Aphelenchoididae 106 claims

family · order Rhabditida · 24 taxa · NCBI Taxonomy ↗

24 entries

106 claims

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Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Compound A1 was toxic to Bursaphelenchus xylophilus with an LC50 of 4.3 mg/L, outperforming the commercial nematicide tioxazafen.

Taxon: Bursaphelenchus xylophilusBursaphelenchus xylophiluse0
Treatment: Compound A1e0
Outcome: median lethal concentration ( LC 50 )e0
Direction: outperforminge0
Value: 4.3e0
Comparator: tioxazafene0

Verbatim

e0
“Compound A1 displayed remarkable toxicity against Bursaphelenchus xylophilus , Aphelenchoides besseyi , and Meloidogyne incognita with median lethal concentration ( LC 50 ) values of 4.3, 1.9, and 6.2 mg/L, respectively, outperforming the commercial nematicide tioxazafen”
✓ located verbatim in the source · abstract, characters 505–776

Title

Design, synthesis, nematicidal activity, and preliminary mechanism of thiazole derivatives through the scaffold hopping strategy

Zongnan Zhu; Siyu Lu; Xiuhai Gan; et al. Pest Management Science 2026. doi:10.1002/ps.70644

Other claims from this paper (10)

Intervention effect Compound A1 was toxic to Aphelenchoides besseyi with an LC50 of 1.9 mg/L, outperforming the commercial nematicide tioxazafen.
Intervention effect Compound A1 was toxic to Meloidogyne incognita with an LC50 of 6.2 mg/L, outperforming the commercial nematicide tioxazafen.
Intervention effect Compound A1 inhibited nematode egg hatching.
Intervention effect Compound A1 induced excessive accumulation of reactive oxygen species in nematodes.
Intervention effect Compound A1 caused vacuolization in nematode tissues.
Intervention effect In pot experiments, compound A1 reduced nematode invasion of tomato plants.
Intervention effect In pot experiments, compound A1 enhanced the root defense response of tomato plants.
Intervention effect Compound A1 significantly inhibited succinate dehydrogenase activity in Meloidogyne incognita.
Mechanism The authors suggest that interference with mitochondrial energy metabolism may contribute to the nematicidal effect of compound A1 in M. incognita.
Recommendation Thiazole-based compound A1 can serve as a lead compound from which new nematicides can be discovered through structural optimization.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Compound A1 was toxic to Aphelenchoides besseyi with an LC50 of 1.9 mg/L, outperforming the commercial nematicide tioxazafen.

Taxon: Aphelenchoides besseyiAphelenchoides besseyie0
Treatment: Compound A1e0
Outcome: median lethal concentration ( LC 50 )e0
Direction: outperforminge0
Value: 1.9e0
Comparator: tioxazafene0

Verbatim

e0
“Compound A1 displayed remarkable toxicity against Bursaphelenchus xylophilus , Aphelenchoides besseyi , and Meloidogyne incognita with median lethal concentration ( LC 50 ) values of 4.3, 1.9, and 6.2 mg/L, respectively, outperforming the commercial nematicide tioxazafen”
✓ located verbatim in the source · abstract, characters 505–776

Title

Design, synthesis, nematicidal activity, and preliminary mechanism of thiazole derivatives through the scaffold hopping strategy

Zongnan Zhu; Siyu Lu; Xiuhai Gan; et al. Pest Management Science 2026. doi:10.1002/ps.70644

Other claims from this paper (10)

