsimulated

Claim · model-written summary

Rutin docked to myeloperoxidase with a binding affinity of -9,9 kcal/mol.

Taxon: H.scabrum and H. triquetrifoliumHypericum triquetrifoliumHypericum scabrume1
Outcome: binding affinitye0
Value: -9,9 kcal/mole0

Verbatim

e0
“Rutin binds to the myeloperoxidase enzyme's active site with a binding affinity of -9,9 kcal/mol.”
✓ located verbatim in the source · abstract, characters 1304–1401

e1
“H.scabrum and H. triquetrifolium species”
✓ located verbatim in the source · abstract, characters 294–334

Title

Chemical Composition, in Vitro Bioactivity Evaluation, in Silico Molecular Docking and ADMET Study of Hypericum scabrum and Hypericum triquetrifolium

Turgut Taşkın; Mizgin Ermanoğlu; Erkan Rayaman; et al. Brazilian Archives of Biology and Technology 2024. doi:10.1590/1678-4324-2024240063

Other claims from this paper (7)

Hypericum triquetrifolium 234 claims

234 claims