Viruses 1,916 claims

Viruses and viroids. 49 families, 292 taxa.

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1,916 claims

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Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Compound 5z triggered the plant defense enzyme system.

Taxon: Tobacco mosaic virusTobacco mosaic viruse0
Treatment: 5ze3
Outcome: defense enzyme systeme7
Direction: triggeringe7

Not reportedComparator

Verbatim

e0
“Tobacco mosaic virus (TMV) is one of the most destructive plant pathogens”
✓ located verbatim in the source · abstract, characters 20–93

e3
“5z exhibited excellent protective and curative effects”
✓ located verbatim in the source · abstract, characters 360–414

e7
“simultaneously triggering the plant's defense enzyme system and boosting photosynthetic efficiency”
✓ located verbatim in the source · abstract, characters 973–1071

Title

Synthesis, antiviral activity and mechanistic insights into cytidine derivatives

Rui Wang; Yueling Qin; Ming Chen; et al. Pest Management Science 2026. doi:10.1002/ps.70728

Other claims from this paper (8)

Intervention effect Compound 5z exhibited excellent protective and curative effects against TMV.
Method / resource Compound 5z had an EC50 of 191.84 μg mL −1 against TMV.
Intervention effect Compound 5z outperformed the commercial agent ningnanmycin in EC50.
Intervention effect Compound 5z outperformed the commercial agent ribavirin in EC50.
Mechanism Compound 5z exerts antiviral effects by specifically binding the TMV coat protein.
Intervention effect Compound 5z boosted photosynthetic efficiency.
Recommendation The authors conclude that compound 5z shows strong promise as a novel antiviral agent.
Observation Structure-activity relationships were established for the cytidine derivatives.

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Compound 5z boosted photosynthetic efficiency.

Taxon: Tobacco mosaic virusTobacco mosaic viruse0
Treatment: 5ze3
Outcome: photosynthetic efficiencye7
Direction: boostinge7

Not reportedComparator

Verbatim

e0
“Tobacco mosaic virus (TMV) is one of the most destructive plant pathogens”
✓ located verbatim in the source · abstract, characters 20–93

e3
“5z exhibited excellent protective and curative effects”
✓ located verbatim in the source · abstract, characters 360–414

e7
“simultaneously triggering the plant's defense enzyme system and boosting photosynthetic efficiency”
✓ located verbatim in the source · abstract, characters 973–1071

Title

Synthesis, antiviral activity and mechanistic insights into cytidine derivatives

Rui Wang; Yueling Qin; Ming Chen; et al. Pest Management Science 2026. doi:10.1002/ps.70728

Other claims from this paper (8)

Intervention effect Compound 5z exhibited excellent protective and curative effects against TMV.
Method / resource Compound 5z had an EC50 of 191.84 μg mL −1 against TMV.
Intervention effect Compound 5z outperformed the commercial agent ningnanmycin in EC50.
Intervention effect Compound 5z outperformed the commercial agent ribavirin in EC50.
Mechanism Compound 5z exerts antiviral effects by specifically binding the TMV coat protein.
Intervention effect Compound 5z triggered the plant defense enzyme system.
Recommendation The authors conclude that compound 5z shows strong promise as a novel antiviral agent.
Observation Structure-activity relationships were established for the cytidine derivatives.

Recommendationauthor interpretationoriginal resultpositivebasis n/a

Claim · model-written summary

The authors conclude that compound 5z shows strong promise as a novel antiviral agent.

Taxon: Tobacco mosaic virusTobacco mosaic viruse0
Outcome: novel antiviral agente1

Verbatim

e0
“Tobacco mosaic virus (TMV) is one of the most destructive plant pathogens”
✓ located verbatim in the source · abstract, characters 20–93

e1
“5z shows strong promise as a novel antiviral agent”
✓ located verbatim in the source · abstract, characters 1309–1359

Title

Synthesis, antiviral activity and mechanistic insights into cytidine derivatives

Rui Wang; Yueling Qin; Ming Chen; et al. Pest Management Science 2026. doi:10.1002/ps.70728

Other claims from this paper (8)

Intervention effect Compound 5z exhibited excellent protective and curative effects against TMV.
Method / resource Compound 5z had an EC50 of 191.84 μg mL −1 against TMV.
Intervention effect Compound 5z outperformed the commercial agent ningnanmycin in EC50.
Intervention effect Compound 5z outperformed the commercial agent ribavirin in EC50.
Mechanism Compound 5z exerts antiviral effects by specifically binding the TMV coat protein.
Intervention effect Compound 5z triggered the plant defense enzyme system.
Intervention effect Compound 5z boosted photosynthetic efficiency.
Observation Structure-activity relationships were established for the cytidine derivatives.