Intervention effect Compound A1 was toxic to Bursaphelenchus xylophilus with an LC50 of 4.3 mg/L, outperforming the commercial nematicide tioxazafen.
Intervention effect Compound A1 was toxic to Meloidogyne incognita with an LC50 of 6.2 mg/L, outperforming the commercial nematicide tioxazafen.
Intervention effect Compound A1 inhibited nematode egg hatching.
Intervention effect Compound A1 induced excessive accumulation of reactive oxygen species in nematodes.
Intervention effect Compound A1 caused vacuolization in nematode tissues.
Intervention effect In pot experiments, compound A1 reduced nematode invasion of tomato plants.
Intervention effect In pot experiments, compound A1 enhanced the root defense response of tomato plants.
Intervention effect Compound A1 significantly inhibited succinate dehydrogenase activity in Meloidogyne incognita.
Mechanism The authors suggest that interference with mitochondrial energy metabolism may contribute to the nematicidal effect of compound A1 in M. incognita.
Recommendation Thiazole-based compound A1 can serve as a lead compound from which new nematicides can be discovered through structural optimization.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Both gold nanomaterials induced B. xylophilus immobilization in a concentration- and time-dependent manner in vitro.

Taxon: Bursaphelenchus xylophilusBursaphelenchus xylophilust0
Treatment: both nanomaterialse0
Outcome: nematode immobilizatione0
Direction: inducede0

Not reportedComparator

Verbatim

e0
“both nanomaterials induced nematode immobilization in a concentration- and time-dependent manner”
✓ located verbatim in the source · abstract, characters 867–963

t0
“Bursaphelenchus xylophilus”
✓ located verbatim in the source · title, characters 122–148

Title

Physicochemically distinct gold nanomaterials suppress pine wilt disease through divergent nematicidal mechanisms against Bursaphelenchus xylophilus

Nabi Noor Ul Ghani; Qiannan Liu; Jie Qi; et al. Plant Nano Biology 2026. doi:10.1016/j.plana.2026.100286

Other claims from this paper (12)

Intervention effect 0.5 mg/L His-AuNCs caused about 70% nematode immobility after 48 hours.
Intervention effect 0.5 mg/L PEI-AuNPs caused over 75% nematode immobility after 48 hours.
Intervention effect In feeding-based assays both gold nanomaterials suppressed nematode population expansion.
Observation Both nanoparticles were internalized by B. xylophilus and accumulated in internal tissues, particularly the anterior and intestinal regions.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L delayed symptom onset in pine seedlings.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L reduced disease severity in pine seedlings.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L preserved vascular integrity in pine seedlings.
Intervention effect His-AuNCs downregulated genes related to cuticle formation and metabolism in the nematode.
Intervention effect PEI-AuNPs induced a focused stress response in the nematode, primarily upregulating heat shock proteins.
Intervention effect Both gold nanomaterials showed minimal acute toxicity in zebrafish assays.
Method / resource Green synthesis of His-AuNCs yielded monodisperse particles of 1.36 ± 0.05 nm with a zeta potential of -19.2 ± 0.3 mV.
Method / resource PEI-AuNPs were uniform spherical particles with a hydrodynamic diameter of 11.18 ± 0.9 nm.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

0.5 mg/L His-AuNCs caused about 70% nematode immobility after 48 hours.

Taxon: Bursaphelenchus xylophilusBursaphelenchus xylophilust0
Treatment: 0.5 mg/L His-AuNCse1
Outcome: immobilitye1
Direction: causinge1
Value: ~70%e1

Not reportedComparator

Verbatim

e1
“0.5 mg/L His-AuNCs causing ~70% immobility”
✓ located verbatim in the source · abstract, characters 970–1012

t0
“Bursaphelenchus xylophilus”
✓ located verbatim in the source · title, characters 122–148

Title

Physicochemically distinct gold nanomaterials suppress pine wilt disease through divergent nematicidal mechanisms against Bursaphelenchus xylophilus

Nabi Noor Ul Ghani; Qiannan Liu; Jie Qi; et al. Plant Nano Biology 2026. doi:10.1016/j.plana.2026.100286

Other claims from this paper (12)

