Claim · model-written summary
GgcDOPA6GT from Gomphrena globosa specifically mediates gomphrenin I formation.
- Taxon
- Gomphrena globosa
Gomphrena globosat0 - Gene
- GgcDOPA6GTe1
- Compound
- gomphrenin Ie1
- Outcome
- gomphrenin I formatione1
Verbatim
t0“gomphrenin I biosynthesis in Basella alba and Gomphrena globosa”
e1“GgcDOPA6GT specifically mediated gomphrenin I formation”
Title
Tomohiro Imamura; Ryouta Shigehisa; Akio Miyazato; et al. New Phytologist 2026. doi:10.1111/nph.71340
Other claims from this paper (5)
- Observation BacDOPA5/6GTs from Basella alba glucosylate cyclo-DOPA at both the 5-O and 6-O positions, producing betanin and gomphrenin I.
- Observation The Basella alba and Gomphrena globosa enzymes belong to distinct subclades within the cDOPA-GT family.
- Observation Mutational analysis shows essential roles for conserved histidine residues and an alpha-helical region next to the catalytic site.
- Observation Gomphrenin I is more thermally stable than betanin.
- Mechanism The higher thermal stability of gomphrenin I is likely due to an intramolecular hydrogen bond.
