By organism › Green plants › Brassicaceae › Microthlaspi perfoliatum

Intervention effectobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

The methanol extract significantly reduced the viability of MCF-7 cells.

Taxon: Thlaspi perfoliatumMicrothlaspi perfoliatume1
Treatment: methanol extracte1
Outcome: viability of MCF-7 cellse0
Direction: reducede0

Not reportedComparator

Verbatim

e0
“MTT assay results revealed that the extract significantly reduced the viability of MCF-7 cells and inhibited cell proliferation, particularly at medium and high concentrations (400–1000 ppm)”
✓ located verbatim in the source · abstract, characters 269–459

e1
“Thlaspi perfoliatum methanol extract on human breast cancer cell line (MCF-7)”
✓ located verbatim in the source · abstract, characters 62–139

Title

ANTICLASTOGENIC POTENTIAL OF Thlaspi perfoliatum WITH MCF-7 CELLS AND Allium TEST

Nilsu Can; Yusuf Ceylan; Mehmet Cengiz Karaismailoglu Bartın University International Journal of Natural and Applied Sciences 2025. doi:10.55930/jonas.1738416

Other claims from this paper (4)

Intervention effectobservedoriginal resultpositivesignificant (as stated)measured

Claim · model-written summary

The methanol extract inhibited proliferation of MCF-7 cells, particularly at medium and high concentrations (400–1000 ppm).

Taxon: Thlaspi perfoliatumMicrothlaspi perfoliatume1
Treatment: methanol extracte1
Outcome: cell proliferatione0
Direction: inhibitede0
Qualifier: particularly at medium and high concentrations (400–1000 ppm)e0

Not reportedComparator

Verbatim

e0
“MTT assay results revealed that the extract significantly reduced the viability of MCF-7 cells and inhibited cell proliferation, particularly at medium and high concentrations (400–1000 ppm)”
✓ located verbatim in the source · abstract, characters 269–459

e1
“Thlaspi perfoliatum methanol extract on human breast cancer cell line (MCF-7)”
✓ located verbatim in the source · abstract, characters 62–139

Title

ANTICLASTOGENIC POTENTIAL OF Thlaspi perfoliatum WITH MCF-7 CELLS AND Allium TEST

Nilsu Can; Yusuf Ceylan; Mehmet Cengiz Karaismailoglu Bartın University International Journal of Natural and Applied Sciences 2025. doi:10.55930/jonas.1738416

Other claims from this paper (4)

Intervention effect The methanol extract significantly reduced the viability of MCF-7 cells.
Observation The LD50 value of the extract was 400–600 ppm, indicating a strong antiproliferative effect on cancer cells.
Intervention effect In Allium cepa root cells, the CuSO4-induced decrease in mitotic index recovered significantly at low and medium doses.
Intervention effect In the A. cepa model, chromosomal abnormalities decreased depending on the dose and application time.

Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

The LD50 value of the extract was 400–600 ppm, indicating a strong antiproliferative effect on cancer cells.

Taxon: Thlaspi perfoliatumMicrothlaspi perfoliatume1
Outcome: LD₅₀ valuee2
Value: 400–600 ppme2

Verbatim

e1
“Thlaspi perfoliatum methanol extract on human breast cancer cell line (MCF-7)”
✓ located verbatim in the source · abstract, characters 62–139

e2
“The LD₅₀ value ranging between 400–600 ppm indicates that the extract has a strong antiproliferative effect on cancer cells”
✓ located verbatim in the source · abstract, characters 461–584

Title

ANTICLASTOGENIC POTENTIAL OF Thlaspi perfoliatum WITH MCF-7 CELLS AND Allium TEST

Nilsu Can; Yusuf Ceylan; Mehmet Cengiz Karaismailoglu Bartın University International Journal of Natural and Applied Sciences 2025. doi:10.55930/jonas.1738416

Other claims from this paper (4)

Intervention effect The methanol extract significantly reduced the viability of MCF-7 cells.
Intervention effect The methanol extract inhibited proliferation of MCF-7 cells, particularly at medium and high concentrations (400–1000 ppm).
Intervention effect In Allium cepa root cells, the CuSO4-induced decrease in mitotic index recovered significantly at low and medium doses.
Intervention effect In the A. cepa model, chromosomal abnormalities decreased depending on the dose and application time.