Intervention effect Both gold nanomaterials induced B. xylophilus immobilization in a concentration- and time-dependent manner in vitro.
Intervention effect 0.5 mg/L PEI-AuNPs caused over 75% nematode immobility after 48 hours.
Intervention effect In feeding-based assays both gold nanomaterials suppressed nematode population expansion.
Observation Both nanoparticles were internalized by B. xylophilus and accumulated in internal tissues, particularly the anterior and intestinal regions.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L delayed symptom onset in pine seedlings.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L reduced disease severity in pine seedlings.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L preserved vascular integrity in pine seedlings.
Intervention effect His-AuNCs downregulated genes related to cuticle formation and metabolism in the nematode.
Intervention effect PEI-AuNPs induced a focused stress response in the nematode, primarily upregulating heat shock proteins.
Intervention effect Both gold nanomaterials showed minimal acute toxicity in zebrafish assays.
Method / resource Green synthesis of His-AuNCs yielded monodisperse particles of 1.36 ± 0.05 nm with a zeta potential of -19.2 ± 0.3 mV.
Method / resource PEI-AuNPs were uniform spherical particles with a hydrodynamic diameter of 11.18 ± 0.9 nm.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

0.5 mg/L PEI-AuNPs caused over 75% nematode immobility after 48 hours.

Taxon: Bursaphelenchus xylophilusBursaphelenchus xylophilust0
Treatment: 0.5 mg/L PEI-AuNPse2
Outcome: immobilitye2
Direction: causinge2
Value: over 75%e2

Not reportedComparator

Verbatim

e2
“0.5 mg/L PEI-AuNPs causing over 75% immobility after 48 hours”
✓ located verbatim in the source · abstract, characters 1017–1078

t0
“Bursaphelenchus xylophilus”
✓ located verbatim in the source · title, characters 122–148

Title

Physicochemically distinct gold nanomaterials suppress pine wilt disease through divergent nematicidal mechanisms against Bursaphelenchus xylophilus

Nabi Noor Ul Ghani; Qiannan Liu; Jie Qi; et al. Plant Nano Biology 2026. doi:10.1016/j.plana.2026.100286

Other claims from this paper (12)

Intervention effect Both gold nanomaterials induced B. xylophilus immobilization in a concentration- and time-dependent manner in vitro.
Intervention effect 0.5 mg/L His-AuNCs caused about 70% nematode immobility after 48 hours.
Intervention effect In feeding-based assays both gold nanomaterials suppressed nematode population expansion.
Observation Both nanoparticles were internalized by B. xylophilus and accumulated in internal tissues, particularly the anterior and intestinal regions.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L delayed symptom onset in pine seedlings.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L reduced disease severity in pine seedlings.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L preserved vascular integrity in pine seedlings.
Intervention effect His-AuNCs downregulated genes related to cuticle formation and metabolism in the nematode.
Intervention effect PEI-AuNPs induced a focused stress response in the nematode, primarily upregulating heat shock proteins.
Intervention effect Both gold nanomaterials showed minimal acute toxicity in zebrafish assays.
Method / resource Green synthesis of His-AuNCs yielded monodisperse particles of 1.36 ± 0.05 nm with a zeta potential of -19.2 ± 0.3 mV.
Method / resource PEI-AuNPs were uniform spherical particles with a hydrodynamic diameter of 11.18 ± 0.9 nm.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

In feeding-based assays both gold nanomaterials suppressed nematode population expansion.

Taxon: Bursaphelenchus xylophilusBursaphelenchus xylophilust0
Treatment: both materialse3
Outcome: nematode population expansione3
Direction: suppressede3
Setting: feeding-based assayse3

Not reportedComparator

Verbatim

e3
“In feeding-based assays, both materials suppressed nematode population expansion”
✓ located verbatim in the source · abstract, characters 1080–1160

t0
“Bursaphelenchus xylophilus”
✓ located verbatim in the source · title, characters 122–148

Title

Physicochemically distinct gold nanomaterials suppress pine wilt disease through divergent nematicidal mechanisms against Bursaphelenchus xylophilus