Observationobservedoriginal resultmeasured

Claim · model-written summary

Structure-activity relationships were established for the cytidine derivatives.

Taxon: Tobacco mosaic virusTobacco mosaic viruse0
Outcome: relationships (SARs)e1

Verbatim

e0
“Tobacco mosaic virus (TMV) is one of the most destructive plant pathogens”
✓ located verbatim in the source · abstract, characters 20–93

e1
“relationships (SARs) were established for the cytidine derivatives”
✓ located verbatim in the source · abstract, characters 1103–1169

Title

Synthesis, antiviral activity and mechanistic insights into cytidine derivatives

Rui Wang; Yueling Qin; Ming Chen; et al. Pest Management Science 2026. doi:10.1002/ps.70728

Other claims from this paper (8)

Intervention effect Compound 5z exhibited excellent protective and curative effects against TMV.
Method / resource Compound 5z had an EC50 of 191.84 μg mL −1 against TMV.
Intervention effect Compound 5z outperformed the commercial agent ningnanmycin in EC50.
Intervention effect Compound 5z outperformed the commercial agent ribavirin in EC50.
Mechanism Compound 5z exerts antiviral effects by specifically binding the TMV coat protein.
Intervention effect Compound 5z triggered the plant defense enzyme system.
Intervention effect Compound 5z boosted photosynthetic efficiency.
Recommendation The authors conclude that compound 5z shows strong promise as a novel antiviral agent.

Observationobservedoriginal resultmeasured

Claim · model-written summary

The viral genome was 2,644 nucleotides long.

Taxon: Colocasia esculenta associated mitovirus 2Colocasia esculenta associated mitovirus 2e1
Organ / stage: symptomatic leaf tissuese0
Outcome: viral genomee0
Value: 2,644 nucleotide-longe0

Not reportedDirection

Verbatim

e0
“Analysis of symptomatic leaf tissues revealed a 2,644 nucleotide-long viral genome encoding a single open reading frame (ORF) for an RNA-dependent RNA polymerase (RdRp) of 544 amino acids”
✓ located verbatim in the source · abstract, characters 315–502

e1
“The viral sequence, tentatively named Colocasia esculenta associated mitovirus 2 (CeaMV2)”
✓ located verbatim in the source · abstract, characters 504–593

Title

Identification of a novel mitovirus in Colocasia esculenta through high‑throughput sequencing and in-silico miRNA prediction for sequence-specific gene silencing

Pooja Bhardwaj; Malyaj R Prajapati; Nitika Gupta; et al. International Microbiology 2026. doi:10.1007/s10123-026-00787-3

Other claims from this paper (9)

Observationobservedoriginal resultmeasured

Claim · model-written summary

The genome encoded a single ORF for a 544-amino-acid RdRp.

Taxon: Colocasia esculenta associated mitovirus 2Colocasia esculenta associated mitovirus 2e1
Outcome: RNA-dependent RNA polymerase (RdRp)e0
Value: 544 amino acidse0
Qualifier: single open reading frame (ORF)e0

Verbatim

e0
“viral genome encoding a single open reading frame (ORF) for an RNA-dependent RNA polymerase (RdRp) of 544 amino acids”
✓ located verbatim in the source · abstract, characters 385–502

e1
“The viral sequence, tentatively named Colocasia esculenta associated mitovirus 2 (CeaMV2)”
✓ located verbatim in the source · abstract, characters 504–593

Title

Identification of a novel mitovirus in Colocasia esculenta through high‑throughput sequencing and in-silico miRNA prediction for sequence-specific gene silencing

Pooja Bhardwaj; Malyaj R Prajapati; Nitika Gupta; et al. International Microbiology 2026. doi:10.1007/s10123-026-00787-3

Other claims from this paper (9)

Observationobservedoriginal resultmeasured

Claim · model-written summary

CeaMV2 had 60.76% amino acid identity with known mitoviruses, supporting novel species status.