Observationobservedoriginal resultmeasured

Claim · model-written summary

The strains represent a distinct phylogenetic lineage most closely related to Equiseticola and Ophiosphaerella.

Taxon: Microthlaspi perfoliatumMicrothlaspi perfoliatume1
Material: fungal strainse1
Outcome: distinct phylogenetic lineagee2

Verbatim

e1
“fungal strains were investigated, which had been isolated from eggs of the cereal cyst nematode Heterodera filipjevi, and roots of Microthlaspi perfoliatum (Brassicaceae)”
✓ located verbatim in the source · abstract, characters 14–184

e2
“The strains were found to represent a distinct phylogenetic lineage most closely related to Equiseticola and Ophiosphaerella, and Polydomus karssenii (Phaeosphaeriaceae, Pleosporales) is introduced here as a new species representing a monotypic genus”
✓ located verbatim in the source · abstract, characters 507–757

Title

Polydomus karssenii gen. nov. sp. nov. is a dark septate endophyte with a bifunctional lifestyle parasitising eggs of plant parasitic cyst nematodes (Heterodera spp.)

Samad Ashrafi; Jan-Peer Wennrich; Yvonne Becker; et al. IMA Fungus 2023. doi:10.1186/s43008-023-00113-w

Other claims from this paper (8)

Observationobservedoriginal resultbasis n/a

Claim · model-written summary

Polydomus karssenii is introduced as a new species representing a monotypic genus.

Taxon: Microthlaspi perfoliatumMicrothlaspi perfoliatume1
Outcome: new speciese2
Qualifier: representing a monotypic genuse2

Verbatim

e1
“fungal strains were investigated, which had been isolated from eggs of the cereal cyst nematode Heterodera filipjevi, and roots of Microthlaspi perfoliatum (Brassicaceae)”
✓ located verbatim in the source · abstract, characters 14–184

e2
“The strains were found to represent a distinct phylogenetic lineage most closely related to Equiseticola and Ophiosphaerella, and Polydomus karssenii (Phaeosphaeriaceae, Pleosporales) is introduced here as a new species representing a monotypic genus”
✓ located verbatim in the source · abstract, characters 507–757

Title

Polydomus karssenii gen. nov. sp. nov. is a dark septate endophyte with a bifunctional lifestyle parasitising eggs of plant parasitic cyst nematodes (Heterodera spp.)

Samad Ashrafi; Jan-Peer Wennrich; Yvonne Becker; et al. IMA Fungus 2023. doi:10.1186/s43008-023-00113-w

Other claims from this paper (8)

Observationobservedoriginal resultmeasured

Claim · model-written summary

The fungus parasitised eggs of its original host Heterodera filipjevi and of the sugar beet cyst nematode H. schachtii, fulfilling Koch's postulates in vitro.

Taxon: Microthlaspi perfoliatumMicrothlaspi perfoliatume1
Interactor: H. filipjeviHeterodera filipjevie3host
Second interactor: H. schachtiiHeterodera schachtiie3host
Outcome: parasitisee3
Qualifier: fulfilled Koch's postulates using in vitro nematode bioassayse3

Verbatim

e1
“fungal strains were investigated, which had been isolated from eggs of the cereal cyst nematode Heterodera filipjevi, and roots of Microthlaspi perfoliatum (Brassicaceae)”
✓ located verbatim in the source · abstract, characters 14–184

e3
“The pathogenicity tests against nematode eggs fulfilled Koch's postulates using in vitro nematode bioassays and showed that the fungus could parasitise its original nematode host H. filipjevi as well as the sugar beet cyst nematode H. schachtii”
✓ located verbatim in the source · abstract, characters 759–1003

Title

Polydomus karssenii gen. nov. sp. nov. is a dark septate endophyte with a bifunctional lifestyle parasitising eggs of plant parasitic cyst nematodes (Heterodera spp.)

