Claim · model-written summary
Disrupting NIP1;2 reduced plant arsenic content.
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianat0 - Treatment
- disruption of these genese0
- Gene
- NIP1;2e0
- Outcome
- As content in plantse0
- Direction
- reducede0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“NIP1;2 and NIP5;1, closely related homologs of NIP1;1, were also permeable to As(III). Although the disruption of these genes reduced the As content in plants”
t0“Arabidopsis thaliana”
Title
NIP1;1, an Aquaporin Homolog, Determines the Arsenite Sensitivity of Arabidopsis thaliana
Takehiro Kamiya; Mayuki Tanaka; Namiki Mitani; et al. Journal of Biological Chemistry 2008. doi:10.1074/jbc.m806881200
Other claims from this paper (12)
- Observation Three independent arsenite tolerant Arabidopsis mutants carried independent NIP1;1 mutations.
- Intervention effect Two NIP1;1 T-DNA lines were highly tolerant to arsenite.
- Observation NIP1;1 transported arsenite when expressed in Xenopus oocytes.
- Observation Arsenic content in NIP1;1 mutant plants was 30% below wild type.
- Observation NIP1;1 was highly expressed in roots.
- Observation GFP-NIP1;1 localized to the plasma membrane.
- Mechanism The authors infer that NIP1;1 mediates arsenite uptake into roots.
- Observation NIP1;2 was permeable to arsenite.
- Observation NIP5;1 was permeable to arsenite.
- Intervention effect Disrupting NIP5;1 reduced plant arsenic content.
- Observation Neither nip1;2 nor nip5;1 mutants showed arsenite tolerance.
- Mechanism The authors infer that lower plant arsenic content alone does not explain arsenite tolerance.