Intervention effectmodel-written summary

Transient silencing of NbSnRK1α increased accumulation of the NSs protein in Nicotiana benthamiana.

A claim from SnRK1α Restricts Tomato Spotted Wilt Virus Infection by Targeting the Viral Silencing Suppressor NSs for 26S Proteasome-Mediated Degradation · 2026

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Transient silencing of NbSnRK1α increased accumulation of the NSs protein in Nicotiana benthamiana.

Taxon
Nicotiana benthamianaNicotiana benthamianae5
Treatment
Transient silencing of NbSnRK1αe3
Gene
NbSnRK1αe3
Outcome
accumulation of the NSs proteine3
Direction
increasede3

Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Nicotiana benthamiana
Nicotiana benthamiana · TaxonCharles Andres · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e3

“Transient silencing of NbSnRK1α led to increased accumulation of the NSs protein”

✓ located verbatim in the source · abstract, characters 813–893
e5

“silencing NbSnRK1α enhances the susceptibility of Nicotiana benthamiana to TSWV infection and facilitates systemic viral spread and disease symptom development”

✓ located verbatim in the source · abstract, characters 1162–1321

Title

SnRK1α Restricts Tomato Spotted Wilt Virus Infection by Targeting the Viral Silencing Suppressor NSs for 26S Proteasome-Mediated Degradation

Xingwang Zhang; Yulong Yuan; Qinhai Liu; et al. Agronomy 2026. doi:10.3390/agronomy16030284

Other claims from this paper (7)

Record rev-737dcbbf95c27e325cc98d0d54075b81d94413362d20e44cedc7a458d3f988fc · schema claims-v0.9 · position 3 in the model’s answer

loss of function · quality: protein · Nicotiana benthamianaPositive and negative results

14 papers: 4 positive, 10 negative or no effect

9 papers in the same direction as this claim · 4 in the opposite direction

  1. positive
    Gene silencing of NbGAPDH-A inhibited localization of the movement protein to the cortical VRC.

    GAPDH-A Recruits a Plant Virus Movement Protein to Cortical Virus Replication Complexes to Facilitate Viral Cell-to-Cell Movement · 2014

    Opposite direction

  2. positive
    WRKY40 silencing abolished XopS prevention of stomatal closure in N. benthamiana.

    The Xanthomonas type-III effector XopS stabilizes Ca WRKY40a to regulate defense responses and stomatal immunity in pepper ( Capsicum annuum ) · 2022

    Opposite direction

  3. positive
    Deleting any of seven other residues reduced CP RNA-binding activity.

    Residues R192 and K225 in RNA-Binding Pocket of Tobacco Vein Banding Mosaic Virus CP Control Virus Cell-to-Cell Movement and Replication · 2021

    Opposite direction

  4. positive
    Silencing of formate dehydrogenase (FDH) or calreticulin-3 (CRT3) resulted in weak GFP signals of CMV-P1 in inoculated or upper leaves.

    Isolation and Characterization of Pepper Genes Involved in CMV-P1 Infection · 2016

    Opposite direction

  5. negative
    Silencing bZIP60 suppressed BiP and SKP1 transcripts.

    The Unfolded Protein Response Is Triggered by a Plant Viral Movement Protein     · 2011

    Same direction

  6. negative
    Deleting the TCV movement proteins abolished the movement complementation ability of TCV coat protein.

    A Versatile Assay for the Identification of RNA Silencing Suppressors Based on Complementation of Viral Movement · 2008

    Same direction

  7. negative
    Silencing PNbMTS1 by virus-induced gene silencing increased accumulation of BaMV coat protein and genomic RNA in N. benthamiana.

    Suppression of Bamboo Mosaic Virus Accumulation by a Putative Methyltransferase in Nicotiana benthamiana · 2009

    Same direction

  8. negative
    NbPLDα1 loss of function inhibited virus-induced MAPK activation.

    Activation of MAPK-mediated immunity by phosphatidic acid in response to positive-strand RNA viruses · 2023

    Same direction

5 papers more in this group

See all 14 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.