Samad Ashrafi; Jan-Peer Wennrich; Yvonne Becker; et al. IMA Fungus 2023. doi:10.1186/s43008-023-00113-w

Other claims from this paper (8)

Observationobservedoriginal resultmeasured

Claim · model-written summary

The fungus colonised cysts and eggs of its hosts by forming highly melanised moniliform hyphae.

Taxon: Microthlaspi perfoliatumMicrothlaspi perfoliatume1
Outcome: colonise cysts and eggse4
Qualifier: by forming highly melanised moniliform hyphaee4

Verbatim

e1
“fungal strains were investigated, which had been isolated from eggs of the cereal cyst nematode Heterodera filipjevi, and roots of Microthlaspi perfoliatum (Brassicaceae)”
✓ located verbatim in the source · abstract, characters 14–184

e4
“colonise cysts and eggs of its hosts by forming highly melanised moniliform hyphae”
✓ located verbatim in the source · abstract, characters 1009–1091

Title

Polydomus karssenii gen. nov. sp. nov. is a dark septate endophyte with a bifunctional lifestyle parasitising eggs of plant parasitic cyst nematodes (Heterodera spp.)

Samad Ashrafi; Jan-Peer Wennrich; Yvonne Becker; et al. IMA Fungus 2023. doi:10.1186/s43008-023-00113-w

Other claims from this paper (8)

Observationobservedoriginal resultmeasured

Claim · model-written summary

Different strains of the new fungus produced a nearly identical set of secondary metabolites with various biological activities, including nematicidal effects, irrespective of their origin.

Taxon: Microthlaspi perfoliatumMicrothlaspi perfoliatume1
Material: strainse2
Outcome: a nearly identical set of secondary metabolitese2
Qualifier: various biological activities including nematicidal effects irrespective of their origin from plants or nematodese2

Verbatim

e1
“fungal strains were investigated, which had been isolated from eggs of the cereal cyst nematode Heterodera filipjevi, and roots of Microthlaspi perfoliatum (Brassicaceae)”
✓ located verbatim in the source · abstract, characters 14–184

e2
“Different strains of the new fungus produced a nearly identical set of secondary metabolites with various biological activities including nematicidal effects irrespective of their origin from plants or nematodes”
✓ located verbatim in the source · abstract, characters 1658–1869

Title

Polydomus karssenii gen. nov. sp. nov. is a dark septate endophyte with a bifunctional lifestyle parasitising eggs of plant parasitic cyst nematodes (Heterodera spp.)

Samad Ashrafi; Jan-Peer Wennrich; Yvonne Becker; et al. IMA Fungus 2023. doi:10.1186/s43008-023-00113-w

Other claims from this paper (8)

Observationobservedoriginal resultsignificant (as stated)measured

Claim · model-written summary

In M. perfoliatum the root Zn concentration was significantly higher than the shoot concentration.

Taxon: M. perfoliatumMicrothlaspi perfoliatume1
Organ / stage: rootse1
Outcome: Zn concentration in the rootse1
Direction: highere1
Comparator: the shootse1

Verbatim

e1
“In M. perfoliatum, the Zn concentration in the roots was significantly higher than in the shoots”
✓ located verbatim in the source · abstract, characters 702–798

Title

I. V. Seregin; A. D. Kozhevnikova; H. Schat Russian Journal of Plant Physiology 2021. doi:10.1134/s1021443721070128

Other claims from this paper (14)

Observationobservedoriginal resultmeasured

Claim · model-written summary

In M. perfoliatum the translocation factor was the lowest of the species compared.

Taxon: M. perfoliatumMicrothlaspi perfoliatume6
Outcome: translocation factor (TF)e6
Direction: loweste6

Verbatim

e6
“The value of the translocation factor (TF) was the lowest in the excluder M. perfoliatum”
✓ located verbatim in the source · abstract, characters 1505–1593

Title

I. V. Seregin; A. D. Kozhevnikova; H. Schat Russian Journal of Plant Physiology 2021. doi:10.1134/s1021443721070128

Other claims from this paper (14)

Microthlaspi perfoliatum 36 claims

36 claims