Intervention effectmodel-written summary

Transient expression of constitutively active SlMKK2DD and SlMKK4DD elevated defense gene expression in Nicotiana benthamiana

A claim from Tomato SlMKK2 and SlMKK4 contribute to disease resistance against Botrytis cinerea · 2014

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Transient expression of constitutively active SlMKK2DD and SlMKK4DD elevated defense gene expression in Nicotiana benthamiana

Taxon
Nicotiana benthamianaNicotiana benthamianae1
Treatment
transient expression of constitutively active phosphomimicking forms SlMKK2DD and SlMKK4DDe1
Gene
SlMKK2DD and SlMKK4DDe1
Outcome
expression of defense genese1
Direction
elevatede1

Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Nicotiana benthamiana
Nicotiana benthamiana · TaxonCharles Andres · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e1

“transient expression of constitutively active phosphomimicking forms SlMKK2DD and SlMKK4DD in leaves of Nicotiana benthamiana plants led to enhanced resistance to B. cinerea and elevated expression of defense genes”

✓ located verbatim in the source · abstract, characters 1115–1329

Title

Tomato SlMKK2 and SlMKK4 contribute to disease resistance against Botrytis cinerea

Xiaohui Li; Yafen Zhang; Lei Huang; et al. BMC Plant Biology 2014. doi:10.1186/1471-2229-14-166

Other claims from this paper (10)

Record rev-2b1e1a2ca529d4bc39c8c651b70694adb77ea5526c8f7f7c92ddf480a3f179fd · schema claims-v0.9 · position 10 in the model’s answer

transgenic · molecular: expression · Nicotiana benthamianaPositive and negative results

29 papers: 20 positive, 9 negative or no effect

19 papers in the same direction as this claim · 9 in the opposite direction

  1. positive
    Transient expression of ClMPK1, ClMPK4-2 and ClMPK7 upregulated defense genes.

    Characterization, expression patterns and functional analysis of the MAPK and MAPKK genes in watermelon (Citrullus lanatus) · 2015

    Same directionCites this paper

  2. negative
    TGBp3 expression induced the same host genes in N. benthamiana leaves.

    The Unfolded Protein Response Is Triggered by a Plant Viral Movement Protein     · 2011

    Opposite direction

  3. negative
    RipAL induced expression of JA-signaling marker genes in N. benthamiana leaves.

    Ralstonia solanacearum Type III Effector RipAL Targets Chloroplasts and Induces Jasmonic Acid Production to Suppress Salicylic Acid-Mediated Defense Responses in Plants · 2018

    Opposite direction

  4. no effect
    Expression of TMV ORF6 failed to suppress gene silencing in Nicotiana benthamiana.

    ORF6 of Tobacco mosaic virus is a determinant of viral pathogenicity in Nicotiana benthamiana · 2004

    Opposite direction

  5. negative
    Agrobacterium-mediated foreign protein expression shut down chloroplast gene expression.

    Molecular responses of agroinfiltrated Nicotiana benthamiana leaves expressing suppressor of silencing P19 and influenza virus‐like particles · 2023

    Opposite direction

  6. negative
    Transient FocRnt2 expression suppressed salicylic acid and jasmonic acid signaling marker genes.

    A ribonuclease T2 protein FocRnt2 contributes to the virulence of Fusarium oxysporum f. sp. cubense tropical race 4 · 2024

    Opposite direction

  7. negative
    Transient MiPDCD6 expression reduced PR1 and PR5 expression in Nicotiana benthamiana.

    MiPDCD6 effector suppresses host PAMP ‐triggered immunity to facilitate Meloidogyne incognita parasitism in tomato · 2022

    Opposite direction

  8. negative
    Transient LtCSEP1 expression inhibits flg22-induced PTI-associated gene expression.

    A Putative Effector LtCSEP1 from Lasiodiplodia theobromae Inhibits BAX-Triggered Cell Death and Suppresses Immunity Responses in Nicotiana benthamiana · 2022

    Opposite direction

20 papers more in this group

See all 29 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.