Nabi Noor Ul Ghani; Qiannan Liu; Jie Qi; et al. Plant Nano Biology 2026. doi:10.1016/j.plana.2026.100286

Other claims from this paper (12)

Intervention effect Both gold nanomaterials induced B. xylophilus immobilization in a concentration- and time-dependent manner in vitro.
Intervention effect 0.5 mg/L His-AuNCs caused about 70% nematode immobility after 48 hours.
Intervention effect 0.5 mg/L PEI-AuNPs caused over 75% nematode immobility after 48 hours.
Observation Both nanoparticles were internalized by B. xylophilus and accumulated in internal tissues, particularly the anterior and intestinal regions.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L delayed symptom onset in pine seedlings.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L reduced disease severity in pine seedlings.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L preserved vascular integrity in pine seedlings.
Intervention effect His-AuNCs downregulated genes related to cuticle formation and metabolism in the nematode.
Intervention effect PEI-AuNPs induced a focused stress response in the nematode, primarily upregulating heat shock proteins.
Intervention effect Both gold nanomaterials showed minimal acute toxicity in zebrafish assays.
Method / resource Green synthesis of His-AuNCs yielded monodisperse particles of 1.36 ± 0.05 nm with a zeta potential of -19.2 ± 0.3 mV.
Method / resource PEI-AuNPs were uniform spherical particles with a hydrodynamic diameter of 11.18 ± 0.9 nm.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

His-AuNCs downregulated genes related to cuticle formation and metabolism in the nematode.

Taxon: Bursaphelenchus xylophilusBursaphelenchus xylophilust0
Treatment: His-AuNCse6
Outcome: genes related to cuticle formation and metabolisme6
Direction: downregulatede6

Not reportedComparator

Verbatim

e6
“His-AuNCs downregulated genes related to cuticle formation and metabolism”
✓ located verbatim in the source · abstract, characters 1574–1647

t0
“Bursaphelenchus xylophilus”
✓ located verbatim in the source · title, characters 122–148

Title

Physicochemically distinct gold nanomaterials suppress pine wilt disease through divergent nematicidal mechanisms against Bursaphelenchus xylophilus

Nabi Noor Ul Ghani; Qiannan Liu; Jie Qi; et al. Plant Nano Biology 2026. doi:10.1016/j.plana.2026.100286

Other claims from this paper (12)

Intervention effect Both gold nanomaterials induced B. xylophilus immobilization in a concentration- and time-dependent manner in vitro.
Intervention effect 0.5 mg/L His-AuNCs caused about 70% nematode immobility after 48 hours.
Intervention effect 0.5 mg/L PEI-AuNPs caused over 75% nematode immobility after 48 hours.
Intervention effect In feeding-based assays both gold nanomaterials suppressed nematode population expansion.
Observation Both nanoparticles were internalized by B. xylophilus and accumulated in internal tissues, particularly the anterior and intestinal regions.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L delayed symptom onset in pine seedlings.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L reduced disease severity in pine seedlings.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L preserved vascular integrity in pine seedlings.
Intervention effect PEI-AuNPs induced a focused stress response in the nematode, primarily upregulating heat shock proteins.
Intervention effect Both gold nanomaterials showed minimal acute toxicity in zebrafish assays.
Method / resource Green synthesis of His-AuNCs yielded monodisperse particles of 1.36 ± 0.05 nm with a zeta potential of -19.2 ± 0.3 mV.
Method / resource PEI-AuNPs were uniform spherical particles with a hydrodynamic diameter of 11.18 ± 0.9 nm.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

PEI-AuNPs induced a focused stress response in the nematode, primarily upregulating heat shock proteins.