Taxon: Colocasia esculenta associated mitovirus 2Colocasia esculenta associated mitovirus 2e0
Outcome: amino acid identitye0
Value: 60.76%e0
Qualifier: supporting its classification as a novel species within the family Mitoviridaee0
Comparator: known mitovirusese0

Verbatim

e0
“The viral sequence, tentatively named Colocasia esculenta associated mitovirus 2 (CeaMV2), showed 60.76% amino acid identity with known mitoviruses, supporting its classification as a novel species within the family Mitoviridae”
✓ located verbatim in the source · abstract, characters 504–731

Title

Identification of a novel mitovirus in Colocasia esculenta through high‑throughput sequencing and in-silico miRNA prediction for sequence-specific gene silencing

Pooja Bhardwaj; Malyaj R Prajapati; Nitika Gupta; et al. International Microbiology 2026. doi:10.1007/s10123-026-00787-3

Other claims from this paper (9)

Observationobservedoriginal resultmeasured

Claim · model-written summary

The mitovirus-specific RdRp domain was confirmed.

Taxon: Colocasia esculenta associated mitovirus 2Colocasia esculenta associated mitovirus 2e1
Outcome: presence of the mitovirus-specific RdRp domain (Pfam: PF05919)e0

Verbatim

e0
“The conserved domain searches confirmed the presence of the mitovirus-specific RdRp domain (Pfam: PF05919)”
✓ located verbatim in the source · abstract, characters 920–1026

e1
“The viral sequence, tentatively named Colocasia esculenta associated mitovirus 2 (CeaMV2)”
✓ located verbatim in the source · abstract, characters 504–593

Title

Identification of a novel mitovirus in Colocasia esculenta through high‑throughput sequencing and in-silico miRNA prediction for sequence-specific gene silencing

Pooja Bhardwaj; Malyaj R Prajapati; Nitika Gupta; et al. International Microbiology 2026. doi:10.1007/s10123-026-00787-3

Other claims from this paper (9)

Mechanismhypothesisoriginal resultmeasured

Claim · model-written summary

RdRp length and transcriptome expression suggest possible association with plant mitochondria.

Taxon: Colocasia esculenta associated mitovirus 2Colocasia esculenta associated mitovirus 2e1
Gene: RdRpe0
Outcome: possible association with plant mitochondriae0
Qualifier: relatively short RdRp and its expression in plant transcriptomee0

Verbatim

e0
“The relatively short RdRp and its expression in plant transcriptome suggest possible association with plant mitochondria”
✓ located verbatim in the source · abstract, characters 1128–1248

e1
“The viral sequence, tentatively named Colocasia esculenta associated mitovirus 2 (CeaMV2)”
✓ located verbatim in the source · abstract, characters 504–593

Title

Identification of a novel mitovirus in Colocasia esculenta through high‑throughput sequencing and in-silico miRNA prediction for sequence-specific gene silencing

Pooja Bhardwaj; Malyaj R Prajapati; Nitika Gupta; et al. International Microbiology 2026. doi:10.1007/s10123-026-00787-3

Other claims from this paper (9)

Observation A novel mitovirus was identified in Colocasia esculenta.
Observation The viral genome was 2,644 nucleotides long.
Observation The genome encoded a single ORF for a 544-amino-acid RdRp.
Observation CeaMV2 had 60.76% amino acid identity with known mitoviruses, supporting novel species status.
Observation CeaMV2 clustered with plant-associated mitoviruses within Mitoviridae.
Observation The mitovirus-specific RdRp domain was confirmed.
Observation RT-PCR and Sanger sequencing validated CeaMV2 in Colocasia leaves.
Observation In-silico analysis identified plant miRNAs including sbi-miR6231-3p with high affinity for CeaMV2 RdRp.
Mechanism The predicted miRNA binding suggests a potential RNA interference role in host-virus interactions.

Observationobservedreview summarybasis n/a

Claim · model-written summary

Geminiviridae comprises over 500 species, with diversity greater than previously recognized.

Taxon: GeminiviridaeGeminiviridaee0
Outcome: speciese0
Direction: greatere0
Value: over 500e0
Qualifier: than recognized previouslye0

Verbatim

e0
“The family Geminiviridae comprises over 500 species, and its diversity is now known to be much greater than recognized previously.”
✓ located verbatim in the source · abstract, characters 0–130

Title

Diversity of geminiviruses and impacts on global agriculture

K. KUBOTA Japanese Journal of Phytopathology 2026. doi:10.3186/jjphytopath.92.75

Other claims from this paper (3)