Abstract
Plants under low-oxygen conditions adapt their metabolism by inducing the fermentative pathway, with ethanol as the predominant end product. Activities of pyruvate decarboxylase (PDC) and alcohol dehydrogenase (ADH) are required for this pathway. While a single gene encodes ADH in Arabidopsis, a family of four genes codes PDC. The availability of microarray data sets enabled the relative importance of the four PDC genes under low oxygen to be assessed, and revealed that, contrary to previous published evidence, not only PDC1 but also PDC2 plays a role under hypoxic conditions. We observed a high level of expression, both at transcript and protein levels of PDCs, even under aerobic conditions when ADH is almost absent. This suggests that PDC has a role under aerobic conditions, which is not coupled to fermentative metabolism. The expression of both PDC1 and PDC2 is strongly up-regulated under low oxygen. PDC1 is predominantly present in roots, while PDC2 appears to be leaf-specific. We showed that mutations in both PDC1 and PDC2 result in lower tolerance to submergence.
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Claims 8
Claim · model-written summary
Microarray data implicated PDC2 alongside PDC1 in hypoxic response.
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianat0 - Gene
- PDC2e0
- Outcome
- plays a role under hypoxic conditionse0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“not only PDC1 but also PDC2 plays a role under hypoxic conditions”
t0“Arabidopsis thaliana”
Claim · model-written summary
PDC expression was high at transcript and protein levels under aerobic conditions, while ADH was almost absent.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Gene
- PDCse0
- Outcome
- high level of expression, both at transcript and protein levelse0
- Qualifier
- under aerobic conditions when ADH is almost absente0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“We observed a high level of expression, both at transcript and protein levels of PDCs, even under aerobic conditions when ADH is almost absent.”
t0“Arabidopsis thaliana”
Claim · model-written summary
The authors infer an aerobic PDC role separate from fermentation.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Gene
- PDCe0
- Outcome
- role under aerobic conditionse0
- Qualifier
- not coupled to fermentative metabolisme0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“This suggests that PDC has a role under aerobic conditions, which is not coupled to fermentative metabolism.”
t0“Arabidopsis thaliana”
Claim · model-written summary
Low oxygen strongly upregulated PDC1 and PDC2 expression.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Treatment
- low oxygene0
- Gene
- PDC1 and PDC2e0
- Outcome
- expressione0
- Direction
- up-regulatede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The expression of both PDC1 and PDC2 is strongly up-regulated under low oxygen.”
t0“Arabidopsis thaliana”
Claim · model-written summary
PDC1 was predominantly in roots.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Organ / stage
- rootse0
- Gene
- PDC1e0
- Outcome
- predominantly present in rootse0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“PDC1 is predominantly present in roots, while PDC2 appears to be leaf-specific.”
t0“Arabidopsis thaliana”
Claim · model-written summary
PDC2 appeared leaf specific.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Gene
- PDC2e0
- Outcome
- leaf-specifice0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“PDC1 is predominantly present in roots, while PDC2 appears to be leaf-specific.”
t0“Arabidopsis thaliana”
Claim · model-written summary
PDC1 mutations reduced submergence tolerance.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Treatment
- mutationse0
- Gene
- PDC1e0
- Outcome
- tolerance to submergencee0
- Direction
- lowere0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“mutations in both PDC1 and PDC2 result in lower tolerance to submergence”
t0“Arabidopsis thaliana”
Claim · model-written summary
PDC2 mutations reduced submergence tolerance.
- Taxon
- Arabidopsis thalianaArabidopsis thalianat0
- Treatment
- mutationse0
- Gene
- PDC2e0
- Outcome
- tolerance to submergencee0
- Direction
- lowere0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“mutations in both PDC1 and PDC2 result in lower tolerance to submergence”
t0“Arabidopsis thaliana”
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