Taxon: Bursaphelenchus xylophilusBursaphelenchus xylophilust0
Treatment: PEI-AuNPse7
Outcome: heat shock proteinse7
Direction: upregulatinge7

Not reportedComparator

Verbatim

e7
“PEI-AuNPs induced a focused stress response, primarily upregulating heat shock proteins”
✓ located verbatim in the source · abstract, characters 1657–1744

t0
“Bursaphelenchus xylophilus”
✓ located verbatim in the source · title, characters 122–148

Title

Physicochemically distinct gold nanomaterials suppress pine wilt disease through divergent nematicidal mechanisms against Bursaphelenchus xylophilus

Nabi Noor Ul Ghani; Qiannan Liu; Jie Qi; et al. Plant Nano Biology 2026. doi:10.1016/j.plana.2026.100286

Other claims from this paper (12)

Intervention effect Both gold nanomaterials induced B. xylophilus immobilization in a concentration- and time-dependent manner in vitro.
Intervention effect 0.5 mg/L His-AuNCs caused about 70% nematode immobility after 48 hours.
Intervention effect 0.5 mg/L PEI-AuNPs caused over 75% nematode immobility after 48 hours.
Intervention effect In feeding-based assays both gold nanomaterials suppressed nematode population expansion.
Observation Both nanoparticles were internalized by B. xylophilus and accumulated in internal tissues, particularly the anterior and intestinal regions.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L delayed symptom onset in pine seedlings.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L reduced disease severity in pine seedlings.
Intervention effect Stem injection of either nanomaterial at 0.05 mg/L preserved vascular integrity in pine seedlings.
Intervention effect His-AuNCs downregulated genes related to cuticle formation and metabolism in the nematode.
Intervention effect Both gold nanomaterials showed minimal acute toxicity in zebrafish assays.
Method / resource Green synthesis of His-AuNCs yielded monodisperse particles of 1.36 ± 0.05 nm with a zeta potential of -19.2 ± 0.3 mV.
Method / resource PEI-AuNPs were uniform spherical particles with a hydrodynamic diameter of 11.18 ± 0.9 nm.

Observationobservedoriginal resultmeasured

Claim · model-written summary

Two foliar nematode populations collected in Taiwan were identified as Aphelenchoides pseudobesseyi and Aphelenchoides oryzae.

Taxon: Aphelenchoides pseudobesseyi and Aphelenchoides oryzaeAphelenchoides pseudobesseyiAphelenchoides oryzaee0
Outcome: identifiede0
Setting: Taiwane0

Not reportedDirection

Verbatim

e0
“we identified Aphelenchoides pseudobesseyi and Aphelenchoides oryzae, two foliar nematode populations collected in Taiwan”
✓ located verbatim in the source · abstract, characters 268–389

Title

The Host Range and Pathogenic Potential Differences Between Aphelenchoides oryzae and Aphelenchoides pseudobesseyi

Che-Chang Liang; Jo-Tzu Ho; Pei-Chen Chen Phytopathology 2026. doi:10.1094/phyto-02-26-0056-r

Other claims from this paper (10)

Observationobservedoriginal resultmeasured

Claim · model-written summary

The two species differed consistently in post-vulval uterine sac length and male spicule structure.

Taxon: Aphelenchoides oryzae and Aphelenchoides pseudobesseyiAphelenchoides pseudobesseyiAphelenchoides oryzaet0
Outcome: differences in post-vulval uterine sac length and male spicule structuree0

Not reportedDirection

Verbatim

e0
“Morphological characterization revealed consistent differences in post-vulval uterine sac length and male spicule structure between the two species”
✓ located verbatim in the source · abstract, characters 473–620

t0
“Aphelenchoides oryzae and Aphelenchoides pseudobesseyi”
✓ located verbatim in the source · title, characters 60–114

Title

The Host Range and Pathogenic Potential Differences Between Aphelenchoides oryzae and Aphelenchoides pseudobesseyi

Che-Chang Liang; Jo-Tzu Ho; Pei-Chen Chen Phytopathology 2026. doi:10.1094/phyto-02-26-0056-r

Other claims from this paper (10)